Open access peer-reviewed Edited Volume

The Erythrocyte - A Unique Cell

Vani Rajashekaraiah

Jain University

Dr. Vani Rajashekaraiah, Associate Professor, JAIN (Deemed-to-be University), Bangalore has 20 years of research experience in Oxidative Stress Physiology and Hematology and 16 years of teaching experience. She has authored numerous journal papers and book chapters and has one published patent. She has received CSIR research fellowship and is a Member of the Society for Free Radical Research, India.


Erythrocyte Hemoglobin Erythrocyte Aging Pathways Metabolites Deficiencies Membrane Changes Band 3 Deformability Hemolysis Disease Conditions Free Radical Initiators

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About the book

The Erythrocyte is unique and forms a model for studying various situations/ physiological conditions.
This cell has evolved an effective defense system to counteract the challenges as it is always in an oxygen-rich environment. The evolution of hemoglobin and deformability of erythrocyte membrane adapting to its function in circulation is especially striking. Erythrocyte aging and eryptosis strike a balance - the mixed population of cells and constant recycling every 120 days is a very distinct feature. Its metabolic shunt pathways and metabolites/enzymes alter and adapt with age and changes in the microenvironment.

Erythrocyte and its cytoskeleton responses to various situations such as infections, hypoxia, hypothermia, intrigues researchers and biologists alike. This book aims to throw light on the significance of erythrocyte and its characteristic nature and survival in different physiological situations as it plays a very crucial role.

This book hopes to bring different perspectives from various aspects and provide insights into the effective mechanisms evolved by erythrocytes, to counteract the challenges faced in its oxidation environment and the further research approaches.

Publishing process

Book initiated and editor appointed

Date completed: March 24th 2022

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline for chapter proposals: May 26th 2022

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Approved chapters written in full and submitted

Deadline for full chapters: July 25th 2022

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: October 13th 2022

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: December 12th 2022

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About the editor

Vani Rajashekaraiah

Jain University

Teaching Experience: 16 years • Associate Professor in Biotechnology, School of Sciences, Block I, JAIN (Deemed-to-be University), Bengaluru from May 2018 till date. (Courses: Molecular Genetics, Molecular Biology and Genetic Engineering). Research Experience: 20 years in the field of Oxidative Stress Physiology and hematology. Current Research focus: Blood Storage (erythrocytes, platelets) and Drug-induced Thrombocytopenia Total publications in SCOPUS / Web of Science: 27 and International book chapters: 04. Research guidance: 3 PhD students (completed); 3 PhD students guiding currently. Six years of research experience as JRF (CSIR) and SRF (CSIR) in the field of High Altitude Physiology and Biochemistry, specialization in Oxidative Stress Physiology, from August 2002 to 2008. o Pursued research under the guidance of Dr. S. Asha Devi, Professor, Dept. of Zoology, Bangalore University, Bangalore-560056, towards Ph.D in Zoology. Title of the thesis- “Studies on Oxidative Stress in Erythrocytes of Rats Exposed to Intermittent Hypobaric Hypoxia”.

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