About the book
Doxorubicin chemotherapy it has been obtained from Streptomyces peucetius which is a bacterium species, considered as one of the dominant anti-cancer treatments which approved by the U.S. Food and Drug Administration (FDA) in 1995, and it widely used for treating several types of cancers like: ovarian, breast, lung, uterine and cervical cancers, Hodgkin’s disease, soft tissue and primary bone sarcomas, and others.
But both of its usage and effectiveness are limited because of the critical side effects happened while using it and drug-resistance. Regarding side effects they mainly happened as a result of the free radicals produced by doxorubicin. While, drug-resistance is mainly happened because of gene mutation. Even many books published about doxorubicin but few if any focused on the molecular mechanism of doxorubicin’s critical side effects, on medicinal herbs that can be used to palliate and/or treat these side effects, and on gene mutation and drug-resistance.
Many researchers highly recommended future books, studies, and review studies to focus on these two points. Therefore, proposed book is trying to focus on these two points to elucidate all of them.