Open access peer-reviewed Edited Volume

Chronic Kidney Disease - Beyond the Basics

Ane Claudia Fernandes Nunes

University of California, Irvine

Dr. Ane C.F. Nunes received her Ph.D. degree in Medical Sciences and Nephrology from the Federal University of Rio Grande do Sul (Brazil) and has obtained postdoctoral experience in Renal Physiology at the Federal University of Rio de Janeiro (Brazil), Clinical Medicine and Nephrology at the University of São Paulo (Brazil), and Nephrology and Hypertension at the University of California, Irvine (USA).


Chronic Kidney Disease Kidney Acute Renal Injury Renal Disease Filtration Management Renal Function Nephrology Kidney Function Renal Physiology Hemodialysis Peritoneal Dialysis Transplantation

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About the book

Chronic kidney disease (CKD) is the sixteenth biggest cause of reduction of life expectancy worldwide. Appropriate screening, diagnosis, and management by primary care clinicians are necessary to prevent adverse CKD-associated outcomes, including cardiovascular disease, end-stage kidney disease, and death. From the clinical point of view, it is a longstanding disease of the kidneys leading to renal failure. The kidney’s main function, beyond its hormonal and enzymatic production, is to filter the metabolites and surplus fluids from the blood. When the kidney reduces its filtration capacity, these vestigial products build-up, and CKD is established. Renal failure is a progressive condition with symptoms that develop slowly and are not specific to the disease itself. In some cases, the diagnosis is based on laboratory tests only, without major clinical manifestations. In terms of conservative treatment, some medication helps manage the symptoms, possibly increasing the life expectancy. In later phases, artificial filtration methods may be required, such as ambulatorial dialysis and peritoneal dialysis. The gold standard solution is renal transplantation. However, this is not an easily done procedure in some situations, whether due to immunological incompatibilities or strategic public health plans incapable of meeting the demands. Classically, CKD was associated with aging or inherited disorders. However, it is currently observed in different age ranges and linked to modern lifestyles issues (dietary preferences, sedentarism, obesity, diabetes, hypertension, and other potentially unbalanced conditions of human health), even in patients with no other risk factors.

Publishing process

Book initiated and editor appointed

Date completed: November 30th 2021

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline for chapter proposals: January 2nd 2022

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Approved chapters written in full and submitted

Deadline for full chapters: March 1st 2022

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: May 20th 2022

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: July 19th 2022

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About the editor

Ane Claudia Fernandes Nunes

University of California, Irvine

Dr. Ane C.F. Nunes is a geneticist with a master’s degree and Ph.D. in Medical Sciences and Nephrology from UFRGS/Brazil. She has postdoctoral experience in renal physiology (UFRJ/Brazil), clinical medicine and nephrology (USP/Brazil), and nephrology and hypertension (UCI/USA). She is a Professor of Medical Genetics, Human Genetics, and Molecular Biology. Her research fields are human genetics diseases, cellular and molecular biology applied to nephrology, biochemistry, and microbiology with projects in the following subjects: inflammatory markers, molecular diagnosis, DNA polymorphisms, chronic kidney disease (CKD), polycystic kidney disease (PKD), Fabry disease, rare diseases, cellular and murine models for CKD, RNA processing, fluorescent image analysis, nanoparticles development, and nanomedicine.

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Book chapters authored 5

Books edited 3

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