About the book
Mechanobiology represents a special coupling between biology and mechanical engineering. It describes the way in which biological cells detect, respond, and react to the actions of their mechanical operating environment. Biological cells are not only able to detect biochemical signals but also mechanical factors such as stress, geometry, and matrix elasticity. Recent advances in this field have improved our understanding of how mechanical inputs orchestrate the cellular dynamic behavior and tissue regeneration of living systems. Research in mechanobiology also explains how deregulation of mechanical parameters can cause or induce disease. It is a very complex multidisciplinary research discipline that requires many skills and tools, both numerical and experimental.
This book will mainly cover work related to: (i) cells mechanosensing and mechanotransduction mechanisms (ii) computational and experimental techniques in mechanobiology, (iii) mathematical mechanobiological models of bone remodeling, (iv) bone mechano-transduction, (v) innovative tools for mechanobiology and the role of medical imaging in this field and (vi) any other proposals related to innovations, clinical application and perspectives of mechanobiology.