Open access peer-reviewed Edited Volume

Takotsubo Sydrome

Neelima Katukuri

University of Central Florida


Skeletal Muscle Development Skeletal Muscle Regeneration Molecular Pathways Nitric Oxide Signaling Pluripotent Stem Cells iPS Cells miRNA Profiling Serum Biomarkers Muscle Biopsy Next Generation Sequencing Utrophin Upregulation Antisense Oligonucleotides

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About the book

Stress cardiomyopathy (Takotsubo cardiomyopathy) is a syndrome characterized by left ventricular dysfunction in the absence of coronary artery disease. Underlying pathogenesis includes catecholamine excess, microvascular dysfunction, and multi vessel coronary artery spasm. The diagnosis of stress cardiomyopathy should be suspected in adults who present with a suspected acute coronary syndrome, with symptoms such as chest pain or dyspnea in combination with electrocardiographic changes and/or cardiac troponin elevation, particularly when the clinical manifestations and electrocardiographic abnormalities are out of proportion to the degree of elevation in cardiac biomarkers. Diagnostic criteria include presence of transient regional wall motion abnormalities typically not in a single coronary distribution, absence of angiographic evidence of obstructive coronary disease or acute plaque rupture, presence of new electrocardiographic abnormalities or modest troponin elevation, and absence of pheochromocytoma or myocarditis. Wall motion abnormalities in patients with stress cardiomyopathy are typically detected by echocardiography or left ventriculography. Patterns of left ventricular wall motion abnormality in patients with stress cardiomyopathy include the apical type which occurs in the most cases, and atypical variants including mid-ventricular, basal, focal -limited to an isolated segment, and global types.

Publishing process

Book initiated and editor appointed

Date completed: November 27th 2019

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Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

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Approved chapters written in full and submitted

Deadline for full chapters: May 26th 2020

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Review results due: August 14th 2020

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Expected publication date: October 13th 2020

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About the editor

Neelima Katukuri

University of Central Florida

Dr. Neelima Katukuri is a board-certified Cardiologist practicing as Interventional Cardiologist at Orlando VA Medical Center (Florida, USA) where she serves as Staff Interventional Cardiologist. She currently holds appointments and serves on the teaching faculty at University of Central Florida College of Medicine. She received her Internal Medicine training at Wayne State University/ Detroit Medical Center and completed a Fellowship in Interventional Cardiology at The University of Tennessee. She is an active member of the American Society of Nuclear Cardiology, the American College of Cardiology (ACC), Women in Cardiology, Women in Innovations and the Society of Cardiovascular Angiography and Interventions. She is the author of well over 20 peer-reviewed manuscripts, abstracts, and book chapters. She has edited various topics ranging from cardiac imaging, aqueous oxygen in acute myocardial infarction and women’s heart disease.

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