Open access peer-reviewed Edited Volume

Gastroesophageal Reflux Disease - A Growing Concern

Jianyuan Chai

Baotou Medical College

Dr. Jianyuan Chai completed his postdoctoral training at Harvard University in 2001 and afterward served at the United States Department of Veterans Affairs as a Principal Investigator. He is a member of several professional organizations including the American Gastroenterological Association, Expertscape in Obesity, and the American Society for Biochemistry and Molecular Biology.


Gastroesophageal Reflux Disease GERD Heartburn Obesity Diet Esophagitis Barrett's Esophagus Esophageal Cancer Acid Reflux Bile Reflux Proton Pump Inhibitor Acid-Suppressive Drugs

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About the book

Gastroesophageal reflux disease (GERD) is the most common gastrointestinal diagnosis nowadays. GERD occurs when the lower esophageal sphincter fails to block the stomach content to go up into the esophagus. The refluxate not only contains strong acid but sometimes also bile from the duodenum. Chronic GERD can lead to esophageal cancer, which is one of the deadliest malignancies in the world. A recent study shows that GERD increases the risk of esophageal adenocarcinoma by 8.6 fold. GERD is usually treated with acid-suppressive drugs like PPI, or with surgical procedures, but multiple side effects are reported repeatedly. Moreover, these treatment strategies have not been found to lower the risk of esophageal cancer. This book aims to cover every aspect of GERD, particularly its epidemiology, pathophysiology, molecular biology, as well as treatment options. Through this book, we hope to raise more awareness of this common disease, leading to more effective treatment strategies.

Publishing process

Book initiated and editor appointed

Date completed: April 7th 2022

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline for chapter proposals: June 16th 2022

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Approved chapters written in full and submitted

Deadline for full chapters: August 15th 2022

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: November 3rd 2022

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: January 2nd 2023

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About the editor

Jianyuan Chai

Baotou Medical College

Dr. Chai received his Ph.D. in Biology from the City University of New York in 1998 and completed his postdoctoral training in molecular medicine at Harvard University in 2001. Then he served the Department of Veterans Affairs of the United States as a Principal Investigator (2002-2016) in affiliation with the School of Medicine, University of California in Irvine. Currently, he is a professor at Baotou Medical College in China. He has published dozens of research articles on various subjects including zoology, cardiovascular biology, gastroenterology, and cancer biology. He has been a member of AGA, AHA, ASBMB, and several other professional organizations, and has also served on the editorial board of multiple journals. His current research mainly focuses on the molecular dynamics of esophageal cancer.

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Book chapters authored 5

Books edited 6

Introducing your Author Service Manager

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