Open access peer-reviewed Edited Volume

Latest Breakthroughs in Understanding and Treating Angioedema and Urticaria

Charbel Skayem

Assistance Publique -Hopitaux De Paris

Dr. Charbel Skayem is a dermatologist and venereologist in Assistance Publique-Hôpitaux de Paris(AP-HP), the largest university hospital system in Europe, and Gustave Roussy, the first cancer research hospital in Europe and among the top 5 best-specialized hospitals in the world. Dr. Skayem graduated from the Sorbonne University, University of Paris, and Paris-Saclay University, and is a member of several dermatological societies and academies, and the author of numerous articles in top leading journals.


Tu Anh Duong

Assistance Publique -Hopitaux De Paris

Dermatologist in Assistance Publique des Hôpitaux de Paris (AP-HP), the largest university hospital system in Europe, Paris-Saclay University, and a numeric design engineer in medicine. President of teledermatology in the French Society of dermatology and coordinator of TELDERM AP-HP.


Hereditary C1 Inhibitor C1q IgE-Mediated Non-IgE-Mediated Histamine Degranulation Mast Cells Neuropeptide Hypersensitivity Auto-Immune Anti-histamine

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About the book

Despite being common dermatological disorders, angioedema and urticaria have been poorly understood throughout history. The real cause of developing their unpredictable debilitating symptoms has remained a mystery among doctors and scientists for years. However, the past decade was a turning point in uncovering the pathophysiology of these entities and discovering new treatments for cases that are resistant to conventional therapy. This book will discuss the most recent breakthroughs in the molecular mechanism of angioedema and urticaria, while providing updates on the newest possible etiologies and causes of these conditions, including hereditary angioedema with or without C1 inhibitor deficiency, FXII-related malfunctions, and chronic spontaneous urticaria (CSU). Moreover, the book intends to underline the latest treatments that have revolutionized the management of these diseases, with a focus on the different rising therapies in resistant cases, especially the newest monoclonal antibodies. This will update dermatologists and physicians on the myriad options we can use in cases that were once considered impossible to treat.

Publishing process

Book initiated and editor appointed

Date completed: April 20th 2022

Applications to edit the book are assessed and a suitable editor is selected, at which point the process begins.

Chapter proposals submitted and reviewed

Deadline Extended: Open for Submissions

Potential authors submit chapter proposals ready for review by the academic editor and our publishing review team.

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Approved chapters written in full and submitted

Deadline for full chapters: July 17th 2022

Once approved by the academic editor and publishing review team, chapters are written and submitted according to pre-agreed parameters

Full chapters peer reviewed

Review results due: October 5th 2022

Full chapter manuscripts are screened for plagiarism and undergo a Main Editor Peer Review. Results are sent to authors within 30 days of submission, with suggestions for rounds of revisions.

Book compiled, published and promoted

Expected publication date: December 4th 2022

All chapters are copy-checked and typesetted before being published. IntechOpen regularly submits its books to major databases for evaluation and coverage, including the Clarivate Analytics Book Citation Index in the Web of ScienceTM Core Collection. Other discipline-specific databases are also targeted, such as Web of Science's BIOSIS Previews.

About the editor

Charbel Skayem

Assistance Publique -Hopitaux De Paris

Dr Charbel Skayem is a dermatologist, venereologist, and dermatologic surgeon practicing in Assistance Publique des Hôpitaux de Paris (AP-HP), the largest university hospital system in Europe and one of the largest in the world, and in Gustave Roussy, the first cancer-research hospital in Europe and among the top 5 best specialized university hospitals in the world. Lebanese in origin, he moved to Paris to pursue his residency in dermatology and venereology, followed by several fellowships, graduating from the Sorbonne University, the University of Paris, and Paris-Saclay University. His initial experiences in different worldwide-renowned pioneer referral departments have given him a wide expertise in multiple branches of his specialty: oncodermatology, advanced dermatologic surgery, inflammatory and infectious dermatology, teledermatology, sexually transmitted diseases, and cosmetic and laser dermatology. Dr Skayem is a member of different dermatological societies and academies. He was a laureate of several scholarships and awards. He was a distinguished speaker in many global congresses. Despite his youth, he served as a reviewer and editor, has written several chapters in books, and numerous articles in leading peer-reviewed medical journals.

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