Norman Chiu

University of North Carolina at GreensboroUnited States of America

Dr. Norman H. L. Chiu is an Associate Professor of Chemistry at the University of North Carolina at Greensboro, USA. He is also an affiliated member of the Joint School of Nanoscience and Nanoengineering in Greensboro, and the Comprehensive Cancer Center at the Wake Forest University. He received his B.Sc. in Chemistry from the University of Liverpool, UK, M.Sc. in Analytical Chemistry from the University of Bristol, UK, and Ph.D. in Biochemistry from the University of Windsor, Canada. He and Dr. Theodore Christopoulos were the first to develop an expressible enzyme-coding DNA label for immunoassays. As a Postdoctoral Research Fellow, he extended his research experience on method development with Dr. Charles R. Cantor at Boston University and Sequenom Inc, USA.

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Latest work with IntechOpen by Norman Chiu

From the basic in vitro study of a specific biomolecule to the diagnosis or prognosis of a specific disease, one of the most widely used technology is immunoassays. By using a specific antibody to recognize the biomolecule of interest, relatively high specificity can be achieved by immunoassays, such that complex biofluids (e.g. serum, urine, etc.) can be analyzed directly. In addition to the binding specificity, the other key features of immunoassays include relatively high sensitivity for the detection of antibody-antigen complexes, and a wide dynamic range for quantitation. Over the past decade, the development and applications of immunoassays have continued to grow exponentially. This book focuses on some of the latest technologies for the development of new immunoassays.

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