Christopher J. Payne

Northwest UniversityUnited States of America

Dr. Christopher J. Payne is an Assistant Professor in the Departments of Pediatrics and Obstetrics & Gynecology at Northwestern University's Feinberg School of Medicine and the Human Molecular Genetics Program at the Ann & Robery H. Lurie Children's Hospital of Chicago Research Center in Chicago, Illinois. He received his Bachelor of Science degree from the University of Washington and his Ph.D. in Cell and Developmental Biology from the Oregon Health and Science University in 2003. Dr. Payne's current research focuses on the epigenetic regulation of tissue-specific stem cells and how this influences male fertility. His laboratory demonstrated that the histone deacetylase protein complex SIN3 is essential for the maintenance of spermatogonial stem cells in the testis.

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Latest work with IntechOpen by Christopher J. Payne

The book aims to provide an overview of current knowledge regarding epigenetics and epigenomics. Included are reviews on the role of epigenetics in the development and pathogenesis of the vascular endothelium and nervous system, as well as our current understanding of the potential etiologies of Autism Spectrum Disorders. Additional chapters are devoted to DNA methylation, genomic imprinting and human reproduction. A discussion of the role of the epigenome in cancer prevention and polyphenols is also included. Authors provide research findings from both human data and animal model studies. This book will be of interest to scientists, physicians and lay readers wishing to review recent developments in the field of epigenetics and epigenomics.

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