Willard James Costain

National Research Council CanadaCanada

Dr. Will Costain is a Research Officer and Team Leader In Vitro Pharmacology at National Research Council of Canada. He holds a B.Sc. in Physiology from University of Saskatchewan; a M.Sc. in Physiology from University of Saskatchewan and a Ph.D. in Physiology and Pharmacology from McMaster University. He also holds a Post-Doc in Pharmacology from Dalhousie University. He leads a team of researchers who focus on enabling the development of biologic therapeutics for CNS diseases. They focus on in vitro models of the blood brain barrier and cell-based assays for assessing drug pharmacology. Dr. Costain\'s primary interest is in characterizing the pharmacology and signaling mechanisms of small and large molecule therapeutics. Over the years, he has studied a variety of GPCR systems using classical pharmacological techniques. He has also used genomic methods to characterize genomic responses to brain injury and mutations.

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Latest work with IntechOpen by Willard James Costain

Scientific interest in cannabinoid research is currently experiencing a significant increase because of changing attitudes toward Cannabis and the evolving awareness of its pharmaceutical benefits. Coincidently, numerous jurisdictions are moving toward legalizing Cannabis and Cannabis-derived products, which reflects a larger global movement to understand Cannabis and its bioactive chemicals for their potential biomedical uses, harms, and economic value. Research activities are surging to fill important knowledge gaps in the field of cannabinoids as they continue to be identified. The purpose of this book is to summarize some leading areas of research in the cannabinoid field where knowledge gaps are actively being addressed. The research described herein spans basic biological and clinical research.

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