Mei Yang

CURRICULUM VITAE Mei Yang, MD, PhD, MS, CCRP E-mail: myang15@tulane.edu EDUCATION: 9/1999 - 7/2004 DALIAN MEDICAL UNIVERSITY, CHINA, MD • Clinical rotations in internal medicine, surgery, Obstetrics and Gynecology, Pediatrics, and Psychiatry • Learned to take patient history, complete physical exams, diagnose disease, surgery assistance, medical procedures and common medical conditions 9/2004 - 7/2007 HARBIN MEDICAL UNIVERSITY, CHINA, MASTER • Three years’ residency training including clinical rotations in trauma center, orthopedics, surgical oncology, craniomaxillofacial surgery and training in plastic surgery • Clinical training in both inpatient and outpatient settings 9/2007 – 5/2010 SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE, CHINA, PHD • Two years’ research training and one year clinical training • Became research team lead and published paper (PMID: 21508815) with highest impact factor at the institution • Designed clinical trial, and published results (PMID: 27876353) in EBioMedicine (The Lancet) • 5 first-author papers generated during the PhD program WORK EXPERIENCE 06/2021-NOW MD, DEPARTMENT OF NEUROLOGY, TULANE UNIVERSITY SCHOOL OF MEDICINE • Clinical training in both internal medicine and neurology • Involve in multiple research projects: migraine, telemedicine, COVID, et al 01/2017 – 05/2021 SENIOR CLINICAL RESEARCH COORDINATOR, UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER • Provide research guidance to treating providers for consideration during care planning. • Managed 7 Investigational New Drug (IND) clinical trials, 6 investigator-initiated trials, and 3 investigational device exemption (IDE) clinical trials • Experience with Phase I, II, III clinical trials 05/2011 – 01/2014 RESEARCH ASSOCIATE, SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE • Research areas included gene therapy for breast cancer (animal models) and treatment of Raynauld’s syndrome, and scleroderma (clinical studies). • Contributed to grant proposal writing, generating 8 successful applications with funded roles: Principal Investigator (Plastic Surgery Foundation), Co-Investigator (Plastic Surgery Foundation, Memorial Medical Center Foundation (x5), National Endowment for Plastic Surgery) • 8 manuscripts generated during position. 05/2010 – 04/2011 VISITING SCHOLAR, UNIVERSITY OF MISSISSIPPI MEDICAL CENTER • Research in ischemia • 6 manuscripts generated during position AWARDS/ACHIEVEMENTS 2008 Robert Zhong Award at 9th International Experimental Microsurgery Congress (http://www.myisem.org/robert-zhong-award.php) 2009 Outstanding Ph.D. Invited Lecturer at University of Western Australia 2012 Shanghai Graduate Student Outstanding Achievements (Thesis) Award (sole recipient from PhD program.) 2012 Investigator Award from Plastic Surgery Foundation 2016 MD Anderson Excellent Job Performance Award 2019 MD Anderson Excellent Job Performance Award PROFESSIONAL MEMBERSHIPS/ACTIVITIES: 2009-present: Steering member, International Society for Experimental Microsurgery 2011-2014: Principal investigator, member, Plastic Surgery Foundation 2019-present: Member, Society of Clinical Research Associates (SOCRA) 2009-present: Reviewer of Annals of Plastic Surgery, Microsurgery, International Journal of Dermatology PUBLICATIONS: 1. Yang M, Li QF, Liang YM, Weng R, Li H. Skin regeneration: What determines it?. Med Hypotheses. 2009, Apr; 72(4): 475-6. Cited in PubMed; PMID: 19121559. 2. Zan T, Dong JY, Li H, Weng R, Yang M, Xie Y, Li QF. Comparison of the effect of local administration of endothelial progenitor cells and VEGF on improving neovascularization in flap prefabrication. Chin J Plast Surg. 2009, Nov; 25(6): 451-5. Cited in PubMed; PMID: 20209939. Pub Status: Published. 3. Yang M, Li QF, Zhang F. HOX genes in the skin. Chinese Medical Journal. 2010, Sep; 123(18): 2607-2612. Cited in PubMed; PMID: 21034636. Pub Status: Published. 4. Yang M, Sheng L, Li H, Weng R, Li QF. Improvement of the skin flap survival with the bone marrow-derived mononuclear cells transplantation in a rat model. Microsurgery. 2010, May; 30(4): 275-81. Cited in PubMed; PMID: 20309852. Pub Status: Published. 5. Weng R, Li Q, Li H, Yang M, Sheng L. Mimic hypoxia improves angiogenesis in ischaemic random flaps. J Plast Reconstr Aesthet Surg. 2010, Dec; 63(12): 2152-9. Cited in PubMed; PMID: 20359971. Pub Status: Published. 6. Li H, Zan T, Li Y, Weng R, Yang M, Du Z, Zhong S, Li Q. Transplantation of adipose-derived stem cells promotes formation of prefabricated flap in a rat model. Tohoku J Exp Med. 2010, Oct; 222(2): 131-40. Cited in PubMed; PMID: 20944441. Pub Status: Published. 7. Yang M, Rawson JL, Zhang EW, Arnold PB, Lineaweaver W, Zhang F. Comparisons of Outcomes from Repair of Median Nerve and Ulnar Nerve Defect with Nerve graft and Tubulization: A Meta-analysis. J Reconstr Microsurg. 2011, Oct; 27(8): 451-60. Cited in PubMed; PMID: 21796581. Pub Status: Published. 8. Yang M, Liang Y, Sheng L, Shen G, Liu K, Gu B, Meng F, Li Q. A preliminary study of differentially expressed genes in expanded skin and normal skin: implications for adult skin regeneration. Arch Dermatol Res. 2011, Mar; 303(2): 125-33. Cited in PubMed; PMID: 21286735. Pub Status: Published. 9. Sheng L, Yang M, Li H, Du Z, Yang Y, Li Q. Transplantation of adipose stromal cells promotes neovascularization of random skin flaps. Tohoku J Exp Med. 2011, Jul; 224(3): 229-34. Cited in PubMed; PMID: 21701129. Pub Status: Published. 10. Yang M, Zhang F, Sailes FC, Zhang EW, Lin S, Das SK. Role of Anti-TNF-a Therapy in Fat Graft Preservation. Ann Plast Surg. 2012, May; 68(5): 531-5. Cited in PubMed; PMID: 21629060. Pub Status: Published. 11. Yan H, Yang M, Lineaweaver WC, Myers RS, Chen H, Zhang F. Flap Reconstruction of Distal Lower Extremity Wounds in Diabetic Patients. Ann Plast Surg. 2011, Oct; 67(4): 426-8. Cited in PubMed; PMID: 21508815. Pub Status: Published. 12. Yang M, Li Q, Sheng L, Li H, Weng R, Zan T. Bone Marrow-derived Mesenchymal Stem Cells Promote Skin Regeneration On a Skin Expansion Model Through Epidermal Growth Factor Paracrine Secretion. Annals of Surgery. 2011, Jan; 253(1): 202-209. Cited in PubMed; PMID: 21508815. Pub Status: Published. 13. Yang M, Angel MF, Pang Y, Angel JJ, Wang Z, Neumeister MW, Wetter N, Zhang F. Expression of Inducible Nitric Oxide Synthase in Muscle Flaps Treated with Ischemic Postconditioning. HAND. 2012, Sep; 7(3): 297–302. Cited in PubMed; PMID: 23997736. Pub Status: Published. 14. Sheng L, Yang M, Du Z, Yang Y, Li Q. Transplantation of stromal vascular fraction as an alternative for accelerating tissue expansion. J Plast Reconstr Aesthet Surg. 2013, Apr; 66(4): 551-7. Cited in PubMed; PMID: 23245918. Pub Status: Published. 15. Lough D, Dai H, Yang M, et al.. Stimulation of the follicular bulge LGR5+ and LGR6+ stem cells with the gut-derived human alpha defensin 5 results in decreased bacterial presence, enhanced wound healing, and hair growth from tissues devoid of adnexal structures. Plast Reconstr Surg. 2013, Nov; 132(5): 1159-71. Cited in PubMed; PMID: 24165598. Pub Status: Published. 16. Derby BM, Dai H, Reichensperger J, Cox L, Harrison C, Cosenza N, Yang M, Bueno RA, Neumeister MW. Adipose-derived stem cell to epithelial stem cell transdifferentiation: a mechanism to potentially improve understanding of fat grafting\'s impact on skin rejuvenation. Aesthet Surg J. 2014, Jan; 34(1): 142-53. Cited in PubMed; PMID: 24334307. Pub Status: Published. 17. Yang M, Sheng L, Zhang TR, Li Q. Stem Cell Therapy for Lower Extremity Diabetic Ulcers: Where Do We Stand?. Biomed Res Int. 2013, Mar; 2013(2013): 462179. Cited in PubMed; PMID: 23586040. Pub Status: Published. 18. Sheng L, Yang M, Liang Y, Li Q. Adipose tissue-derived stem cells (ADSCs) transplantation promotes regeneration of expanded skin using a tissue expansion model. Wound Repair Regen. 2013, Sep; 21(5): 746-54. Cited in PubMed; PMID: 23937682. Pub Status: Published. 19. Yu Q, Sheng L, Yang M, Zhu M, Huang X, Li Q. Tanshinon IIA injection accelerates tissue expansion by reducing the formation of the fibrous capsule. PLoS One. 2014, Aug; 9(8): e105756. Cited in PubMed; PMID: 25157742. Pub Status: Published. 20. Lough DM, Yang M, Blum A, et al.. Transplantation of the LGR6+ Epithelial Stem Cell into Full-Thickness Cutaneous Wounds Results in Enhanced Healing, Nascent Hair Follicle Development, and Augmentation of Angiogenic Analytes. Plast Reconstr Surg. 2014, Mar; 133(3): 579-90. Cited in PubMed; PMID: 24572851. Pub Status: Published. 21. Schmucker RW, Mendenhall SD, Reichensperger JD, Yang M, Neumeister MW. Defining the Salvage Time Window for the Use of Ischemic Postconditioning in Skeletal Muscle Ischemia Reperfusion Injury. J Reconstr Microsurg. 2015, Oct; 31(8): 597-606. Cited in PubMed; PMID: 26165885. Pub Status: Published. 22. Zhou SB, Zhang GY, Xie Y, Zan T, Gan YK, Yao CA, Chiang CA, Wang J, Liu K, Li H, Zhou J, Yang M, Gu B, Xie F, Pu LQ, Magee WP 3rd, Li QF. Autologous Stem Cell Transplantation Promotes Mechanical Stretch Induced Skin Regeneration: A Randomized Phase I/II Clinical Trial. EBioMedicine. 2016, Nov; 13(13): 356-364. Cited in PubMed; PMID: 27876353. Pub Status: Published. 23. Wei J, Herrler T, Liu K, Han D, Yang M, Dai C, Li Q. The Role of Cell Seeding, Bioscaffolds, and the In Vivo Microenvironment in the Guided Generation of Osteochondral Composite Tissue. Tissue Eng Part A. 2016, Dec; 22(23): 1337-1347. Cited in PubMed; PMID: 27806676. Pub Status: Published. 24. Wei J, Herrler T, Gu B, Yang M, Li Q, Dai C, Xie F. Large-Scale Skin Resurfacing of the Upper Extremity in Pediatric Patients Using a Pre-Expanded Intercostal Artery Perforator Flap. J Craniofac Surg. 2018, May; 29(3): 562-565. Cited in PubMed; PMID: 29485566. Pub Status: Published. Peer Reviewed Book Chapter Mei Yang, Qingfeng Li.. (2012). Stem cell, regenerative medicine and cancer Chapter: Cell Transplantation: New Research. In D. J. Belgaris and A. N. Savarese (Ed.), Cell Transplantation (pp. 89-103). New York: Novapublishers.com. Qingfeng Li, Mei Yang. (2012). Stem cell research: a New Era for Reconstructive Surgery. In Stefan Danilla (Ed.), Selected Topics in Plastic Reconstructive Surgery (pp. 163-174). London: Intech - open access publisher.