Robson Faria

Oswaldo Cruz Institute

Robson Faria received his degree in Biological Sciences (2001) from the Federal University of Rio de Janeiro and M.Sc. (2003) and D.Sc. (2006) from the Oswaldo Cruz Foundation’s Cellular and Molecular Biology program. He has been a Public Health Researcher at the Oswaldo Cruz Foundation since 2007. During the past 15 years, Dr. Robson has been working with the purinergic receptors, especially P2X7R, and the action of synthetic molecules and derivatives of natural products to discover new prototypes capable of treating neglected diseases.

1books edited

3chapters authored

Latest work with IntechOpen by Robson Faria

This book aims to provide a brief update on the functions of purinergic receptors in various systems, in addition to the signaling pathway activated to mediate these functions. We address the influence of hypoxia by modulating the activity of these receptors under physiological and pathophysiological conditions. Additionally, we describe the mechanisms of induction of pain and inflammation in different systems. Finally, the book discusses some of the main bioinformatics tools currently used to improve or discover new prototypes capable of selectively acting on these receptors with estimated parameters of satisfactory solubility and toxicity for possible commercial implementation.

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