Hiroyuki Shimada

Hiroyuki Shimada, MD, PhD, FRCPA (Hon) currently works as a Pathologist in the Department of Pathology & Laboratory Medicine, Children\'s Hospital Los Angeles and as a Professor at the University of Southern California Keck School of Medicine, Los Angeles, California in USA. He is also engaged as the Pathologist-of-Record for the Children\'s Oncology Group, Neuroblastoma Biology Study, and as Chair of the International Neuroblastoma Pathology Committee. He was born in Tokyo, Japan (1948), graduated from Yokohama City University School of Medicine, Yokohama, Japan (1973) and completed Pathology Training at the Children\'s Hospital and the Ohio State University, Columbus, Ohio, USA (1988). He is a founder of the International Neuroblastoma Pathology Classification (1999). He is actively reviewing pathology samples of about 700 neuroblastoma cases per year from United States, Canada, Australia, and New Zealand.

2books edited

Latest work with IntechOpen by Hiroyuki Shimada

Neuroblastoma, once called "enigmatic", due to "unpredictable" clinical behaviors, is composed of biologically diverse tumors. Molecular/genomic properties unique to the individual tumors closely link to the clinical outcomes of patients. Establishing risk stratification models after analyzing biologic characteristics of each case has made a great success in patient management. However, the trend of improving survival rates in neuroblastoma over the last 30 years has started to level off, and currently available treatment modalities have almost reached to their maximized intensity. Furthermore, aggressive treatment causes significant long-term morbidities to the survivors. We really need to make the next step to the level of personalized medicine with more precise understanding of neuroblastoma biology. This book includes useful data and insights from the world's experts in this field. I believe this book can make an excellent contribution to all the investigators working hard and fighting for the children stricken by this disease.

Go to the book