Biography and the Research Achievements: After graduating from Faculty of Veterinary Science, Chulalongkorn University for D.V.M. degree in 1969, Professor Narongsak Chaiyabutr joined Faculty of Veterinary Science, Chulalongkorn University as an instructor in the Department of Physiology. He obtained M.S. degree in Physiology for his further study from Mahidol University in 1971. He has postgraduate training in Animal Physiology and Biochemistry under FAO fellowship at The Royal of Veterinary and Agricultural University, Denmark between 1971-1973. Later in 1978 he obtained a grant from Chulalongkorn University for his Ph.D study in U.K. In 1980, he was awarded the degree of Doctor of Philosophy from Glasgow University, Scotland, U.K. for a thesis entitled Control of Mammary function during Pregnancy and Lactation in the Goat: Effects of Starvation. His study in Nutrition Physiology discipline was conducted under the supervision of Professor Dr. Malcolm Peaker and Dr. Anne Faulkner at the Hannah Research Institute. Professor Chaiyabutr has been involved in teaching and research conducting both the undergraduate and graduate levels. He was appointed Professor in Animal Physiology in 1992. The focus of Professor Chaiyabutr’s research was to study on the field of animal physiology relating to agricultural science and biomedical science disciplines. Professor Chaiyabutr published papers in refereed journals nearly 200 scientific papers, reviewed many research papers and reports and he has been invited to attend and give presentations at many international meeting and conferences in Asia and other part of the world (these are listed in the attachment). From his research outputs, Professor Chaiyabutr set himself the task of gaining professional recognition nationally and internationally for not only the animal scientist but medical scientist in general. He was very much responsible for the creation of new scientific works on the physiology discipline not only in the area of animal science but also related to medical science. With his contributions and international recognition, Professor Chaiyabutr received the Distinguished Researcher Awards (Animal Production) at 6th Asian-Australasian Association of Animal Production Society (AAAP) Congress, November, 1992, Bangkok, Thailand. In 1995, he received the National outstanding researcher awards (Agriculture and Biology) by National Research Council of Thailand. In 1998, he received Distinguished Veterinarian Awards (Academic discipline) by The Veterinary Medical Association of Thailand. In 2002, he received Outstanding Research Awards, Rachadapiseksompoj Fund, Chulalongkorn University, The area of research for animal physiology including veterinary science and animal science, in this field, Professor Chaiyabutr played a leading role in the studying in the field of environmental physiology. He observed that the stress of hot environments lowered productive efficiency in livestock both direct and indirectly in tropical condition. The study started by investigation the effect of heat stress on the changes in bodily functions of domestic animals in the tropic by using buffalo as a modeling animal. Buffalo is the animal with the greatest potential for development in the tropical country. Since buffalo population in Asia is declining in quantity and quality due to social, political and technical problem. It would be very important to assess the potential impact that could be achieved through research and development on this subject. Buffalo is a low heat tolerance animal with low sweating glands and the knowledge of physiology and biochemistry for buffalo get scant attention in all textbook. The study on responses of bodily functions during both acute and prolonged heat exposure have revealed multifacets involving many systems in the body. The body’s responses of buffalo to heat stress are interpreted as defense mechanisms. These defenses have important physiological consequences in terms of changes in cardio-respiratory functions, body water regulation, distributions of body fluids compartments and blood compositions. During heat stress, the regulation of kidney functions and changes in hormonal system are also involved. The research findings lead to better understand of mechanism for thermo-regulation in domestic animals. The scope of this research work clearly contributed to advanced knowledge, pioneering and covers animal physiology not only for the benefit in development of livestock production in the country but also for other tropical countries. Professor Chaiyabutr has also been contributing the scientific work on dairy science. His research study involved physiology of the mammary gland and milk secretion in both dairy goat and crossbred dairy cattle in the tropic. He observed that the low milk yield and short lactation period of either pure exotic or crossbred dairy cattle was a major problem for the Thai dairy practices. The rapid decrease in milk yield after peak lactation in dairy cattle has long been a biological conundrum for the mammary biologist, as well as a cause of considerable lost income for the dairy farmer. The genetic potential for milk production of most indigenous cattle in the tropics is less than that of dairy cattle in temperate countries, while indigenous cattle have resistance to many tropical diseases and a high level of heat tolerance. Crossbreeding has been exploited as an efficient tool for blending the adaptability of tropical cattle with the high milking potentials of exotic breeds for increase milk production. Several researches have been attempted to try to improve dairy productivity. There is still a need to identify the type of crossbred cattle that are the most suitable for the tropics. The mechanism acting within the body to limit the rate of milk yield and shorter lactation persistency as lactation advances in crossbred dairy cattle is unknown. The problems of dairying in the tropics are multifaceted including nutrition, the hot climate, genetics, disease and management. Many factors affect milk production in dairy cattle in tropical areas including high environmental temperature and humidity, lower genetic potential for milk production in indigenous cattle and inadequate supply of food during the dry and hot summer season. To understand the mechanism acting within the body in relation to the control of milk secretion and improve of milk production in crossbred dairy cattle in tropics, series of studies were investigated for factors affecting various physiological changes on the mechanism responsible for the control of the mammary function (extra-mammary functions) and the process of milk synthesis (intra-mammary functions) in different stages of lactation. The study in different types of crossbred cattle demonstrate that the regulation of biosynthetic capacity within the mammary gland would be influenced more by local than by systemic factors. An estimation in vivo for the utilization of glucose shows different proportion of glucose metabolized less for lactose synthesis, but metabolized more via the Embden-Meyerhof pathway and the tricarboxylic acid cycle as lactation advances in crossbred cattle containing low genetic of exotic Bos taurus breed. Dairy research projects were conducted under funded by The Thailand Research Fund, i.e. a) Comparative study on the regulation of milk secretion in crossbred Holstein cattle feeding on different types of roughages. b) Control mechanisms for milk secretion during the lactating periods in crossbred Holstein cattle: role of growth hormone. c) Physiological responses of lactating crossbred Holstein cattle to high ambient temperature and control mechanisms to reduce its effect on milk production. Professor Chaiyabutr was responsible furthermore for the creation a knowledge of physiology involving medical science. The physiological field experience led him to do the research work related to medical science that acute renal failure in patient with snake bite particularly Russell’s viper snake, is a result of medical problem. Lack of knowledge for pathophysiology of acute renal failure during envenomation was apparent. Professor Chaiyabutr recognized the need to do research which takes into account the context in which the problem arises. An approach study with collaboration with Faculty of Medicine, CU for study the effect of Russell’s viper venom on kidney function in experimental animals was then launched since 1982. From this study, it was learned that acute renal failure is an important complication during envenomation by Russell’s viper. Alterations in cardiovascular system and renal hemodynamics were observed in envenomated animals. Two phases of changes in hemodynamics were reported. The effects of the venom on renal hemodynamics are complex. The mechanism for the release of mediators in the circulation during envenomation seems to be involved in activation of renal failure. The role of mediators on bodily functions have been extensively investigated. However, the study is being performed. His pioneering and covers physiological science are reflected in his research and the work through basic science to this society.