Steve W. Kerrigan

Molecular And Cellular Therapeutics Royal College Of Surgeons

Prof. Steve Kerrigan is Associate Professor of Pharmacology in the School of Pharmacy in RCSI and Head of the Cardiovascular Infection Research Group which is part of the Irish Centre of Vascular Biology.Prof. Steve Kerrigan is an honours graduate in B.Sc Pharmacology from King's College University of London, UK and obtained an M.Sc in Immunopharmacology from the University of Strathclyde, Glasgow, Scotland. He received a PhD in Cardiovascular Infection specifically investigating platelet-bacterial interactions from RCSI in 2001. Following this he carried out postdoctoral research in the University of California, San Francisco, USA. Prof. Kerrigan was appointed lecturer in Pharmacology in the School of Pharmacy in 2008, promoted to Senior Lecturer in 2013 and Associated Professor in 2017. Prof. Kerrigan is a member of more than 10 international societies and was elected to Chartered status (CBiol) and Fellowship of the Society of Biology (FSB) which are the highest grades of membership of the professional body in 2013. Prof. Kerrigan is currently co-chair of the International Society for Thrombosis and Haemostasis Scientific Standardization Committee in Biorheology.

2books edited

4chapters authored

Latest work with IntechOpen by Steve W. Kerrigan

Endocarditis is an inflammation of the lining of the heart and valves. It can be due to a non-infectious cause but when the inflammation is associated with an infection, usually bacterial, it is known as infective endocarditis. It is typically characterized by the development of a large septic thrombus on one of the cardiac valves. As this thrombus grows, it can lead to valve failure or may fragment forming a septic embolus that is associated with high mortality if the target of the embolus is the brain, heart or lung. This book reviews multi-organ complications associated with Infective endocarditis including significant recent advances in molecular mechanisms underlying thrombus formation on the cardiac valve, anti-microbial treatment and surgery.

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