Allergies are complex inflammatory diseases with a not fully understood etiology. Several factors, including genetic, environmental, age of exposition, diet, etc., are associated with the induction of these diseases. The incidence of allergies has increased during the last decades and constitutes the most common immune-based disease worldwide. According to the hygiene hypothesis, a lower exposure to pathogens and commensal microbes that reside in the intestinal lumen is responsible for the rapid rise of the prevalence of atopic and allergic disorders, specifically food allergy. To overcome this tendency, the immunological mechanisms underlying this pathology should be better understood, which will undoubtedly impact the development of novel therapies. A large body of evidence demonstrates that immunotherapies constitute corrective treatments of the impaired regulation of the immune system in allergic patients.
Part of the book: Milk Proteins