Svetlana P. Chapoval

Dr. Svetlana Chapoval completed her medical training in 1985 at Russian State Medical University and PhD training in 1994 at Gamaleya Scientific Research Institute of Epidemiology and Microbiology. She then completed her postdoctoral fellowship in Immunology at Mayo Clinic in 2002. From 2002 to 2005 Dr. Chapoval was an Associate Research Scientists in the Department of Pulmonary and Critical Care Medicine at Yale University. She joined the Center for Vascular and Inflammatory Diseases and the Program in Oncology of the University of Maryland Marlene and Stewart Greenebaum Cancer Center at University of Maryland School of Medicine in 2006 as an Assistant Professor. Dr. Chapoval’s research is focused on cellular and molecular mechanisms of lung chronic inflammatory diseases, asthma in particular, and novel molecules for disease immunotherapy. She is well-recognized for her work on HLA Class II-restricted allergen T cell epitopes, VEGF-induced lung DC modifications, and her recent discoveries on neuroimmune semaphorins 4A and 4D contributions to allergic airway inflammation and to Treg cell phenotype and function. Dr. Chapoval has served and continue to serve as a reviewer for 20+ peer-reviewed scientific journals. In 2015, she completed a 4-year term as an Associate Editor for a renowned journal.

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3chapters authored

Latest work with IntechOpen by Svetlana P. Chapoval

Since their discovery in 1973 by Zanvil Cohn and Ralph Steinman (Nobel Prize in Physiology and Medicine, 2011), dendritic cells (DCs) continue to intrigue research scientists as their new markers, subpopulations and properties are being detected and the relevant literature is being doubled each year. This book combines the most comprehensive reviews of several critical aspects of DC biology and function written by a group of international experts in the field. The first section briefly discusses recent advances in DC subtypes, phenotypes, and functions in different diseases. The following sections look closely at DC phenotyping, DC-NK cell interplay, and roles of DC in bone loss and repair and parasitic infections. The final section on DC and cancer includes perspectives on DC vaccination based on modifications and therapeutic applications.

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