Medical doctor Mario Francisco Juruena graduated from Pontifical Catholic University of Rio Grande do Sul (RS), Southern Brazil. He did his residency training in psychiatry at the Sao Pedro Psychiatric Hospital, and completed interdisciplinary course for specialization in mental health in School of Public Health of the RS / Porto Alegre-RS. He received his first master\'s degree at the Department of Psychobiology, Federal University of São Paulo, and the second in affective neuroscience, Universiteit Maastricht, the Netherlands. Finally, he received his doctorate (PhD in Psychiatry) at University of London and Post-doctoral fellowship at the Institute of Psychiatry at King\'s College London, United Kingdom. He is a specialist in adult psychiatry in the UK according to the specialist training authority of the Medical Royal Colleges and General Medical Council (GMC). He also completed training in cognitive psychotherapy at Beck Institute for Cognitive Therapy and Research. He has published over 80 original research articles, reviews and book chapters, and edited four books. The vast majority of his studies is related to the pathophysiology, diagnosis and treatment of affective disorders; depression, bipolar and its relationship to stress. He is currently the Associate Editor of BioMed Central (BMC) Psychiatry-UK and a member of the Editorial Board as well as the reviewer of dozens of high-impact international periodicals. He has been invited as a speaker in numerous international conferences such as British Association for Psychopharmacology that awarded him \The Senior Clinical Psychopharmacology Award 2007\. He also received the Robert W. Psychopharmacology Kerwin Prize in 2010 from the Royal College of Psychiatrists for the best article published on the subject in the British Journal of Psychiatry. He is currently a Professor at the Department of Neurosciences and Behavior, University of São Paulo (USP-FMRP) and Honorary Senior Lecturer at the Institute of Psychiatry, Kings College London.