Raghvendra Dubey

University Hospital of Zurich Switzerland

Dr. Raghvendra K Dubey is currently Professor at the Clinic for Reproductive Endocrinology, University Hospital Zurich. His main Research topic is to study the Role of Sex Hormones in Various Pathophysiologies with specific relevance to womens Health. He has published more than 100 original peer reviewed original papers and several reviews and book chapters. He is fellow of AHA and physiological societies and held a joint associate professorship since 1996 -2010 at the Center for Clinical Pharmacology, Department of Medicine, University of Pittsburgh Medical Center, USA. He has several Patents on Investigative Therapeutic Molecules and has had research funding for the last 2 decades. He has had several PhD and masters students both at ETH Zurich, (Switzerland) and University of Pittsbuurgh (USA).

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Latest work with IntechOpen by Raghvendra Dubey

Sex Hormones not only regulate reproductive function, but they also play a prominent role in the biology and physiology of several organs/tissues and in the pathophysiology of several diseases. During the last two decades, the information on the mechanisms of action of sex hormones, such as estrogens and androgens, has rapidly evolved from the conventional nuclear receptor dependent mechanisms to include additional non-nuclear, non-genomic and receptor-independent mechanisms. This highlights the need to update the current knowledge on sex hormones and their mode of action. Increasing evidence that exogenous/epigenetic factors can influence sex hormone production and action highlights the need to update our knowledge on the mechanisms involved. This book provides a systematic and updated overview of the male/female sex-hormones and their impact in the biology and physiology of various organs. Additionally, the book discusses their positive and negative association with the pathophysiology of various diseases (e.g. osteoporosis, cardiovascular-disease, hypogonadism, reproduction, cancer) and their therapeutic potential.

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