Vlad Alexandrescu

Born in 1958, Dr. Alexandrescu graduated at the Leuven Medical University (UCL, Saint-Luc University) in Brussels in 1994 (with honorary distinction).Adding further to postgraduate stages, he acquired complementary endovascular skills (particularly in carotid, aortic, and below-the-knee peripheral revascularizations) in Saint Joseph Hospital in Marseille (Pr. P. Bergeron and Pr. J. Jausseran), France, and earned particular experience in lower limb CTO recanalization techniques in Leicester Royal Infirmary (Professors P. R. Bell and N. J. London, Vascular Dept. University of Leicester), UK.

1books edited

2chapters authored

Latest work with IntechOpen by Vlad Alexandrescu

Outstanding scientific advances over the last decades unceasingly reveal real complexity of wound-healing process, astonishing in its staged progression, as life is unfolding itself. This natural course of tissue repair seems to bear thousands of overlapping molecular and macroscopic processes that nowadays only start to unfold to our knowledge. The present volume collecting recent scientific references proposes to readers a two-folded audacious goal. First, an updated design of intimate cellular mechanisms is entailed in tissue regeneration that emanates from the first section of the book. Next, a multidisciplinary therapeutic perspective that focuses on macroscopic healing throughout the second part of this work adds clinically integrated observation. Practical diagnostic and treatment information is appended in each chapter that may equally help experienced clinicians or dedicated students and researchers in broadening essential breaking points of their work. It is the wish of all multidisciplinary experts who gather prominent author's panel of this volume to incorporate latest medical reports and compel limits of current understanding for better tissue regeneration, limb salvage, and improved quality of life of our patients.

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Wound HealingNew insights into Ancient ChallengesEdited by Vlad Alexandrescu

Wound Healing

Edited by Vlad Alexandrescu

Chapters authored

Is Limb Loss Always Inevitable for Critical Neuro-Ischemic Foot Wounds in Diabetic Patients with End Stage Renal Disease and Unfit for Vascular Reconstructions?

By Vlad Alexandrescu

Part of the book: Diseases of Renal Parenchyma

Ischemic Ulcer Healing: Does Appropriate Flow Reconstruction Stand for All That We Need?

By Vlad-Adrian Alexandrescu and François Triffaux

During the recent decades, soaring progresses in vascular disease knowledge, particularly in critical limb ischemia (CLI) treatment, enhanced novel diagnostic and interventional strategies with high serviceableness in patient’s selection, arterial recanalization, and dedicated ischemic ulcer follow-up. However, despite undeniable advances in medical technology and clinical judgment, limb salvage, the ambulation recovery, and patient’s survival seem only scarcely affected in this heterogeneous CLI group, particularly concerning the diabetic and renal patients. Innovative strategies such as “end artery occlusive disease” treatment or “wound-targeted revascularization” were equally proposed by following the angiosomal anatomical distribution associating individual foot collateral assessment in a unified macro- and micro-circulatory judgment. However, despite encouraging clinical results, prospective evidence still lacks on this concern. It also appears that specific wounds could not always stand for the lowest perfusion areas according to current CLI criteria, since severe neuropathy, inflammatory swelling, local infection, and skin trauma may add complementary hindrances to tissue viability.

Part of the book: Wound Healing

Vlad Alexandrescu

Latest work with IntechOpen by Vlad Alexandrescu

Wound Healing

Chapters authored

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