My expertise is in the Immunology of infectious Diseases in particular humoral and cellular immunology. Since my doctoral studies I have been unraveling the immunological status of infection and uninfected individuals living in endemic communities. In particular this has been for Schistosomiasis, malaria and soil transmitted helminths. For schistosomiasis I have been studying the T cell characteristics in the infected comparing to counterparts who are resistant to infection. Also I have been studying the underlying causes of resistance and susceptibility to infection and re-infection. Due to failure to come up with effective vaccines against schistosomiasis and other neglected tropical diseases finally mapped country distribution of infection and recommended appropriate chemotherapeutic approach using mass drug administration by the Ministry of Health.