Jaime Bustos-Martínez

Universidad Autónoma Metropolitana Mexico

Dr. Jaime Bustos-Martínez is a Research Professor at the Universidad Autónoma Metropolitana-Xochimilco, in Mexico City, Mexico. He has a degree in biological pharmaceutical chemistry, an MSc in biochemical sciences and a Ph.D. in biomedical sciences. For more than 20 years he has been studying virulence factors, molecular epidemiology and nanoparticles against Staphylococcus aureus. His studies have been published in several articles in indexed journals and have been presented in international forums. His publications include several textbook chapters and he is a reviewer for multiple journals. He is part of Mexico’s National System of Researchers.

1books edited

3chapters authored

Latest work with IntechOpen by Jaime Bustos-Martínez

The study of staphylococci has a long way to go, due to the great significance both for humans and for dairy or companion animals of their large number of virulence factors. Their resistance to antibiotics makes these microorganisms become highly pathogenic species that can cause infections ranging from mild to fatal. Staphylococci, especially S. aureus and strains resistant to methicillin (MRSA), are among the most studied microorganisms worldwide. This book covers recent advances in the study of staphylococci. The book is divided into four sections that cover four important events for the study and combat of staphylococci: colonization, epidemiology and pathogenesis, diagnosis, and new treatments. Staphylococci can present a broad spectrum of resistance to antibiotics, which is why their elimination has become difficult. The final section of the book is devoted to new compounds for the fight against staphylococci. We hope that the information contained in this book will be useful for the study and investigation of these medically important microorganisms.

Go to the book

Staphylococcal Infections

Edited by Jaime Bustos-Martínez

Chapters authored

Urinary Tract Infections in Psychiatric Patients

By Teresita Sáinz Espuñes, Maria Elisa Drago Serrano and Jaime Amadeo Bustos Martínez

Part of the book: Urinary Tract Infections

Factors of Nasopharynx that Favor the Colonization and Persistence of Staphylococcus aureus

By Samuel González-García, Aída Hamdan-Partida, Anaíd Bustos-Hamdan and Jaime Bustos-Martínez

Between 30 and 50% of the world population is permanently colonized in some anatomical site by Staphylococcus aureus, although the vast majority are asymptomatic carriers. The nose is its main niche and currently the colonization of S. aureus in the pharynx has become relevant due to the variety of reported carrier rates and the epidemiological importance of the dissemination of Methicillin-resistant S. aureus strains (MRSA) by pharyngeal carriers. For this bacterium to colonize a tissue successfully, it is necessary to establish many interactions with bacterial and host cell components such as bacterial wall teichoic acids (WTA) with the Scavenger SREC-1 host receptor and at the same time evade the defense mechanisms. On the other hand, there are host factors that will facilitate or complicate the colonization or persistence of S. aureus at these sites, such as physiological, genetic, immunological and microbiological factors.

Part of the book: Pharynx

Main Factors of Staphylococcus aureus Associated with the Interaction to the Cells for Their Colonization and Persistence

By Samuel González-García, Aída Hamdan-Partida, Juan José Valdez-Alarcón, Anaid Bustos-Hamdan and Jaime Bustos-Martínez

Staphylococcus aureus is a microorganism that can colonize the nose, pharynx, and other regions of the body. It has also been observed that it can cause persistence. Successful colonization of S. aureus depends in the factors that favor the interaction of the bacteria with host cells. The bacterial determinants of S. aureus that have the capacity to adhere to human tissues involve adhesion factors such as teichoic acids and cell-wall-anchored proteins (CWA) such as ClfA, IcaA, SdrC, FnBPA, among others. The colonization and persistence process first involve adhesion to the tissue, followed by its reproduction and the possible formation of a biofilm. This review will describe the main virulence factors that allow bacterial adhesion and biofilm formation, including the accessory gene regulator genes (agr), related to colonization and persistence of S. aureus.

Part of the book: Staphylococcal Infections

Jaime Bustos-Martínez

Latest work with IntechOpen by Jaime Bustos-Martínez

Staphylococcal Infections

Chapters authored

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