Alberto Sandri

By Pier Luigi Filosso, Alberto Sandri, Enrico Ruffini, Paolo Olivo Lausi, Maria Cristina Bruna and Alberto Oliaro

Part of the book: Melanoma in the Clinic

By Alberto Sandri, Alessandro Maraschi, Matteo Gagliasso, Carlotta Cartia, Roberta Rapanà, Simona Sobrero, Federica Massa, Luisella Righi and Francesco Ardissone

Solitary fibrous tumours of the pleura (SFTP) are rare neoplasms originating from one of the components of the sub-mesothelial connective layer underlying the pleura. They are the most common non-mesothelial primary pleural neoplasms but still remain relatively rare. Their behaviour is mostly indolent; however, some may de-differentiate into malignant and aggressive tumours. Surgical resection is the mainstay treatment for SFTP, even more so in case of voluminous masses, due to compression onto lung, mediastinum and great vessels. In this chapter, we discuss the disease characteristics reported in the literature with respect to clinical presentation, diagnosis and treatment; also, we will discuss the results of patients treated for SFTP who underwent a surgical treatment in our unit of thoracic surgery.

Part of the book: Diseases of Pleura

By Alberto Sandri and Francesco Leo

Part of the book: Pleura

By Simona Sobrero, Francesco Leo and Alberto Sandri

Although less frequent than the primary spontaneous pneumothorax (PSP), secondary pneumothoraces (SP) are a common clinical problem with a wide range of severity, depending on the triggering cause(s) and patient clinical condition. By definition, an SP occurs in those patients with an underlying condition that alters the normal lung parenchyma and/or the visceral pleura and determines air entry in the pleural space (e.g., COPD) or, eventually, following trauma or invasive procedures (i.e., iatrogenic pneumothorax). Less frequent, yet described, is SP occurring in neoplastic patients or infectious ones. The gravity of an SP is directly correlated to the underlying cause and patients’ clinical conditions. For example, it may be a life-threatening condition in an end-stage COPD but less severe in a catamenial related syndrome. In this chapter, we are providing a surgical overview of the most relevant and updated information on etiology, incidence, pathophysiology, and management of secondary pneumothoraces.

Part of the book: Pleura