Davide Schiffer

By Davide Schiffer, Laura Annovazzi, Valentina Caldera and Marta Mellai

Part of the book: Management of CNS Tumors

By Marta Mellai, Valentina Caldera, Laura Annovazzi and Davide Schiffer

Part of the book: Evolution of the Molecular Biology of Brain Tumors and the Therapeutic Implications

By Davide Schiffer, Consuelo Valentini, Antonio Melcarne, Marta Mellai, Elena Prodi, Giovanna Carrara, Tetyana Denysenko, Carola Junemann, Cristina Casalone, Cristiano Corona, Valentina Caldera, Laura Annovazzi, Angela Piazzi, Paola Cassoni, Rebecca Senetta, Piercarlo Fania and Angelina Cistaro

Part of the book: Tumors of the Central Nervous System

By Davide Schiffer, Marta Mellai, Laura Annovazzi, Cristina Casalone and Paola Cassoni

Part of the book: Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor

By Marta Mellai, Laura Annovazzi, Marta Mazzucco and Davide Schiffer

Oligoastrocytoma (OA) was a glioma recognized in the current World Health Organization (WHO) classification of the central nervous system (CNS) tumors as a mixed tumor with an astrocytic and an oligodendroglial component. Its definability was, however, poor so that its prevalence varies in the various collections. A series of contributions of the literature and the “International Society of Neuropathology (ISN) – Haarlem Consensus” recently denied its existence as a tumor entity on the basis of 1p/19q, isocitrate dehydrogenase (IDH) and α-thalassemia/mental retardation syndrome X-linked (ATRX) status. Most tumors previously diagnosed as OAs were, therefore, reclassified as either oligodendrogliomas or astrocytomas.

Part of the book: Neurooncology