Paula Bubulya

Wright State UniversityUnited States of America

Paula A. Bubulya, Ph.D., is an Associate Professor in the Department of Biological Sciences at Wright State University in Dayton, Ohio, USA where she has been employed since 2005. She received her Ph.D. in Biological Sciences from the University of Toledo in Toledo, Ohio in 1998 for her dissertation on cadherin-catenin interactions in adherens juctions. She was a postdoctoral fellow studying cell biology, nuclear organization and microscopy at Cold Spring Harbor Laboratory from 1999-2005. Dr. Bubulya currently teaches both undergraduate and graduate courses in Cell Biology at Wright State University. In line with her passion for involving students in laboratory research, Dr. Bubulya’s research team at Wright State University is comprised primarily of undergraduate, M.S. and Ph.D. students. Members of the lab study the connection between gene expression and nuclear organization in mammalian cells, and they gain expertise in cellular imaging and in situ approaches to examine gene expression. The long-term goal of Dr. Bubulya’s research program is to determine how nuclear domains called nuclear speckles organize into discrete yet dynamic nuclear domains, how key components of nuclear speckles help to coordinate pre-mRNA transcription and processing, and how the function of speckle components impacts mitosis. Dr. Bubulya’s research is funded by the NIH (NIGMS) and she is a member of the American Society for Cell Biology.

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Latest work with IntechOpen by Paula Bubulya

A global research community of scientists is teasing out the biochemical mechanisms that regulate normal cellular physiology in a variety of organisms. Much of current research aims to understand the network of molecular reactions that regulate cellular homeostasis, and to learn what allows cells to sense stress and activate appropriate biochemical responses. Advanced molecular tools and state-of-the-art imaging techniques discussed in this book continue to provide novel insights into how environmental changes impact organisms, as well as to develop therapeutic interventions for correcting aberrant pathways in human disease.

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