Chapters authored
Reactive Oxygen Species and Antioxidant Interactions in Erythrocytes
There is a continuous generation of reactive oxygen species (ROS) in erythrocytes due to their microenvironment. Reactive oxygen species (ROS) and reactive nitrogen species are well known as both harmful and beneficial species. They help in activating the antioxidant enzymes. However, overproduction of ROS can cause fatal damage to cell structures, including lipids and membranes, proteins and cause oxidative stress. Erythrocytes have effective antioxidant defenses to maintain their structure and functions. They protect these cells from damage and maintain their activities. Studies have reported that antioxidant interventions in various situations have proved beneficial to erythrocytes. Therefore, they can be employed as in vitro models for antioxidant and free radical interactions and also are ideal cell models for translational studies.
Part of the book: The Erythrocyte