Chapters authored
Role of CRISPR Technology in Gene Editing of Emerging and Re-emerging Vector Borne Disease
Vector borne diseases are rampant across the world. Due to spread and establishment of vector species in different geographical areas, vector adaptation and resistance towards many insecticides the only option left is vector control for various vector borne diseases. Recent advancement in the field of genome editing have provided a variety of tools like, CRISPR, a novel genome editing techniques which can be applied for the control and prevention of many deadly diseases like dengue, chikungunya, filariasis, Japanese encephalitis and Zika. The present chapter is aimed to discuss the recent advancement in genome editing tools such as, their application, challenges, and limitations in vector control. Additionally, this chapter would potentially be advantageous to understand the hurdles, knowledge gaps in eliminating vector borne disease.
Part of the book: Mosquito Research
Visceral Leishmaniasis: An Overview and Integrated Analysis of the Current Status, Geographical Distribution and Its Transmission
Visceral leishmaniasis (VL) is a vector–borne disease transmitted by Phlebotomine sandflies, with up to 350 million people are at risk of developing infection globally. VL has a severe influence on the impoverished and undeveloped populations among several subcontinents. Early and accurate diagnosis and treatment remain crucial to the management of VL, which still depends on vector control. The present chapter objectives are to provide an overview of visceral leishmaniasis and to raise knowledge of the most recent progress in this condition’s management, treatment, and prevention. Additionally, this chapter could be helpful for comprehending the difficulties and knowledge gaps in eliminating this protozoan disease as well as for learning the planning lessons from the global management of diseases like malaria and tuberculosis.
Part of the book: Leishmania Parasites