Stephanie Welle

By Nitesh Kumar Jain, Anwar Khedr, Hisham Ahmed Mushtaq, Brian Bartlett, April Lanz, Greta Zoesch, Stephanie Welle, Sumeet Yadav, Thoyaja Koritala, Shikha Jain, Aysun Tekin, Ramesh Adhikari, Aishwarya Reddy Korsapati, Mool Chand, Vishwanath Pattan, Vikas Bansal, Ali Rabaan, Amos Lal, Hasnain Saifee Bawaadam, Aman Sethi, Lavanya Dondapati, Raghavendra Tirupathi, Mack Sheraton, Maureen Muigai, David Rokser, Chetna Dengri, Kovid Trivedi, Samir Chandra Gautam, Simon Zec, Ibtisam Rauf, Mantravadi Srinivasa Chandramouli, Rahul Kashyap and Syed Anjum Khan

Idiopathic pulmonary fibrosis (IPF) and Gastroesophageal reflux disease (GERD) commonly co-exist. Pathophysiological mechanisms causing IPF are still not well understood, and GERD has been implicated in both as a probable causative and disease-promoting entity. Although not conclusively proven, this relationship has been the subject of several studies, including therapeutic interventions aimed at treating GERD and its resultant effect on IPF and related outcomes. Our review aims to present the current concepts and understanding of these two disease processes, which are multifaceted. Their complex interaction includes epidemiology, pathophysiology, diagnosis, treatment, review of research studies conducted to date, and future directions for research.

Part of the book: Idiopathic Pulmonary Fibrosis