Mahmoud Lotfy

Dr. Mahmoud Lotfy began his career in a center of excellence in Egypt. It is the gastroenterology center, Mansoura University, Mansoura, Egypt. Here, Dr. Lotfy has learned the research methodologies and curricula in the Biotechnology Research Laboratories under supervision of Prof. Dr. Abdel-Fattah Attallah. Currently, Dr. Lotfy is an associate professor of molecular cell biology and immunology, molecular and cellular biology department, genetic engineering and biotechnology research institute (GEBRI) at Minufiya University, Sadat City, Minufiya, Egypt and department of applied medical sciences at Jouf University, Saudi Arabia. The research interests of Dr. Lotfy are concerned mainly with the molecular, cellular and immunologic backgrounds of the GIT diseases such as cancers, viral hepatitis and schistosomiasis. He completed and published many relevant studies. Dr. Lotfy is a reviewer in many international journals with high impact factor and his biography is included in who is who in medicine and healthcare.

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Latest work with IntechOpen by Mahmoud Lotfy

Gastric cancer is one of the most common tumors worldwide. It has a heterogeneous milieu, where the genetic background, tumor immunology, oxidative stress, and microbial infections are key players in the multiple stages of tumorigenesis. These diverse factors are linked to the prognosis of the gastric cancer and the survival of gastric cancer patients. This book is appropriate for scientists and students in the field of oncology, gastroenterology, molecular biology, immunology, cell biology, biology, biochemistry, and pathology. This authoritative text carefully explains the fundamentals, providing a general overview of the principles followed by more detailed explanations of these recent topics efficiently. The topics presented herein contain the most recent knowledge in gastric cancer concerning the oncogenic signaling, genetic instability, the epigenetic aspect, molecular features and their clinical implications, miRNAs, integrin and E-cadherin, carbohydrate-associated-transferases, free radicals, immune cell responses, mucins, Helicobacter-pylori, neoadjuvant and adjuvant therapy, prophylactic strategy for peritoneal recurrence, and hepatic metastasis.

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