Muhammad Tahir Aleem

By Muhammad Farhab, Muhammad Tahir Aleem, Shakseema Shaukat, Ayesha Qadry, Muhammad Zeeshan Ul Haq, Fateh Ullah, Muhammad Jawad and Amjad Islam Aqib

Staphylococcus aureus has vital importance in veterinary medicine. Within the ruminants, it is one of the major causes of mastitis, the problem that was and is, with no definite solution to date. Along with that, it also affects the health of animals, pets, and poultry in several ways as the tissue tropism for this organism in poultry is the bones and the joints. This review is focused on habitat, species differentiation, differential biochemical tests, pathogenesis, clinical infections, economic importance, public health significance, immune response, the regulation of virulence in the staphylococci, and cytokines response against S. aureus.

Part of the book: Insights Into Drug Resistance in Staphylococcus aureus

By Muhammad Abdullah Malik, Muhammad Sohail Sajid, Rao Zahid Abbas, Muhammad Tahir Aleem, Faisal Rasheed Anjum, Asad Khan, Muhammad Farhab, Mahvish Maqbool, Muhammad Zeeshan, Kashif Hussain, Namrah Rehman, Rana Hamid Ali Nisar, Hafiz Muhammad Rizwan and Urfa Bin Tahir

Anthelmintic, ectoparasiticides (insecticides, acaricides), and antiprotozoal chemotherapeutic drugs target parasites. Chenopodium oil like alkaloids, arsenic compounds, cupric sulfate, nicotine, and cupric silicate were used to destroy nematodes. Unfortunately, these chemicals were less effective and less safe for livestock. The four major groups of broad-spectrum antinematodal compounds are macrocyclic lactones such as milbemycins/ivermectin, benzimidazole/pro-benzimidazole, tetrahydro pyrimidines such as morantel, pyrantel tartrate, and imidazothiazoles such as tetramisole and levamisole. The various factors responsible for gastrointestinal (GI) parasitism make it difficult to develop effective control measures, to the best of our knowledge. Hence, an effective strategy for the control of parasitic diseases that do not solely rely on anthelmintic therapies needs to be developed at the regional level, based on the epidemiology of the disease. This book chapter aims to elaborate on the various other ways to control parasitic diseases due to Anthelmintic drug resistance.

Part of the book: Parasitic Helminths and Zoonoses

By Muhammad Tahir Aleem, Ruofeng Yan, Asad Khan, Rida Asrar, Amna Shakoor, Areej Asif, Zhaohai Wen, Zhengqing Yu, Muhammad Abdullah Malik, Tauseef-ur-Rehman, Rao Zahid Abbas, Muhammad Mohsin, Xiaokai Song, Lixin Xu and Xiangrui Li

Trichinellosis is a food-borne, zoonotic disease that causes infection by a nematode parasite belonging to the genus Trichinella. This is an important disease, and its causative agent is prevalent throughout the world (cosmopolitan). More clinical awareness of trichinellosis is required due to its many outbreaks, increase in the consumption of pork meat and its by-products. Trichinellosis is an epizootic in nature and its economic burden is associated with the prevention of this disease from the human food chain. This disease is transmitted from animals to humans through the consumption of raw or undercooked meat containing encapsulated muscle larvae of Trichinella spiralis. This paper demonstrates the direct effect of progesterone (P4) and mifepristone (RU486) on the progesterone receptors of T. spiralis. Also, studied the challenges in the preparation of DNA and recombinant protein vaccination to control trichinellosis. It is simply done this study at different life cycle developmental stages of T. spiralis. Vaccines development against T. spiralis infection is the new paradime shift from prevention of trichinellosis to fulfilling the food safety requirements.

Part of the book: Parasitic Helminths and Zoonoses