Maddalena Mognato is an assistant professor in Cell Biology with a Ph.D in Environmental Medicine. Her research activity is focused on cytotoxic and genotoxic effects induced by physical and chemical agents in human cells, both primary and tumoral. Several years ago she started studying the DNA-Damage Response (DDR) to ionizing radiation, focusing on microRNA/mRNA expression profiling and the repair of DNA double-strand breaks. She is currently engaged in research projects for the functional validation of miRNAs targeting genes of DNA double-strand break repair to sensitize radioresistant cancer cells, and for the definition of genetic profiling for individual radiation sensitivity. She have collaborated on projects funded by the European Union and studied the cytotoxic effects of silica nanoparticles and the biological properties of nanosystems formuled to improve the selectivity/efficacy of antitumoral therapy.