Chapters authored
Seabuckthorn Polyphenols: Characterization, Bioactivities and Associated Health Benefits
Sea Buckthorn (Hippophae rhamnoides) has a long history of use as food and medicine in Tibet and Northern Asia, where the plant has been associated with a wide range of health benefits. Sea buckthorn (SB) berry, seed and leaf have been reported to contain more than 190 bioactive compounds, including polyphenols (epicatechin, epigallocatechin, gallic acid, proanthocyanidins, chloregenic acid) and flavonoids (quercetin, isorhamnetin, kampferol glycosides, lutoelin, myricetin). SB represents a good source of phenolic compounds and flavonoids acting in synergy with PUFA such as omegas 3, 6, 7 and 9, vitamins (vitamin C), and organic acids. SB exerts antioxidant, anti-inflammatory, cytoprotective, anti-cancer, hepatoprotective properties, associated with improvement in various metabolic markers such as glycemic control and lipid profile. SB polyphenol fraction also demonstrated significant cardioprotective, antihypertensive and neuroprotective actions. SB acts as a natural stem cell mobilizer associated with significant regenerative properties. As a consequence, SB polyphenol consumption stimulates pancreatic regeneration in animal model of insulin-dependent diabetes. In conclusion, SB polyphenols exert a wide range of health benefits in metabolic health including obesity, diabetes and hypertension, as well as liver, kidney and brain health, positioning sea buckthorn berry extract as an interesting and valuable dietary supplement for natural complementary therapy and for antiaging.
Part of the book: Phenolic Compounds
Resveratrol, Multiple Bioactivities for a Wide Range of Health Benefits. New Innovative Extracts for Nutraceutical, Pharmaceutical, and Cosmetics Applications
Resveratrol (trans-resveratrol or 3,4′,5-trihydroxystilbene) is a polyphenol naturally present in grape skin and seeds. New innovative concentrated extracts produced by microorganisms or with innovative, ecological extraction techniques allow a new generation of high-quality ingredients for a diversity of product applications in nutraceuticals, cosmetics, and pharmaceuticals. Resveratrol exerts antioxidant and anti-inflammatory properties while promoting sirtuins 1 activities and mitochondrial functions. It also modulates multiple cellular signaling molecules, such as VEGF, caspases, cytokines NF-kB, vascular cell adhesion molecule, IGF-1, PPARs, and COX-2. Its clinical benefits have been demonstrated mainly in cognitive health, menopause, bone health, cardiovascular health, glucose metabolism, sport nutrition, and skin health. This chapter reviews the bioactivities of resveratrol, its clinical benefits, and detail its potential applications in several product categories in the growing field of health and nutrition product innovation. Resveratrol-based products may participate to provide new natural and complementary solutions for a global approach to health support and maintenance.
Part of the book: Resveratrol - Recent Advances, Application, and Therapeutic Potential [Working title]