Tsz Kwong Man

Dr Man received his PhD degree from the University of Texas Health Science Center at Houston, Texas, and subsequently completed his postdoctoral training at the Washington University at St. Louis, Missouri. He has more than 10 years of research experience in genomic, proteomic and bioinformatic characterizations of pediatric cancers and has published more than 30 original research articles and two book chapters. Dr Man is currently an associate professor of pediatrics at the Baylor College of Medicine in the fields of cancer proteomics and biomarker discovery. He is a member of several national organizations, including American Association for Cancer Research, and a steering committee member of the TARGET consortium for pediatric cancers in the National Cancer Institute.

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Biomedical research has entered a new era of characterizing a disease or a protein on a global scale. In the post-genomic era, Proteomics now plays an increasingly important role in dissecting molecular functions of proteins and discovering biomarkers in human diseases. Mass spectrometry, two-dimensional gel electrophoresis, and high-density antibody and protein arrays are some of the most commonly used methods in the Proteomics field. This book covers four important and diverse areas of current proteomic research: Proteomic Discovery of Disease Biomarkers, Proteomic Analysis of Protein Functions, Proteomic Approaches to Dissecting Disease Processes, and Organelles and Secretome Proteomics. We believe that clinicians, students and laboratory researchers who are interested in Proteomics and its applications in the biomedical field will find this book useful and enlightening. The use of proteomic methods in studying proteins in various human diseases has become an essential part of biomedical research.

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