Calciphytoliths (calcium oxalate calculi) have a great influence on human health and are a disease with a high likelihood of recurrence at a rate of more than 10% within a year. Plant flavonoids, saponins, and tannins are reported to be Litholytic by inhibiting calcium oxalate crystals or by their calcium channel blocking activity. Vitamins and minerals containing flora completely prevent deposition of oxalate by preventing pre-oxidation injury and restoring renal tissue antioxidants. So vitamin therapy also might protect against oxalate calculi deposition in the human kidneys. The present chapter discusses the impact of vitamins especially vitamin E, calcium, and low oxalate-containing plants for the management of various urinary or kidney disorders.
Part of the book: Vitamin E in Health and Disease
Microemulsions are lipid based drug delivery system consisting of oil, water, surfactant and often a co-surfactant. They are prepared in order to deliver the drug in an effective manner so as to obtain the desired therapeutic activity. Compared to other conventional therapy, they can deliver the drug in an efficient manner because of their characteristics like reduced particles size, lipid based drug delivery system, thermodynamic stability and economical scale up. Anti-cancer drugs can be easily incorporated into microemulsion so as to target the cancer cells. This helps in increasing the solubility, permeability and absorption of the poorly soluble and poorly permeable drugs, thereby helping in enhancing the bioavailability of the drug. In this chapter, we are also focusing on the herbal based formulations that will be helpful in effectively fighting against cancer cells with less or no side effects. A light has also been shed on the advantages and disadvantages of the microemulsions that will be helpful in considering them as an effective model to conquer cancer and promote the same in the upcoming years.
Part of the book: Surfactants and Detergents