Ayurveda is the oldest science of health care, explaining both the perspectives, i.e., prevention and cure of diseases. The fundamental principles of Ayurveda explore life’s philosophy, including the entire cosmos having five significant elements (Akash, Vayu, Agni, Jala, and Prithvi) establishing the Prakruti, i.e., a unique combination of physiological and psychological characteristics in a human being. In Ayurveda, Ahara (Diet), and Vihar (Exercise/Movements), fundamental pillars are thoroughly explained according to a specific Prakruti, which denotes personalized medicine in the present era. Diet is the essential factor that comprises the five significant elements with six rasas (Sweet, Sour, Saline, Pungent, Bitter, Astringent). Each Rasa has its specific nutritional properties helpful for the maintenance of health. Moreover, it also prevents diseases and plays a vital role in the restoration of health from disease conditions. The appropriate diet plan is essential in the pandemic situation because the digestive power (Agni) becomes hampered due to faulty lifestyle and unwholesome food habits that result in vitiation of three bio-humors (Vata, Pitta, Kapha) in the body. According to Ayurveda’s basic principles, weakened digestive power is the main culprit for forming various diseases. Therefore, it is highly imperative to select a suitable diet and behavioral regimes during pandemic situations.