Raymond Chuen-Chung Chang

University of Hong Kong

Dr. Chang is the Lab Chief for the Laboratory of Neurodegenerative Diseases in the School of Biomedical Sciences, member in The State Key Laboratory of Brain and Cognitive Sciences. He is also the Founder and Secretary of HKU Alzheimer’s Disease Research Network, organising International Alzheimer’s Disease Conference every year since 2000. Dr. Chang’s research interest is pathophysiological changes of Alzheimer’s disease (AD) and the risk factors leading to AD. He has published over 120 peer-reviewed papers and 14 book chapters in these areas. His h-index is 34 by Scopus, 43 by Google Scholar. He is a member in the Scientific Advisory Board of International AD/PD Symposium, Scientific Review Committee in Alzheimer Association, Senior Editor for Journal of Neuroimmune Pharmacology, and Editor-in-Chief for ‘American Journal of Alzheimer’s Disease and Other Dementias. He is the member of editorial board of more than 20 different journals, and grant reviewer for different grant agencies/Foundations.

3books edited

2chapters authored

Latest work with IntechOpen by Raymond Chuen-Chung Chang

Neurodegenerative Diseases - Processes, Prevention, Protection and Monitoring focuses on biological mechanisms, prevention, neuroprotection and even monitoring of disease progression. This book emphasizes the general biological processes of neurodegeneration in different neurodegenerative diseases. Although the primary etiology for different neurodegenerative diseases is different, there is a high level of similarity in the disease processes. The first three sections introduce how toxic proteins, intracellular calcium and oxidative stress affect different biological signaling pathways or molecular machineries to inform neurons to undergo degeneration. A section discusses how neighboring glial cells modulate or promote neurodegeneration. In the next section an evaluation is given of how hormonal and metabolic control modulate disease progression, which is followed by a section exploring some preventive methods using natural products and new pharmacological targets. We also explore how medical devices facilitate patient monitoring. This book is suitable for different readers: college students can use it as a textbook; researchers in academic institutions and pharmaceutical companies can take it as updated research information; health care professionals can take it as a reference book, even patients' families, relatives and friends can take it as a good basis to understand neurodegenerative diseases.

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