This chapter discusses control design of three different brake-by-wire actuators. The brakes studied include an Electro-Hydraulic brake with pressure modulation for wheel slip control, and two different Electro-Mechanical Brake configurations that directly use electric motors to control the movement of the caliper for wheel slip control. After modeling the actuators with the use of bond graphs, a cascaded control architecture is used to control these active systems. Individual controllers are designed using Youla robust control design method. Then, a feed-forward disturbance rejection is designed and added to the loops and its effectiveness is analyzed. Finally, a one-wheel model is used to compare these brake-by-wire systems in terms of stopping distance and actuator efforts.