Chapters authored
Neural Mechanisms of Feeding Behavior and Its Disorders
There are two forms of feeding behavior. The hypothalamus and the lower brainstem monitor the internal environment of the body and are involved in the control of feeding behavior to maintain energy balance and homeostasis (homeostasis-dependent feeding behavior). On the other hand, humans and animals, when placed in an environment similar to modern society (e.g., cafeterias), where organisms can easily ingest highly preferred foods, consume more than necessary (homeostasis-independent feeding behavior). The emotion/reward system, including the amygdala and nucleus accumbens, is involved in this type of feeding behavior. These two control systems interact in the lateral hypothalamic area (LHA), where feeding behavior is controlled by systems with higher activity. In modern society, there is abundant information on food, and high-calorie foods such as snacks are readily available. Thus, in modern society, the homeostasis-independent control system easily surpasses the homeostasis-dependent control system, which results in obesity. Various feeding and eating disorders might be ascribed to dysregulations in the two control systems. In the future, more effective treatments for feeding and eating disorders can be developed by elucidating the mechanisms of these two control systems.
Part of the book: New Insights Into Metabolic Syndrome