Chapters authored
Medicinal Plants Having Antifungal Properties
In the past few decades, a worldwide increase in the incidence of fungal infections has been observed as well as rise in the resistance of some species of fungi to different fungicidal used in medicinal practice. Besides, fungi are the one of the most neglected pathogens as demonstrated by the fact that the amphotericin B and other sold treatments are still used as gold standard as antifungal therapy. The majority of used antifungal treatments have various drawbacks in terms of toxicity, efficacy as well as cost and their frequent use has also led to the emergence of resistant strains. Hence, there is a great demand for developing an antifungal belonging to a wide range of structural classes, selectively acting on new targets with least side effects. Natural products, either as pure phytocompounds or as standardized plant extracts, provide unlimited opportunities for new drug lads because of their having normally matchless chemical diversity. Present chapter focused on the work done in the field of antifungal activities of various plant components and novel approaches which will be the future prospective for the new drug discoveries and providing better antifungal therapy.
Part of the book: Medicinal Plants
Role of Nanobiotechnology in Drug Discovery, Development and Molecular Diagnostic
Nano-biotechnology has already tested its magnitude in a number of sections of existence science and biotechnology field. It is no longer hyperbole to say that in future, nano-scale method would in reality take the associated science area to the subsequent level. Since, there are technical hurdles present; despite the fact that scientists are giving their great to overcome such problems. Applications of nano-biotechnology have already been discussed in this chapter. Future potential are really associated with innovative amendment of such applications. Despite of some impedance, this technology presents giant hope in the future. It performs most important position in distinct sorts of biomedical application such as shipping of drug, gene therapy, biosensors, biomarkers and molecular imaging. It additionally leads to innovations in this field. The fundamental lookup goal of this discipline would be the innovation of early analysis approach and cure with target-specific remedy therapy. Although there would possibly be some safety worries with admire to the in vivo use of nanoparticles, research are in region to decide the nature and extent of adverse events.
Part of the book: Applications of Nanobiotechnology
Risk-Benefit Events Associated with the Use of Aspirin for Primary Prevention of Cardiovascular Disorders
Aspirin had been introduced as a nonsteroidal anti-inflammatory molecule. As further research on aspirin started, other therapeutic effects have been revealed. Now, this molecule has become the polychrest in medical science. Aspirin has served as a drug of choice for the primary prevention of cardiovascular disease (CVD) for the last few decades. However, recent trials have raised questions on the use of aspirin for CVD prevention due to some life-threatening adverse drug events. In spite of that, outcomes of trials will surely assist to frame a guideline for anoxic administration regimen of aspirin in order to prevent CVD.
Part of the book: Drug Repurposing