Dhruv Kumar

University of Kansas Medical CenterUnited States of America

Dr. Dhruv Kumar completed his PhD in Cellular, Molecular and Industrial Biology from the University of Bologna (UNIBO), Italy under one of the prestigious fellowships of Ministry of Human Resource and Development (MHRD), Indo-Italian Government fellowship in 2012. After completion of his PhD, he received five years of Postdoctoral training from the School of Medicine, University of Kansas MedicalCenter, Kansas City, USA. During his Postdoctoral training, he worked on several cancers , including Prostate, Pancreatic, Brain, Breast and Head and Neck Cancer. His research work was focused on understanding the molecular mechanism (s) of the regulation of Autophagy and Apoptosis in Cancer Stem Cells (Prostate, Pancreatic, Brain and Breast). Specifically, he studied the molecular mechanism (s) of Rottlerin-induced Autophagy in Cancer Stem Cells (CSCs) via PI3K/Akt/mTOR signaling pathways. He has also explored the molecular cross-talk between the tumor microenvironment (Cancer Associated Fibroblast (CAF)) and Head and Neck Squamous Cell Carcinoma (HNSCC) via HGF/c-MET and bFGF/FGFR signaling pathways, intra-tumor mutational heterogeneity, developed an in vitro model for Radiation Induced Fibrosis (RIF), molecular mechanism (s) of combination of naturally derived chemo-preventive agents (Curcumin in combination with other anticancer compounds) in Cancer cells, characterization of exosomes released from cancer stem cells (CSCs), role of phytochemicals in epigenetic modulation in cancer and cancer stem cells and metabolic alteration in cancer and cancer stem cells. Apart from his, research, he is actively involved in teaching courses at UG, PG and PhD level related to Cancer Biology, Stem Cell Biology, Molecular Medicine and Bioinformatics.

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