Rapid progress of technologies does not only exclusively belong to developed countries nowadays but also spread out to developing countries including Indonesia. There are many Indonesian universities and emerging translational medicine centers that had declared themselves as research centers focusing on to bring science from bench to bedside. Since the outbreak of 2007 Avian Influenza, Indonesia had been starting to accumulate more knowledge and experiences related to biosafety and biosecurity. While Indonesian researchers were focusing on biorisk management of high pathogenic bioagents, students were also being exposed gradually to more sophisticated biological hazards through the utilization of synthetic biology and genetic modifications on their own researches. Nurturing the responsible future generation of scientist whom aware of the ethical, biosafety, biosecurity concerns cannot become more important, considering the possibility of dual use research results, which could bring either prosperity or chaos to the universe.