History of Classification of Gastritis.
\\n\\n
More than half of the publishers listed alongside IntechOpen (18 out of 30) are Social Science and Humanities publishers. IntechOpen is an exception to this as a leader in not only Open Access content but Open Access content across all scientific disciplines, including Physical Sciences, Engineering and Technology, Health Sciences, Life Science, and Social Sciences and Humanities.
\\n\\nOur breakdown of titles published demonstrates this with 47% PET, 31% HS, 18% LS, and 4% SSH books published.
\\n\\n“Even though ItechOpen has shown the potential of sci-tech books using an OA approach,” other publishers “have shown little interest in OA books.”
\\n\\nAdditionally, each book published by IntechOpen contains original content and research findings.
\\n\\nWe are honored to be among such prestigious publishers and we hope to continue to spearhead that growth in our quest to promote Open Access as a true pioneer in OA book publishing.
\\n\\n\\n\\n
\\n"}]',published:!0,mainMedia:null},components:[{type:"htmlEditorComponent",content:'
Simba Information has released its Open Access Book Publishing 2020 - 2024 report and has again identified IntechOpen as the world’s largest Open Access book publisher by title count.
\n\nSimba Information is a leading provider for market intelligence and forecasts in the media and publishing industry. The report, published every year, provides an overview and financial outlook for the global professional e-book publishing market.
\n\nIntechOpen, De Gruyter, and Frontiers are the largest OA book publishers by title count, with IntechOpen coming in at first place with 5,101 OA books published, a good 1,782 titles ahead of the nearest competitor.
\n\nSince the first Open Access Book Publishing report published in 2016, IntechOpen has held the top stop each year.
\n\n\n\nMore than half of the publishers listed alongside IntechOpen (18 out of 30) are Social Science and Humanities publishers. IntechOpen is an exception to this as a leader in not only Open Access content but Open Access content across all scientific disciplines, including Physical Sciences, Engineering and Technology, Health Sciences, Life Science, and Social Sciences and Humanities.
\n\nOur breakdown of titles published demonstrates this with 47% PET, 31% HS, 18% LS, and 4% SSH books published.
\n\n“Even though ItechOpen has shown the potential of sci-tech books using an OA approach,” other publishers “have shown little interest in OA books.”
\n\nAdditionally, each book published by IntechOpen contains original content and research findings.
\n\nWe are honored to be among such prestigious publishers and we hope to continue to spearhead that growth in our quest to promote Open Access as a true pioneer in OA book publishing.
\n\n\n\n
\n'}],latestNews:[{slug:"intechopen-maintains-position-as-the-world-s-largest-oa-book-publisher-20201218",title:"IntechOpen Maintains Position as the World’s Largest OA Book Publisher"},{slug:"all-intechopen-books-available-on-perlego-20201215",title:"All IntechOpen Books Available on Perlego"},{slug:"oiv-awards-recognizes-intechopen-s-editors-20201127",title:"OIV Awards Recognizes IntechOpen's Editors"},{slug:"intechopen-joins-crossref-s-initiative-for-open-abstracts-i4oa-to-boost-the-discovery-of-research-20201005",title:"IntechOpen joins Crossref's Initiative for Open Abstracts (I4OA) to Boost the Discovery of Research"},{slug:"intechopen-hits-milestone-5-000-open-access-books-published-20200908",title:"IntechOpen hits milestone: 5,000 Open Access books published!"},{slug:"intechopen-books-hosted-on-the-mathworks-book-program-20200819",title:"IntechOpen Books Hosted on the MathWorks Book Program"},{slug:"intechopen-s-chapter-awarded-the-guenther-von-pannewitz-preis-2020-20200715",title:"IntechOpen's Chapter Awarded the Günther-von-Pannewitz-Preis 2020"},{slug:"suf-and-intechopen-announce-collaboration-20200331",title:"SUF and IntechOpen Announce Collaboration"}]},book:{item:{type:"book",id:"506",leadTitle:null,fullTitle:"Advanced Biomedical Engineering",title:"Advanced Biomedical Engineering",subtitle:null,reviewType:"peer-reviewed",abstract:"This book presents a collection of recent and extended academic works in selected topics of biomedical signal processing, bio-imaging and biomedical ethics and legislation. This wide range of topics provide a valuable update to researchers in the multidisciplinary area of biomedical engineering and an interesting introduction for engineers new to the area. The techniques covered include modelling, experimentation and discussion with the application areas ranging from acoustics to oncology, health education and cardiovascular disease.",isbn:null,printIsbn:"978-953-307-555-6",pdfIsbn:"978-953-51-4453-3",doi:"10.5772/1017",price:119,priceEur:129,priceUsd:155,slug:"advanced-biomedical-engineering",numberOfPages:292,isOpenForSubmission:!1,isInWos:1,hash:"8ae90cb19bbf5c0a612d7cf490464f8d",bookSignature:"Gaetano D. Gargiulo and Alistair McEwan",publishedDate:"August 23rd 2011",coverURL:"https://cdn.intechopen.com/books/images_new/506.jpg",numberOfDownloads:50307,numberOfWosCitations:53,numberOfCrossrefCitations:28,numberOfDimensionsCitations:52,hasAltmetrics:0,numberOfTotalCitations:133,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"October 25th 2010",dateEndSecondStepPublish:"November 22nd 2010",dateEndThirdStepPublish:"March 29th 2011",dateEndFourthStepPublish:"April 28th 2011",dateEndFifthStepPublish:"June 27th 2011",currentStepOfPublishingProcess:5,indexedIn:"1,2,3,4,5,6,7,8",editedByType:"Edited by",kuFlag:!1,editors:[{id:"24082",title:"Dr.",name:"Gaetano",middleName:"D.",surname:"Gargiulo",slug:"gaetano-gargiulo",fullName:"Gaetano Gargiulo",profilePictureURL:"https://mts.intechopen.com/storage/users/24082/images/1694_n.jpg",biography:"Gaetano D. Gargiulo (IEEE M007) is senior Biomedical Engineer at HEARD Systems, Australia, and research affiliate at The University of Sydney, Australia and “Federico II” University of Naples, Italy. He received his DPhil from “Alma Mater” University of Bologna, Italy in 2010. He is currently working on bio-instrumentations applied research at HEARD Systems. His research interests include medical instrumentation, telemedicine, human-computer interfaces and bio-inspired systems. He has authored or co-authored more than 30 papers in these research areas and is an inventor on 3 patents.",institutionString:null,position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"0",totalChapterViews:"0",totalEditedBooks:"2",institution:null}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,coeditorOne:{id:"24083",title:"Dr.",name:"Alistair",middleName:null,surname:"McEwan",slug:"alistair-mcewan",fullName:"Alistair McEwan",profilePictureURL:"https://mts.intechopen.com/storage/users/24083/images/1696_n.jpg",biography:"Alistair McEwan (IEEE M9-SM9) is Lecturer of Computer Engineering at The University of Sydney, Australia. He received his DPhil from Oxford University, UK in 2005. He did postdoctoral research at University College London, UK, and then at Philips Research Labs in Germany as a Marie Curie Research Fellow. His research interests include medical instrumentation, integrated circuit design, and bio-inspired systems. He has authored or co-authored more than 50 papers in these research areas and is an inventor on 4 patents.",institutionString:null,position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"3",totalChapterViews:"0",totalEditedBooks:"0",institution:null},coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"685",title:"Bioinformatics",slug:"engineering-biomedical-engineering-bioinformatics"}],chapters:[{id:"18366",title:"Spatial Unmasking of Speech Based on Near-Field Distance Cues",doi:"10.5772/25282",slug:"spatial-unmasking-of-speech-based-on-near-field-distance-cues",totalDownloads:1959,totalCrossrefCites:0,totalDimensionsCites:0,signatures:"Craig Jin, Virginia Best, Gaven Lin and Simon Carlile",downloadPdfUrl:"/chapter/pdf-download/18366",previewPdfUrl:"/chapter/pdf-preview/18366",authors:[{id:"24072",title:"Prof.",name:"Craig",surname:"Jin",slug:"craig-jin",fullName:"Craig Jin"},{id:"126156",title:"Mr.",name:"Gaven",surname:"Lin",slug:"gaven-lin",fullName:"Gaven Lin"},{id:"126157",title:"Dr.",name:"Virginia",surname:"Best",slug:"virginia-best",fullName:"Virginia Best"},{id:"126158",title:"Dr.",name:"Simon",surname:"Carlile",slug:"simon-carlile",fullName:"Simon Carlile"}],corrections:null},{id:"18367",title:"Pulse Wave Analysis",doi:"10.5772/22600",slug:"pulse-wave-analysis",totalDownloads:8359,totalCrossrefCites:8,totalDimensionsCites:10,signatures:"Zhaopeng Fan, Gong Zhang and Simon Liao",downloadPdfUrl:"/chapter/pdf-download/18367",previewPdfUrl:"/chapter/pdf-preview/18367",authors:[{id:"24603",title:"Dr.",name:"Gong",surname:"Zhang",slug:"gong-zhang",fullName:"Gong Zhang"},{id:"103967",title:"Dr.",name:"Zhaopeng",surname:"Fan",slug:"zhaopeng-fan",fullName:"Zhaopeng Fan"},{id:"126697",title:"Dr.",name:"Simon",surname:"Liao",slug:"simon-liao",fullName:"Simon Liao"}],corrections:null},{id:"18368",title:"Multivariate Models and Algorithms for Learning Correlation Structures from Replicated Molecular Profiling Data",doi:"10.5772/19484",slug:"multivariate-models-and-algorithms-for-learning-correlation-structures-from-replicated-molecular-pro",totalDownloads:1669,totalCrossrefCites:0,totalDimensionsCites:0,signatures:"Lipi R. Acharya and Dongxiao Zhu",downloadPdfUrl:"/chapter/pdf-download/18368",previewPdfUrl:"/chapter/pdf-preview/18368",authors:[{id:"20696",title:"Dr.",name:"Dongxiao",surname:"Zhu",slug:"dongxiao-zhu",fullName:"Dongxiao Zhu"},{id:"35108",title:"Dr.",name:"Lipi R.",surname:"Acharya",slug:"lipi-r.-acharya",fullName:"Lipi R. Acharya"}],corrections:null},{id:"18369",title:"Biomedical Time Series Processing and Analysis Methods: The Case of Empirical Mode Decomposition",doi:"10.5772/20906",slug:"biomedical-time-series-processing-and-analysis-methods-the-case-of-empirical-mode-decomposition",totalDownloads:3261,totalCrossrefCites:0,totalDimensionsCites:0,signatures:"Alexandros Karagiannis, Philip Constantinou and Demosthenes Vouyioukas",downloadPdfUrl:"/chapter/pdf-download/18369",previewPdfUrl:"/chapter/pdf-preview/18369",authors:[{id:"21863",title:"Prof.",name:"Philip",surname:"Constantinou",slug:"philip-constantinou",fullName:"Philip Constantinou"},{id:"40966",title:"MSc",name:"Alexandros",surname:"Karagiannis",slug:"alexandros-karagiannis",fullName:"Alexandros Karagiannis"},{id:"43110",title:"Prof.",name:"Demosthenes",surname:"Vouyioukas",slug:"demosthenes-vouyioukas",fullName:"Demosthenes Vouyioukas"}],corrections:null},{id:"18370",title:"Global Internet Protocol for Ubiquitous Healthcare Monitoring Applications",doi:"10.5772/21018",slug:"global-internet-protocol-for-ubiquitous-healthcare-monitoring-applications",totalDownloads:2145,totalCrossrefCites:1,totalDimensionsCites:1,signatures:"Dhananjay Singh",downloadPdfUrl:"/chapter/pdf-download/18370",previewPdfUrl:"/chapter/pdf-preview/18370",authors:[{id:"41461",title:"Dr.",name:"Dhananjay",surname:"Singh",slug:"dhananjay-singh",fullName:"Dhananjay Singh"}],corrections:null},{id:"18371",title:"Recent Developments in Cell-Based Microscale Technologies and Their Potential Application in Personalised Medicine",doi:"10.5772/23013",slug:"recent-developments-in-cell-based-microscale-technologies-and-their-potential-application-in-persona",totalDownloads:2352,totalCrossrefCites:1,totalDimensionsCites:1,signatures:"Gregor Kijanka, Robert Burger, Ivan K. Dimov, Rima Padovani, Karen Lawler, Richard O'Kennedy and Jens Ducrée",downloadPdfUrl:"/chapter/pdf-download/18371",previewPdfUrl:"/chapter/pdf-preview/18371",authors:[{id:"50173",title:"Dr.",name:"Gregor",surname:"Kijanka",slug:"gregor-kijanka",fullName:"Gregor Kijanka"},{id:"50196",title:"Mr.",name:"Robert",surname:"Burger",slug:"robert-burger",fullName:"Robert Burger"},{id:"50197",title:"Dr.",name:"Ivan K.",surname:"Dimov",slug:"ivan-k.-dimov",fullName:"Ivan K. Dimov"},{id:"50198",title:"Prof.",name:"Richard",surname:"O'Kennedy",slug:"richard-o'kennedy",fullName:"Richard O'Kennedy"},{id:"50199",title:"Prof.",name:"Jens",surname:"Ducrée",slug:"jens-ducree",fullName:"Jens Ducrée"},{id:"50229",title:"Ms",name:"Rima",surname:"Padovani",slug:"rima-padovani",fullName:"Rima Padovani"},{id:"51000",title:"Dr.",name:"Karen",surname:"Lawler",slug:"karen-lawler",fullName:"Karen Lawler"},{id:"127051",title:"Prof.",name:"Ivan K.",surname:"Dimov",slug:"ivan-k.-dimov",fullName:"Ivan K. Dimov"},{id:"127052",title:"Prof.",name:"Karen",surname:"Lawler",slug:"karen-lawler",fullName:"Karen Lawler"},{id:"127053",title:"Prof.",name:"Rima",surname:"Padovani",slug:"rima-padovani",fullName:"Rima Padovani"}],corrections:null},{id:"18386",title:"Fine Biomedical Imaging Using X-Ray Phase-Sensitive Technique",doi:"10.5772/20456",slug:"fine-biomedical-imaging-using-x-ray-phase-sensitive-technique",totalDownloads:2385,totalCrossrefCites:11,totalDimensionsCites:15,signatures:"Akio Yoneyama, Shigehito Yamada and Tohoru Takeda",downloadPdfUrl:"/chapter/pdf-download/18386",previewPdfUrl:"/chapter/pdf-preview/18386",authors:[{id:"39027",title:"Dr.",name:"Akio",surname:"Yoneyama",slug:"akio-yoneyama",fullName:"Akio Yoneyama"},{id:"49485",title:"Dr.",name:"Tohoru",surname:"Takeda",slug:"tohoru-takeda",fullName:"Tohoru Takeda"},{id:"49486",title:"Prof.",name:"Shigehito",surname:"Yamada",slug:"shigehito-yamada",fullName:"Shigehito Yamada"}],corrections:null},{id:"18387",title:"Diffusion of Methylene Blue in Phantoms of Agar Using Optical Absorption Techniques",doi:"10.5772/20589",slug:"diffusion-of-methylene-blue-in-phantoms-of-agar-using-optical-absorption-techniques",totalDownloads:4181,totalCrossrefCites:0,totalDimensionsCites:0,signatures:"Lidia Vilca-Quispe, Alejandro Castilla-Loeza, Juan José Alvarado-Gil and Patricia Quintana-Owen",downloadPdfUrl:"/chapter/pdf-download/18387",previewPdfUrl:"/chapter/pdf-preview/18387",authors:[{id:"39613",title:"Prof.",name:"Juan Jose",surname:"Alvarado-Gil",slug:"juan-jose-alvarado-gil",fullName:"Juan Jose Alvarado-Gil"},{id:"41221",title:"Dr.",name:"Patricia",surname:"Quintana-Owen",slug:"patricia-quintana-owen",fullName:"Patricia Quintana-Owen"},{id:"49633",title:"MSc",name:"Lidia",surname:"Vilca-Quispe",slug:"lidia-vilca-quispe",fullName:"Lidia Vilca-Quispe"},{id:"49634",title:"MSc.",name:"Alejandro",surname:"Castilla-Loeza",slug:"alejandro-castilla-loeza",fullName:"Alejandro Castilla-Loeza"}],corrections:null},{id:"18388",title:"Semiconductor II-VI Quantum Dots with Interface States and Their Biomedical Applications",doi:"10.5772/20628",slug:"semiconductor-ii-vi-quantum-dots-with-interface-states-and-their-biomedical-applications",totalDownloads:4934,totalCrossrefCites:7,totalDimensionsCites:16,signatures:"Tetyana Torchynska and Yuri Vorobiev",downloadPdfUrl:"/chapter/pdf-download/18388",previewPdfUrl:"/chapter/pdf-preview/18388",authors:[{id:"39822",title:"Prof.",name:"Yuri",surname:"Vorobiev",slug:"yuri-vorobiev",fullName:"Yuri Vorobiev"},{id:"39831",title:"Prof.",name:"Tetyana",surname:"Torchynska",slug:"tetyana-torchynska",fullName:"Tetyana Torchynska"}],corrections:null},{id:"18389",title:"Image Processing Methods for Automatic Cell Counting In Vivo or In Situ Using 3D Confocal Microscopy",doi:"10.5772/23147",slug:"image-processing-methods-for-automatic-cell-counting-in-vivo-or-in-situ-using-3d-confocal-microscopy",totalDownloads:3886,totalCrossrefCites:0,totalDimensionsCites:6,signatures:"Manuel G. Forero and Alicia Hidalgo",downloadPdfUrl:"/chapter/pdf-download/18389",previewPdfUrl:"/chapter/pdf-preview/18389",authors:[{id:"50812",title:"Dr.",name:"Alicia",surname:"Hidalgo",slug:"alicia-hidalgo",fullName:"Alicia Hidalgo"},{id:"92341",title:"Dr.",name:"Manuel G.",surname:"Forero",slug:"manuel-g.-forero",fullName:"Manuel G. Forero"}],corrections:null},{id:"18390",title:"Cross Cultural Principles for Bioethics",doi:"10.5772/18420",slug:"cross-cultural-principles-for-bioethics",totalDownloads:5758,totalCrossrefCites:0,totalDimensionsCites:1,signatures:"Mette Ebbesen",downloadPdfUrl:"/chapter/pdf-download/18390",previewPdfUrl:"/chapter/pdf-preview/18390",authors:[{id:"31457",title:"Dr.",name:"Mette",surname:"Ebbesen",slug:"mette-ebbesen",fullName:"Mette Ebbesen"}],corrections:null},{id:"18391",title:"Multi-Faceted Search and Navigation of Biological Databases",doi:"10.5772/18456",slug:"multi-faceted-search-and-navigation-of-biological-databases",totalDownloads:2583,totalCrossrefCites:0,totalDimensionsCites:0,signatures:"Mahoui M., Oklak M. and Perumal N.",downloadPdfUrl:"/chapter/pdf-download/18391",previewPdfUrl:"/chapter/pdf-preview/18391",authors:[{id:"31557",title:"Dr.",name:"Malika",surname:"Mahoui",slug:"malika-mahoui",fullName:"Malika Mahoui"},{id:"51031",title:"Mr.",name:"Narayanan",surname:"Perumal",slug:"narayanan-perumal",fullName:"Narayanan Perumal"},{id:"51035",title:"Mr",name:"Mark",surname:"Oklak",slug:"mark-oklak",fullName:"Mark Oklak"}],corrections:null},{id:"18392",title:"Integrating the Electronic Health Record into Education: Models, Issues and Considerations for Training Biomedical Engineers",doi:"10.5772/19583",slug:"integrating-the-electronic-health-record-into-education-models-issues-and-considerations-for-trainin",totalDownloads:3333,totalCrossrefCites:0,totalDimensionsCites:0,signatures:"Elizabeth Borycki, Andre Kushniruk, Mu-Hsing Kuo and Brian Armstrong",downloadPdfUrl:"/chapter/pdf-download/18392",previewPdfUrl:"/chapter/pdf-preview/18392",authors:[{id:"919",title:"Dr.",name:"Andre",surname:"Kushniruk",slug:"andre-kushniruk",fullName:"Andre Kushniruk"},{id:"35432",title:"Dr.",name:"Elizabeth",surname:"Borycki",slug:"elizabeth-borycki",fullName:"Elizabeth Borycki"},{id:"51206",title:"Dr.",name:"Mu-Hsing",surname:"Kuo",slug:"mu-hsing-kuo",fullName:"Mu-Hsing Kuo"},{id:"127057",title:"Prof.",name:"Brian",surname:"Armstrong",slug:"brian-armstrong",fullName:"Brian Armstrong"}],corrections:null},{id:"18393",title:"Appropriateness and Adequacy of the Keywords Listed in Papers Published in Eating Disorders Journals Indexed Using the MEDLINE Database",doi:"10.5772/18968",slug:"appropriateness-and-adequacy-of-the-keywords-listed-in-papers-published-in-eating-disorders-journals",totalDownloads:1525,totalCrossrefCites:0,totalDimensionsCites:2,signatures:"Javier Sanz-Valero, Rocio Guardiola-Wanden-Berghe and Carmina Wanden-Berghe",downloadPdfUrl:"/chapter/pdf-download/18393",previewPdfUrl:"/chapter/pdf-preview/18393",authors:[{id:"33171",title:"Dr.",name:"Javier",surname:"Sanz-Valero",slug:"javier-sanz-valero",fullName:"Javier Sanz-Valero"},{id:"47335",title:"Ms.",name:"Rocio",surname:"Guardiola-Wanden-Berghe",slug:"rocio-guardiola-wanden-berghe",fullName:"Rocio Guardiola-Wanden-Berghe"},{id:"47336",title:"Prof.",name:"Carmina",surname:"Wanden-Berghe",slug:"carmina-wanden-berghe",fullName:"Carmina Wanden-Berghe"},{id:"127058",title:"Prof.",name:"Javier",surname:"Sanz-Valero",slug:"javier-sanz-valero",fullName:"Javier Sanz-Valero"},{id:"127059",title:"Prof.",name:"Rocio",surname:"Guardiola-Wanden-Berghe",slug:"rocio-guardiola-wanden-berghe",fullName:"Rocio Guardiola-Wanden-Berghe"}],corrections:null},{id:"18394",title:"Legislation, Standardization and Technological Solutions for Enhancing e-Accessibility in e-Health",doi:"10.5772/19721",slug:"legislation-standardization-and-technological-solutions-for-enhancing-e-accessibility-in-e-health",totalDownloads:1986,totalCrossrefCites:0,totalDimensionsCites:0,signatures:"Pilar Del Valle García, Ignacio Martínez Ruiz, Javier Escayola Calvo, Jesús Daniel Trigo Vilaseca and José García Moros",downloadPdfUrl:"/chapter/pdf-download/18394",previewPdfUrl:"/chapter/pdf-preview/18394",authors:[{id:"35964",title:"Dr.",name:"Ignacio",surname:"Martínez Ruiz",slug:"ignacio-martinez-ruiz",fullName:"Ignacio Martínez Ruiz"},{id:"49986",title:"MSc",name:"Pilar",surname:"Del Valle Garcia",slug:"pilar-del-valle-garcia",fullName:"Pilar Del Valle Garcia"},{id:"49987",title:"MSc.",name:"Jesús Daniel",surname:"Trigo Vilaseca",slug:"jesus-daniel-trigo-vilaseca",fullName:"Jesús Daniel Trigo Vilaseca"},{id:"49988",title:"Dr.",name:"José",surname:"García Moros",slug:"jose-garcia-moros",fullName:"José García Moros"},{id:"86104",title:"MSc.",name:"Javier",surname:"Escayola Calvo",slug:"javier-escayola-calvo",fullName:"Javier Escayola Calvo"}],corrections:null}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},relatedBooks:[{type:"book",id:"238",title:"Applied Biomedical Engineering",subtitle:null,isOpenForSubmission:!1,hash:"b85b6fd9a3e8bedfbc1592745a0dfba3",slug:"applied-biomedical-engineering",bookSignature:"Gaetano D. Gargiulo and Alistair McEwan",coverURL:"https://cdn.intechopen.com/books/images_new/238.jpg",editedByType:"Edited by",editors:[{id:"24082",title:"Dr.",name:"Gaetano",surname:"Gargiulo",slug:"gaetano-gargiulo",fullName:"Gaetano Gargiulo"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3703",title:"New Developments in Biomedical Engineering",subtitle:null,isOpenForSubmission:!1,hash:null,slug:"new-developments-in-biomedical-engineering",bookSignature:"Domenico Campolo",coverURL:"https://cdn.intechopen.com/books/images_new/3703.jpg",editedByType:"Edited by",editors:[{id:"1909",title:"Dr.",name:"Domenico",surname:"Campolo",slug:"domenico-campolo",fullName:"Domenico Campolo"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"3222",title:"State of the Art in Biosensors",subtitle:"General Aspects",isOpenForSubmission:!1,hash:"0057daafc7f0654587e99f5fc3f03a34",slug:"state-of-the-art-in-biosensors-general-aspects",bookSignature:"Toonika Rinken",coverURL:"https://cdn.intechopen.com/books/images_new/3222.jpg",editedByType:"Edited by",editors:[{id:"24687",title:"Dr.",name:"Toonika",surname:"Rinken",slug:"toonika-rinken",fullName:"Toonika Rinken"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"2715",title:"Independent Component Analysis for Audio and Biosignal Applications",subtitle:null,isOpenForSubmission:!1,hash:"3915fb2a427c73e9aeee010bb1857ae5",slug:"independent-component-analysis-for-audio-and-biosignal-applications",bookSignature:"Ganesh R Naik",coverURL:"https://cdn.intechopen.com/books/images_new/2715.jpg",editedByType:"Edited by",editors:[{id:"2276",title:"Dr.",name:"Ganesh R.",surname:"Naik",slug:"ganesh-r.-naik",fullName:"Ganesh R. Naik"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6573",title:"Bioinformatics in the Era of Post Genomics and Big Data",subtitle:null,isOpenForSubmission:!1,hash:"ebdf5cb36c49d7d0eaa38059c4434ee4",slug:"bioinformatics-in-the-era-of-post-genomics-and-big-data",bookSignature:"Ibrokhim Y. Abdurakhmonov",coverURL:"https://cdn.intechopen.com/books/images_new/6573.jpg",editedByType:"Edited by",editors:[{id:"213344",title:"Dr.",name:"Ibrokhim Y.",surname:"Abdurakhmonov",slug:"ibrokhim-y.-abdurakhmonov",fullName:"Ibrokhim Y. Abdurakhmonov"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7639",title:"Bioinformatics Tools for Detection and Clinical Interpretation of Genomic Variations",subtitle:null,isOpenForSubmission:!1,hash:"94f9f01b510ca80812f0eee467f9428b",slug:"bioinformatics-tools-for-detection-and-clinical-interpretation-of-genomic-variations",bookSignature:"Ali Samadikuchaksaraei and Morteza Seifi",coverURL:"https://cdn.intechopen.com/books/images_new/7639.jpg",editedByType:"Edited by",editors:[{id:"187501",title:"Prof.",name:"Ali",surname:"Samadikuchaksaraei",slug:"ali-samadikuchaksaraei",fullName:"Ali Samadikuchaksaraei"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10107",title:"Artificial Intelligence in Oncology Drug Discovery and Development",subtitle:null,isOpenForSubmission:!1,hash:"043c178c3668865ab7d35dcb2ceea794",slug:"artificial-intelligence-in-oncology-drug-discovery-and-development",bookSignature:"John W. Cassidy and Belle Taylor",coverURL:"https://cdn.intechopen.com/books/images_new/10107.jpg",editedByType:"Edited by",editors:[{id:"244455",title:"Dr.",name:"John",surname:"Cassidy",slug:"john-cassidy",fullName:"John Cassidy"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9236",title:"Cheminformatics and its Applications",subtitle:null,isOpenForSubmission:!1,hash:"3fed97d1719b8a321190c86985494a34",slug:"cheminformatics-and-its-applications",bookSignature:"Amalia Stefaniu, Azhar Rasul and Ghulam Hussain",coverURL:"https://cdn.intechopen.com/books/images_new/9236.jpg",editedByType:"Edited by",editors:[{id:"213696",title:"Dr.",name:"Amalia",surname:"Stefaniu",slug:"amalia-stefaniu",fullName:"Amalia Stefaniu"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6835",title:"Computer Methods and Programs in Biomedical Signal and Image Processing",subtitle:null,isOpenForSubmission:!1,hash:"19f08ef15d97900c94dc8fb04f9afb5f",slug:"computer-methods-and-programs-in-biomedical-signal-and-image-processing",bookSignature:"Lulu Wang",coverURL:"https://cdn.intechopen.com/books/images_new/6835.jpg",editedByType:"Edited by",editors:[{id:"257388",title:"Distinguished Prof.",name:"Lulu",surname:"Wang",slug:"lulu-wang",fullName:"Lulu Wang"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7723",title:"Artificial Intelligence",subtitle:"Applications in Medicine and Biology",isOpenForSubmission:!1,hash:"a3852659e727f95c98c740ed98146011",slug:"artificial-intelligence-applications-in-medicine-and-biology",bookSignature:"Marco Antonio Aceves-Fernandez",coverURL:"https://cdn.intechopen.com/books/images_new/7723.jpg",editedByType:"Edited by",editors:[{id:"24555",title:"Dr.",name:"Marco Antonio",surname:"Aceves-Fernandez",slug:"marco-antonio-aceves-fernandez",fullName:"Marco Antonio Aceves-Fernandez"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],ofsBooks:[]},correction:{item:{id:"72877",slug:"erratum-synthesis-techniques-and-applications-of-perovskite-materials",title:"Erratum - Synthesis Techniques and Applications of Perovskite Materials",doi:null,correctionPDFUrl:"https://cdn.intechopen.com/pdfs/72877.pdf",downloadPdfUrl:"/chapter/pdf-download/72877",previewPdfUrl:"/chapter/pdf-preview/72877",totalDownloads:null,totalCrossrefCites:null,bibtexUrl:"/chapter/bibtex/72877",risUrl:"/chapter/ris/72877",chapter:{id:"70923",slug:"synthesis-techniques-and-applications-of-perovskite-materials",signatures:"Dinesh Kumar, Ram Sagar Yadav, Monika, Akhilesh Kumar Singh and Shyam Bahadur Rai",dateSubmitted:"March 12th 2019",dateReviewed:"May 13th 2019",datePrePublished:null,datePublished:"June 10th 2020",book:{id:"9360",title:"Perovskite Materials, Devices and Integration",subtitle:null,fullTitle:"Perovskite Materials, Devices and Integration",slug:"perovskite-materials-devices-and-integration",publishedDate:"June 10th 2020",bookSignature:"He Tian",coverURL:"https://cdn.intechopen.com/books/images_new/9360.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"259466",title:"Prof.",name:"He",middleName:null,surname:"Tian",slug:"he-tian",fullName:"He Tian"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"298428",title:"Dr.",name:"Ram Sagar",middleName:null,surname:"Yadav",fullName:"Ram Sagar Yadav",slug:"ram-sagar-yadav",email:"ramsagaryadav@gmail.com",position:null,institution:null},{id:"302651",title:"Mr.",name:"Dinesh",middleName:null,surname:"Kumar",fullName:"Dinesh Kumar",slug:"dinesh-kumar",email:"dineshiitbhu@gmail.com",position:null,institution:null},{id:"302652",title:"Ms.",name:"Monika",middleName:null,surname:"Kanwal",fullName:"Monika Kanwal",slug:"monika-kanwal",email:"monikavbspu@gmail.com",position:null,institution:null},{id:"302653",title:"Dr.",name:"Akhilesh Kumar",middleName:null,surname:"Singh",fullName:"Akhilesh Kumar Singh",slug:"akhilesh-kumar-singh",email:"aksingh.mst@iitbhu.ac.in",position:null,institution:null},{id:"302654",title:"Prof.",name:"Shyam Bahadur",middleName:null,surname:"Rai",fullName:"Shyam Bahadur Rai",slug:"shyam-bahadur-rai",email:"sbrai49@yahoo.co.in",position:null,institution:null}]}},chapter:{id:"70923",slug:"synthesis-techniques-and-applications-of-perovskite-materials",signatures:"Dinesh Kumar, Ram Sagar Yadav, Monika, Akhilesh Kumar Singh and Shyam Bahadur Rai",dateSubmitted:"March 12th 2019",dateReviewed:"May 13th 2019",datePrePublished:null,datePublished:"June 10th 2020",book:{id:"9360",title:"Perovskite Materials, Devices and Integration",subtitle:null,fullTitle:"Perovskite Materials, Devices and Integration",slug:"perovskite-materials-devices-and-integration",publishedDate:"June 10th 2020",bookSignature:"He Tian",coverURL:"https://cdn.intechopen.com/books/images_new/9360.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"259466",title:"Prof.",name:"He",middleName:null,surname:"Tian",slug:"he-tian",fullName:"He Tian"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}},authors:[{id:"298428",title:"Dr.",name:"Ram Sagar",middleName:null,surname:"Yadav",fullName:"Ram Sagar Yadav",slug:"ram-sagar-yadav",email:"ramsagaryadav@gmail.com",position:null,institution:null},{id:"302651",title:"Mr.",name:"Dinesh",middleName:null,surname:"Kumar",fullName:"Dinesh Kumar",slug:"dinesh-kumar",email:"dineshiitbhu@gmail.com",position:null,institution:null},{id:"302652",title:"Ms.",name:"Monika",middleName:null,surname:"Kanwal",fullName:"Monika Kanwal",slug:"monika-kanwal",email:"monikavbspu@gmail.com",position:null,institution:null},{id:"302653",title:"Dr.",name:"Akhilesh Kumar",middleName:null,surname:"Singh",fullName:"Akhilesh Kumar Singh",slug:"akhilesh-kumar-singh",email:"aksingh.mst@iitbhu.ac.in",position:null,institution:null},{id:"302654",title:"Prof.",name:"Shyam Bahadur",middleName:null,surname:"Rai",fullName:"Shyam Bahadur Rai",slug:"shyam-bahadur-rai",email:"sbrai49@yahoo.co.in",position:null,institution:null}]},book:{id:"9360",title:"Perovskite Materials, Devices and Integration",subtitle:null,fullTitle:"Perovskite Materials, Devices and Integration",slug:"perovskite-materials-devices-and-integration",publishedDate:"June 10th 2020",bookSignature:"He Tian",coverURL:"https://cdn.intechopen.com/books/images_new/9360.jpg",licenceType:"CC BY 3.0",editedByType:"Edited by",editors:[{id:"259466",title:"Prof.",name:"He",middleName:null,surname:"Tian",slug:"he-tian",fullName:"He Tian"}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"}}},ofsBook:{item:{type:"book",id:"8804",leadTitle:null,title:"Water and Wastewater Treatment",subtitle:null,reviewType:"peer-reviewed",abstract:"The use of water, one of the most valuable and vital resources in the world, should respond to growing needs, and used water should not have negative effects on the environment. Research on the reduction of used water and wastewater quantities, post-use treatment, or reuse/recovery methods is increasing day by day. These studies focus on finding the most appropriate method from both technical and economic perspectives. In this book, emerging technologies and materials used in the treatment, reuse, or recovery of various kinds of water and wastewaters are examined. The book consists of valuable scientific research specifically including desalination and use of renewable energy, nanomaterials, biosorbents, photocatalytic treatment, as well as riverbank filtration and wetlands. The editor would like to record his sincere thanks to the authors for their contributions.",isbn:"978-1-78923-930-0",printIsbn:"978-1-78923-929-4",pdfIsbn:"978-1-78984-688-1",doi:"10.5772/intechopen.80313",price:119,priceEur:129,priceUsd:155,slug:"water-and-wastewater-treatment",numberOfPages:160,isOpenForSubmission:!1,hash:"ccb46d6518786712b3184b2498fb0cab",bookSignature:"Murat Eyvaz",publishedDate:"July 24th 2019",coverURL:"https://cdn.intechopen.com/books/images_new/8804.jpg",keywords:null,numberOfDownloads:4305,numberOfWosCitations:0,numberOfCrossrefCitations:2,numberOfDimensionsCitations:15,numberOfTotalCitations:17,isAvailableForWebshopOrdering:!0,dateEndFirstStepPublish:"September 5th 2018",dateEndSecondStepPublish:"September 26th 2018",dateEndThirdStepPublish:"November 25th 2018",dateEndFourthStepPublish:"February 13th 2019",dateEndFifthStepPublish:"April 14th 2019",remainingDaysToSecondStep:"2 years",secondStepPassed:!0,currentStepOfPublishingProcess:5,editedByType:"Edited by",kuFlag:!1,biosketch:null,coeditorOneBiosketch:null,coeditorTwoBiosketch:null,coeditorThreeBiosketch:null,coeditorFourBiosketch:null,coeditorFiveBiosketch:null,editors:[{id:"170083",title:"Associate Prof.",name:"Murat",middleName:null,surname:"Eyvaz",slug:"murat-eyvaz",fullName:"Murat Eyvaz",profilePictureURL:"https://mts.intechopen.com/storage/users/170083/images/system/170083.jpeg",biography:"Dr. Eyvaz is an Associate Professor of the Environmental Engineering Department (ENVE) at Gebze Technical University (GTU). He received his bachelor’s degree in environmental engineering from Kocaeli University in Turkey in 2004. He completed his graduate work (M.Sc., 2006 and Ph.D., 2013) at Gebze Institute of Technology (former name of GTU) in Environmental Engineering under the supervision of Dr. Mehmet KOBYA, Prof. in ENVE-GTU (for M.Sc.), and of Dr. Ebubekir YÜKSEL, Prof. in ENVE-GTU and Dr. Ömer AKGİRAY, Professor and Chair of ENVE at Marmara University, (for Ph. D.). He completed his post-doctoral research in the National Research Center on Membrane Technologies (in Istanbul Technical University) under the mentorship of Dr. İsmail KOYUNCU, Professor and Manager of the center, between March 2014-March 2015.\n\nDr. Eyvaz has been in the Environmental Engineering Department of GTU as a Faculty Member (2017-present). His research interests are applications in water and wastewater treatment facilities, electrochemical treatment process, and filtration systems at the lab. and pilot scale, membrane processes (forward osmosis, reverse osmosis, membrane bioreactors), membrane manufacturing methods (polymeric membranes, nanofiber membranes, electrospinning), spectrophotometric analyses (UV, atomic absorption spectrophotometry), chromatographic analyses (gas chromatography, high-pressure liquid chromatography). He has published his findings in the premier journals of his field, Journal of Hazardous Materials, Separation and Purification Technology, Journal of Membrane Science, and Chemical Engineering Journal. He has produced more than 20 peer-reviewed publications (cited over 1000 times) with an h index of 12. He serves as an editor for over 45 various journals and a reviewer in 140 different various journals and conferences indexed in SCI, SCI-E, and other indexes.\n\nDr. Eyvaz and his co-authors’ peer-reviewed publications have continuously and increasingly been cited. By January 2021, the totals of citations to Dr. Eyvaz’s journal publications are 555, 599, and 1055 for Web of Science, Scopus, and Google Scholars databases, respectively, and his h-indexes are 10, 10, and 12, respectively.",institutionString:"Gebze Technical University",position:null,outsideEditionCount:0,totalCites:0,totalAuthoredChapters:"5",totalChapterViews:"0",totalEditedBooks:"6",institution:{name:"Gebze Technical University",institutionURL:null,country:{name:"Turkey"}}}],coeditorOne:null,coeditorTwo:null,coeditorThree:null,coeditorFour:null,coeditorFive:null,topics:[{id:"1354",title:"Wastewater Engineering",slug:"technology-environmental-engineering-wastewater-engineering"}],chapters:[{id:"66885",title:"Treatment of Water and Wastewater for Reuse and Energy Generation-Emerging Technologies",slug:"treatment-of-water-and-wastewater-for-reuse-and-energy-generation-emerging-technologies",totalDownloads:1291,totalCrossrefCites:1,authors:[{id:"199957",title:"Dr.",name:"Sudesh",surname:"Rathilal",slug:"sudesh-rathilal",fullName:"Sudesh Rathilal"},{id:"262983",title:"Dr.",name:"Emmanuel",surname:"Kweinor Tetteh",slug:"emmanuel-kweinor-tetteh",fullName:"Emmanuel Kweinor Tetteh"},{id:"281613",title:"Dr.",name:"Maggie",surname:"Chetty",slug:"maggie-chetty",fullName:"Maggie Chetty"},{id:"281614",title:"Mr.",name:"Edward Kwaku",surname:"Armah",slug:"edward-kwaku-armah",fullName:"Edward Kwaku Armah"},{id:"281615",title:"Dr.",name:"Dennis",surname:"Asante-Sackey",slug:"dennis-asante-sackey",fullName:"Dennis Asante-Sackey"}]},{id:"66331",title:"Desalination with Renewable Energy: A 24 Hours Operation Solution",slug:"desalination-with-renewable-energy-a-24-hours-operation-solution",totalDownloads:632,totalCrossrefCites:0,authors:[{id:"174208",title:"Dr.",name:"Muhammad Wakil",surname:"Shahzad",slug:"muhammad-wakil-shahzad",fullName:"Muhammad Wakil Shahzad"}]},{id:"65548",title:"Nonconventional Wastewater Treatment for the Degradation of Fuel Oxygenated (MTBE, ETBE, and TAME)",slug:"nonconventional-wastewater-treatment-for-the-degradation-of-fuel-oxygenated-mtbe-etbe-and-tame-",totalDownloads:355,totalCrossrefCites:1,authors:[{id:"228497",title:"Dr.",name:"Hermicenda",surname:"Perez Vidal",slug:"hermicenda-perez-vidal",fullName:"Hermicenda Perez Vidal"},{id:"229146",title:"Dr.",name:"Zenaida",surname:"Guerra Que",slug:"zenaida-guerra-que",fullName:"Zenaida Guerra Que"},{id:"240565",title:"Dr.",name:"Jose Gilberto",surname:"Torres Torres",slug:"jose-gilberto-torres-torres",fullName:"Jose Gilberto Torres Torres"},{id:"240661",title:"Dr.",name:"María A.",surname:"Lunagómez Rocha",slug:"maria-a.-lunagomez-rocha",fullName:"María A. Lunagómez Rocha"},{id:"240664",title:"Dr.",name:"Alejandra E.",surname:"Espinosa De Los Monteros Reyna",slug:"alejandra-e.-espinosa-de-los-monteros-reyna",fullName:"Alejandra E. Espinosa De Los Monteros Reyna"},{id:"278081",title:"Dr.",name:"Ignacio",surname:"Cuauhtemoc Lopez",slug:"ignacio-cuauhtemoc-lopez",fullName:"Ignacio Cuauhtemoc Lopez"},{id:"278082",title:"Dr.",name:"Adrian",surname:"Cervantes Uribe",slug:"adrian-cervantes-uribe",fullName:"Adrian Cervantes Uribe"},{id:"278083",title:"MSc.",name:"Juan Carlos",surname:"Arevalo Perez",slug:"juan-carlos-arevalo-perez",fullName:"Juan Carlos Arevalo Perez"},{id:"278085",title:"Dr.",name:"Jose Guadalupe",surname:"Pacheco Sosa",slug:"jose-guadalupe-pacheco-sosa",fullName:"Jose Guadalupe Pacheco Sosa"},{id:"286928",title:"MSc.",name:"Cecilia",surname:"Sánchez Trinidad",slug:"cecilia-sanchez-trinidad",fullName:"Cecilia Sánchez Trinidad"}]},{id:"65531",title:"Removal of Cr(VI) from Waters by Multi-Walled Carbon Nanotubes: Optimization and Kinetic Investigations",slug:"removal-of-cr-vi-from-waters-by-multi-walled-carbon-nanotubes-optimization-and-kinetic-investigation",totalDownloads:386,totalCrossrefCites:0,authors:[{id:"51571",title:"Dr.",name:"Francisco Jose",surname:"Alguacil",slug:"francisco-jose-alguacil",fullName:"Francisco Jose Alguacil"},{id:"225960",title:"Prof.",name:"Félix A.",surname:"López",slug:"felix-a.-lopez",fullName:"Félix A. López"}]},{id:"65541",title:"Advances in Metal Recovery from Wastewaters Using Selected Biosorbent Materials and Constructed Wetland Systems",slug:"advances-in-metal-recovery-from-wastewaters-using-selected-biosorbent-materials-and-constructed-wetl",totalDownloads:514,totalCrossrefCites:0,authors:[{id:"173356",title:"Prof.",name:"Tony",surname:"Pembroke",slug:"tony-pembroke",fullName:"Tony Pembroke"},{id:"277214",title:"Dr.",name:"John",surname:"Murnane",slug:"john-murnane",fullName:"John Murnane"},{id:"277892",title:"Dr.",name:"Tom",surname:"O'Dwyer",slug:"tom-o'dwyer",fullName:"Tom O'Dwyer"},{id:"277893",title:"Dr.",name:"Bashir",surname:"Ghanim",slug:"bashir-ghanim",fullName:"Bashir Ghanim"},{id:"277894",title:"Dr.",name:"Ronan",surname:"Courtney",slug:"ronan-courtney",fullName:"Ronan Courtney"},{id:"288164",title:"Dr.",name:"Lisa",surname:"O'Donoghue",slug:"lisa-o'donoghue",fullName:"Lisa O'Donoghue"}]},{id:"66516",title:"Removal of Escherichia Coli Using Low-Frequency Electromagnetic Field in Riverbank Filtration",slug:"removal-of-em-escherichia-coli-em-using-low-frequency-electromagnetic-field-in-riverbank-filtration",totalDownloads:459,totalCrossrefCites:0,authors:[{id:"288966",title:"Ph.D. Student",name:"Rossitah",surname:"Selamat",slug:"rossitah-selamat",fullName:"Rossitah Selamat"}]},{id:"65818",title:"Photocatalytic Treatment of Pesticides Using TiO2 Doped with Rare Earth",slug:"photocatalytic-treatment-of-pesticides-using-tio-sub-2-sub-doped-with-rare-earth",totalDownloads:367,totalCrossrefCites:0,authors:[{id:"228497",title:"Dr.",name:"Hermicenda",surname:"Perez Vidal",slug:"hermicenda-perez-vidal",fullName:"Hermicenda Perez Vidal"},{id:"229146",title:"Dr.",name:"Zenaida",surname:"Guerra Que",slug:"zenaida-guerra-que",fullName:"Zenaida Guerra Que"},{id:"240565",title:"Dr.",name:"Jose Gilberto",surname:"Torres Torres",slug:"jose-gilberto-torres-torres",fullName:"Jose Gilberto Torres Torres"},{id:"240661",title:"Dr.",name:"María A.",surname:"Lunagómez Rocha",slug:"maria-a.-lunagomez-rocha",fullName:"María A. Lunagómez Rocha"},{id:"240662",title:"MSc.",name:"Juan C.",surname:"Arévalo Pérez",slug:"juan-c.-arevalo-perez",fullName:"Juan C. Arévalo Pérez"},{id:"240663",title:"Dr.",name:"Ignacio",surname:"Cuauhtémoc López",slug:"ignacio-cuauhtemoc-lopez",fullName:"Ignacio Cuauhtémoc López"},{id:"279703",title:"Dr.",name:"Durvel",surname:"De La Cruz Romero",slug:"durvel-de-la-cruz-romero",fullName:"Durvel De La Cruz Romero"}]},{id:"64595",title:"Assessment of Microbial Load Reduction Efficiency of Sewage Treatment Plants (STP’s) in Mysore, Karnataka, India",slug:"assessment-of-microbial-load-reduction-efficiency-of-sewage-treatment-plants-stp-s-in-mysore-karnata",totalDownloads:301,totalCrossrefCites:0,authors:[{id:"236037",title:"Dr.",name:"Jessen",surname:"George",slug:"jessen-george",fullName:"Jessen George"},{id:"276370",title:"Dr.",name:"Shivaraju",surname:"Harikaranahalli Puttaiah",slug:"shivaraju-harikaranahalli-puttaiah",fullName:"Shivaraju Harikaranahalli Puttaiah"},{id:"278782",title:"Mr.",name:"Ashili",surname:"Severeni",slug:"ashili-severeni",fullName:"Ashili Severeni"}]}],productType:{id:"1",title:"Edited Volume",chapterContentType:"chapter",authoredCaption:"Edited by"},personalPublishingAssistant:{id:"177731",firstName:"Dajana",lastName:"Pemac",middleName:null,title:"Ms.",imageUrl:"https://mts.intechopen.com/storage/users/177731/images/4726_n.jpg",email:"dajana@intechopen.com",biography:"As a Commissioning Editor at IntechOpen, I work closely with our collaborators in the selection of book topics for the yearly publishing plan and in preparing new book catalogues for each season. This requires extensive analysis of developing trends in scientific research in order to offer our readers relevant content. Creating the book catalogue is also based on keeping track of the most read, downloaded and highly cited chapters and books and relaunching similar topics. I am also responsible for consulting with our Scientific Advisors on which book topics to add to our catalogue and sending possible book proposal topics to them for evaluation. Once the catalogue is complete, I contact leading researchers in their respective fields and ask them to become possible Academic Editors for each book project. Once an editor is appointed, I prepare all necessary information required for them to begin their work, as well as guide them through the editorship process. I also assist editors in inviting suitable authors to contribute to a specific book project and each year, I identify and invite exceptional editors to join IntechOpen as Scientific Advisors. I am responsible for developing and maintaining strong relationships with all collaborators to ensure an effective and efficient publishing process and support other departments in developing and maintaining such relationships."}},relatedBooks:[{type:"book",id:"6732",title:"Desalination and Water Treatment",subtitle:null,isOpenForSubmission:!1,hash:"eee2f03e0328f289e68fde28738c333f",slug:"desalination-and-water-treatment",bookSignature:"Murat Eyvaz and Ebubekir Yüksel",coverURL:"https://cdn.intechopen.com/books/images_new/6732.jpg",editedByType:"Edited by",editors:[{id:"170083",title:"Associate Prof.",name:"Murat",surname:"Eyvaz",slug:"murat-eyvaz",fullName:"Murat Eyvaz"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6665",title:"Advances In Hydrogen Generation Technologies",subtitle:null,isOpenForSubmission:!1,hash:"99ccb9f2118953ff45f33ec391868157",slug:"advances-in-hydrogen-generation-technologies",bookSignature:"Murat Eyvaz",coverURL:"https://cdn.intechopen.com/books/images_new/6665.jpg",editedByType:"Edited by",editors:[{id:"170083",title:"Associate Prof.",name:"Murat",surname:"Eyvaz",slug:"murat-eyvaz",fullName:"Murat Eyvaz"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7237",title:"Energy-Efficient Approaches in Industrial Applications",subtitle:null,isOpenForSubmission:!1,hash:"a7b403a3af7828987f078b91334839bb",slug:"energy-efficient-approaches-in-industrial-applications",bookSignature:"Murat Eyvaz, Abdülkerim Gok and Ebubekir Yüksel",coverURL:"https://cdn.intechopen.com/books/images_new/7237.jpg",editedByType:"Edited by",editors:[{id:"170083",title:"Associate Prof.",name:"Murat",surname:"Eyvaz",slug:"murat-eyvaz",fullName:"Murat Eyvaz"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8178",title:"Water Chemistry",subtitle:null,isOpenForSubmission:!1,hash:"18595695f271583e06b7c2d33b670e56",slug:"water-chemistry",bookSignature:"Murat Eyvaz and Ebubekir Yüksel",coverURL:"https://cdn.intechopen.com/books/images_new/8178.jpg",editedByType:"Edited by",editors:[{id:"170083",title:"Associate Prof.",name:"Murat",surname:"Eyvaz",slug:"murat-eyvaz",fullName:"Murat Eyvaz"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7693",title:"Green Chemistry Applications",subtitle:null,isOpenForSubmission:!1,hash:"9db61c9d52045d034f1ee6b769acccd5",slug:"green-chemistry-applications",bookSignature:"Murat Eyvaz and Ebubekir Yüksel",coverURL:"https://cdn.intechopen.com/books/images_new/7693.jpg",editedByType:"Edited by",editors:[{id:"170083",title:"Associate Prof.",name:"Murat",surname:"Eyvaz",slug:"murat-eyvaz",fullName:"Murat Eyvaz"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6539",title:"Wastewater and Water Quality",subtitle:null,isOpenForSubmission:!1,hash:"011810f6bbc0d25f6590e1169231962f",slug:"wastewater-and-water-quality",bookSignature:"Taner Yonar",coverURL:"https://cdn.intechopen.com/books/images_new/6539.jpg",editedByType:"Edited by",editors:[{id:"32956",title:"Dr.",name:"Taner",surname:"Yonar",slug:"taner-yonar",fullName:"Taner Yonar"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"6199",title:"Osmotically Driven Membrane Processes",subtitle:"Approach, Development and Current Status",isOpenForSubmission:!1,hash:"bbb718c2b4705962a3388b4cb551d87b",slug:"osmotically-driven-membrane-processes-approach-development-and-current-status",bookSignature:"Hongbo Du, Audie Thompson and Xinying Wang",coverURL:"https://cdn.intechopen.com/books/images_new/6199.jpg",editedByType:"Edited by",editors:[{id:"180165",title:"Dr.",name:"Hongbo",surname:"Du",slug:"hongbo-du",fullName:"Hongbo Du"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"7645",title:"Desalination",subtitle:"Challenges and Opportunities",isOpenForSubmission:!1,hash:"79498ce21a56d214786502c9fe4ebd6b",slug:"desalination-challenges-and-opportunities",bookSignature:"Mohammad Hossein Davood Abadi Farahani, Vahid Vatanpour and Amir Hooshang Taheri",coverURL:"https://cdn.intechopen.com/books/images_new/7645.jpg",editedByType:"Edited by",editors:[{id:"249503",title:"Dr.",name:"Mohammad Hossein",surname:"Davood Abadi Farahani",slug:"mohammad-hossein-davood-abadi-farahani",fullName:"Mohammad Hossein Davood Abadi Farahani"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9415",title:"Advanced Oxidation Processes",subtitle:"Applications, Trends, and Prospects",isOpenForSubmission:!1,hash:"60d177837fbb691b82c80922cd9bb295",slug:"advanced-oxidation-processes-applications-trends-and-prospects",bookSignature:"Ciro Bustillo-Lecompte",coverURL:"https://cdn.intechopen.com/books/images_new/9415.jpg",editedByType:"Edited by",editors:[{id:"189304",title:"Dr.",name:"Ciro",surname:"Bustillo-Lecompte",slug:"ciro-bustillo-lecompte",fullName:"Ciro Bustillo-Lecompte"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8915",title:"Advances in Membrane Technologies",subtitle:null,isOpenForSubmission:!1,hash:"19febde893f705494f2334d02977fd83",slug:"advances-in-membrane-technologies",bookSignature:"Amira Abdelrasoul",coverURL:"https://cdn.intechopen.com/books/images_new/8915.jpg",editedByType:"Edited by",editors:[{id:"151521",title:"Dr.",name:"Amira",surname:"Abdelrasoul",slug:"amira-abdelrasoul",fullName:"Amira Abdelrasoul"}],productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},chapter:{item:{type:"chapter",id:"41544",title:"Diagnosis of Gastritis – Review from Early Pathological Evaluation to Present Day Management",doi:"10.5772/52884",slug:"diagnosis-of-gastritis-review-from-early-pathological-evaluation-to-present-day-management",body:'
The gastritis is an inflammatory condition of the gastric mucosa characterized by existence of elementary histological alternations. However these structural changes observed by the pioneer of gastric histology were noted more than a century ago, their etiology and proper interpretation for clinical practice required much longer time.
The ancient Egyptians wrote that the diseases of internal organs are difficult to detect even in well-preserved bodies, hence they were not able to comprehend outstanding discoveries on the stomach as they did on other organ diseases. The first major discovery in the field of gastric diseases was the description of gastric cancer by the Persian Avicenna around 1000 (quoted by Rugge et al, 2003). At the same time the discoveries of non-neoplastic gastric diseases, especially gastritis, was really elusive for quite a long time due to less macroscopic features and to post-mortem alternations. The inflammation of the inner lining of the stomach was first noted as “gastritis” by a German physician, Georg Ernst Stahl in 1728 (quoted by Bock, 1974). Italian anatomical pathologist Giovanni Battista Morgagni further described the signs of gastric inflammation. He gave the first classical description of an erosive or ulcerating gastritis. He stated that some of the erosions can become gangrenous, and described corrosive gastritis as it was the most well-known gastritis form of that time due high number of lye intoxication. French physician, François-Joseph-Victor Broussais gathering information by autopsy of dead French soldiers between 1808 and 1831, described common chronic gastritis as he called “Gastritides”, and sometimes got delusive conclusions as gastritis was the cause of ascites and other diseases, like typhoid fever and meningitis (Bock, 1974). Jones Handfield and Wilson Fox (1854) described microscopic changes of mucous membrane in gastric inflammation, which exists in diffuse and segmental forms. Not much later another British physician, William Brinton (1859) emphasized the symptomatic and microscopic differences of acut, subacute and chronic gastritis in his medical book entitled “Diseases of Stomach”, and described haemorrhagic erosion and follicular ulceration. Meanwhile Baron Carl von Rokitansky besides his major discoveries was the first to note hypertrophic gastritis in 1855. The next major footstep was done by Samuel Fenwick in 1870, who noted the presence of glandular atrophy due to gastric inflammation when classifying gastric lesions and anatomical alternations of the gastric mucosa (Fenwick, 1870). He also discovered that pernicious anaemia is associated with gastric mucosal atrophy. German surgeon, Georg Ernst Konjetzny using surgical specimens showed first that both gastric ulcer and gastric cancer are either secondary diseases or are associated in their pathogenesis to chronic gastric inflammation. Shields Warren and Willam A. Meissner described intestinal metaplasia of the stomach. They noted intestinal metaplasia as a feature of chronic gastritis, and found seldom extensive in duodenal ulcer patients, while it was extensive in stomachs removed due to carcinoma (Warren & Meissner, 1944; Rugge et al, 2003).
In vivo diagnosis of gastritis got a huge drive with the development of routine gastroscopy. By the 1950’s, Rudolf Schindler’s part-flexible endoscopes became very common making rigid endoscopes to disappear. From 1960’s, the commercial introduction of flexible endoscopes gave easy access for gastric biopsy and diagnosis of gastritis (Palmer, 1956). By the use of biopsy based histology Schindler gave overview of gastritis in his monograph entitled ‘Gastritis’ in 1947, he divided inflammation into ‘superficial’, ‘atrophic’ and ‘hypertrophic’ gastritis chronica (Schindler, 1947). Cheli and Dobero in 1958 differentiated ‘superficial’, ‘interstitial’ and ‘atrophic gastritis’ in the terminology of gastric inflammatory lesions (Cheli & Dobero, 1956). Up to his time classifications lack topography, but in 1972, Whitehead distinguished antral, fonical, corporal and pyloric region inflammation based on classical pathomorphology. Whitehead divided chronic gastritis into ‘superficial’ and ‘atrophic’, both ‘active’ or ‘in-active’ based on the presence of granulocyte infiltration in epithelium and interstitium beside the inflammatory infiltration of lamina propria from lymphocytes and plasmatic cells (Whitehead et al, 1972). He suggested the use of a mild-moderate-severe scale to evaluate the atrophy. He also introduced the evaluation of intestinal and pseudopyloric metaplasia into everyday pathological assessment.
Based on recent research data, Robert G. Strickland and Ian R. MacKay proposed the classification of gastritis based on additional factors just beside just histology and topography (Strickland & Mackay, 1973). They suggested that immunological and etiological data should be included along with pathomorphological and topographic parameters; gastric parietal cell antibody and serum level of gastrin have to be seen to get better classification of chronic gastritis. They used the term ‘Type A gastritis’ for gastric corporal inflammation mostly corresponding to pernicious anaemia, and ‘Type B’ for antral gastritis suspected to be induced by duodeno-gastric reflux according to some thoughts. In 1975 George B Jerzy Glass and Capecomorin S. Pitchumoni added the ‘Type AB’ to the classification. This term was aimed to be used for extended gastritis observed in corpus to pre-pyloric region (Glass & Pitchumoni, 1975). Those cases were named ‘AB-plus’ where antibody positivity was also founds against parietal cells. In 1980, the classification was further modified by Correa dividing chronic gastritis into autoimmune chronic gastritis with pernicious anaemia, ‘hypersecretory’ and ‘environmental’ forms. He described the gastritis accompanying ulcer to hypersecretory. All the rest of gastritis was called environmental, which are mostly due to diet and geographic localization (Correa, 1980). Later as more data were known from histological assessments, he changed his classification for ‘diffuse antral’, ‘diffuse corporal’ and ‘multifocal’ gastritis. By seeing his nomenclature, sometimes showing etiology, sometimes reflecting topography, we are able to see the controversy existed between pathologist and clinicians in the field of gastritis at that time. The extensiveness in topography along with histological and etiologic features were not to be combined in an uniformed nomenclature, even Correa in 1988 returned to his previous version of classification (Correa, 1988). Later, he went to different direction by dividing gastritis into two major categories of ‘atrophic’ and ‘non-atrophic’ gastritis.
The next major step was added by Judith I. Wyatt and Michael F. Dixon by the introduction of ‘type C’ gastritis for chemical (drug)-induced inflammation of gastric mucosa (Wyatt & Dixon, 1988). Two years later, examining 316 patients Sobala confirmed that most of reflux gastritis in intact (non-operated) stomach is not due to bile reflux but rather NSAID use. According to their proposition the term ‘type C’ or ‘chemical’ gastritis might be used for condition caused by both etiology (Sobala et al, 1990).
Modern aspects of gastritis classification and knowledge of its biological course and consequences were relatively well-known at the time when Helicobacter pylori (H. pylori) was discovered by Robin Warren and Barry Marshall in 1982 (Warren & Marshall, 1983). Their discovery showed that the commonest form of gastritis is simply an infectious disease caused by an otherwise known pathogen. At that time gastroenterologist and pathologist had limited knowledge on even simple aspects of this chronic bacterial inflammation of gastric mucosa and the classification system used was confusing and differing from county to another. Very soon considerable amount of data became known about H. pylori, its disease associations and their natural courses by many physicians, microbiologist and basic researchers entering the field. As a consequence in the late 1980\'s several pre-meeting of Working Party (Anthony Axon, Wladimir Bogomoletz, Michael F. Dixon, Steart Goodwin, Jules Haot, Konrad L. Heilmann, Adrian Lee, Barry Marshall, George Misiewicz, Ashley Price, Penti Sipponen, Enrico Solcia, Manfred Stolte, Robert Strickland, Guido Tytgat) was set up to review the biology and natural course of chronic gastritis and to propose a new classification for gastritis by the leadership of George Misiewicz and Guido Tytgat. The working party actually consisted of two groups mainly working parallel to another: as a pathological group and a clinical group (Sipponen & Price, 2011). Based on new etiological facts and data collected, a new system of classification was presented at the World Congress of Gastroenterology held in Sydney, Australia in 1990, and subsequently published as six papers in the Journal Gastroenterology and Hepatology. The existence of the two Working Parties reflects on the histological and endoscopic division of Sydney System. The histological division of Sydney System intended to be a practical guideline showing which of the morphological features of gastritis in endoscopic biopsy specimens should be documented (Price, 1991). Type, severity and extent of gastric inflammation linked to possible etiology should be detailed according to a chart designed (see Fig. 1). The Sydney System declared the routine biopsy sampling protocol, the number of biopsies should be taken, the biopsies’ proper localisation (two from antrum and two from corpus, both from anterior and posterior walls) and sample fixation in adequately labelled separate containers (Misiewicz et al, 1990; Price & Misiewicz, 1991). Many pathologist think to these last as the most important conclusions of the system. The system also established a four-level scale for defining severity (extent) of pathomorphological elements.
Chart designed for the histological division of the original Sydney System as presented to the World Congress of Gastroenterology. Published in Journal of Gastroenterology and Hepatology in 1991. Describes the nomenclature should be used in histological reporting of gastritis. Adopted etiological suffix phrases to topography and morphological features with grading suffixes to be documented in endoscopic biopsy reporting.
\n\t\t\t\tYear\n\t\t\t | \n\t\t\t\n\t\t\t\tAuthor/Classification\n\t\t\t | \n\t\t\t\n\t\t\t\tComment\n\t\t\t | \n\t\t
1728 | \n\t\t\tStahl | \n\t\t\t‘Gastritis’ defined (quoted by Bock, 1974) | \n\t\t
1771 | \n\t\t\tMorgagni | \n\t\t\t’Erosive’ and ’ulcerating gastritis’’ described (Crawford et al, 1932) | \n\t\t
1859 | \n\t\t\tWilliam Brinton | \n\t\t\tAcute, subacute and chronic gastritis differentiated □ | \n\t\t
1855 | \n\t\t\tRokitansky | \n\t\t\tHypertrophic gastritis described (quoted by Vaugham, 1945). | \n\t\t
1870 | \n\t\t\tFenwik | \n\t\t\tGastric atrophy described □ | \n\t\t
1944 | \n\t\t\tWarren & Meissner | \n\t\t\tIntestinal metaplasia described □ | \n\t\t
1947 | \n\t\t\tWood | \n\t\t\tFirst gastric biopsy, ‘Gastritis’ defined (Wood et al, 1949) | \n\t\t
1956 | \n\t\t\tCheli & Dobero ¤ | \n\t\t\tSuperficial, Interstitial and Atrophic gastritis □ | \n\t\t
1956 | \n\t\t\tEder-Palmer ∇ | \n\t\t\tIntroduction of flexible fibre optic endoscope (Palmer, 1956) | \n\t\t
1972 | \n\t\t\tWhitehead ¤ | \n\t\t\tSuperficial, Atrophic, both ‘Active’ or ‘In-active’. Type and Stage of activity. Presence and type of metaplasia □ | \n\t\t
1973 | \n\t\t\tStrickland & MacKay ¤ | \n\t\t\tA (autoimmune) PCA+ in 95% and IFA+ in 75%, B (nonautoimmune = environmental) □ | \n\t\t
1975 | \n\t\t\tPitchumoni ¤ | \n\t\t\tA (autoimmune-corpus), B (antrum), AB (both antrum and corpus) PCA+ or - (Glass & Pitchumoni, 1975) | \n\t\t
1980 | \n\t\t\tCorrea ¤ | \n\t\t\tAutoimmune, Hypersecretory, Environmental □ | \n\t\t
1988 | \n\t\t\tCorrea ¤ | \n\t\t\tDiffuse corporal (autoimmune), Chr. diffuse antral, Multifocal environmental, Chr. Superficial, Lymphocytic, Postgastrectomy □ | \n\t\t
1989 | \n\t\t\tOwen ¤ | \n\t\t\tChr. non-specific type A, Chr. non-specific type B □ | \n\t\t
1990 | \n\t\t\tYardley ¤ | \n\t\t\tH. pylori gastritis, Metaplastic atrophic (type A, autoimmune), Metaplastic atrophic (type B), Lymphocytic, Chemical □ | \n\t\t
1990 | \n\t\t\tDixon ¤ | \n\t\t\t’Type C’ proposed to reactive gastric lesions □ | \n\t\t
1990 | \n\t\t\tSobala | \n\t\t\tReflux gastritis defined as type C gastritis □ | \n\t\t
1990 | \n\t\t\tSydney ¤ | \n\t\t\tNonatrophic, Atrophic (Autoimmune, Multifocal), Special forms. Four-level scale, proper biopsy sampling & handling, standard reporting aiming etiology (Misiewicz et al, 1990) | \n\t\t
1994 | \n\t\t\tAppelman ¤ | \n\t\t\tAcute or Chronic; Helicobacter type, Atrophic (type A, type B), Lymphocytic, Focal & miscellaneous, Chemical gastropathies □ | \n\t\t
1996 | \n\t\t\tUp-dated Sydney ¤ | \n\t\t\tBiopsy location changed from anterior and posterior wall to greater and lesser curvature (Dixon et al, 1996) | \n\t\t
2000 | \n\t\t\tPadova ¤ | \n\t\t\tClassification of dysplasia and related lesions (Rugge et al, 2000) | \n\t\t
2005 | \n\t\t\tOLGA ¤ | \n\t\t\tClassification of grading mucosal atrophy (Rugge et al, 2005b) | \n\t\t
History of Classification of Gastritis.
◦ Classification (system) ∇ Manufacturer □ See ref. under same name and year
The Sydney System which actually allowed statements to be made on etiology, topography and morphology of gastritis for the first time, was not accepted everywhere immediately, especially in the United States. The main criticism was that the some of the commonly used descriptive names were not enabled into the system, like the ‘multifocal atrophic gastritis’ or ‘diffuse antral gastritis’. Although, by that time it was already accepted that the Sydney System was not designed to be the textbook of gastric pathology, but to be a guide for standard methology of reporting. Correa and Yardley criticized the system for missing out certain types of the gastritis and well as it is not a ‘classification’ (Correa & Yardley, 1992). Consequently, a new system needed to gain wider acceptance.
In 1994, a two-day consensus meeting was held in Houston. After this another consensus report, “Up-dated Sydney System” was published in 1997 (Dixon et al, 1996). Original classification of gastritis dividing into acute, chronic and special forms, and grading of chronic inflammation, polymorph activity, atrophy, intestinal metaplasia and H. pylori density into mild, moderate and marked categories were kept. This up-dated system introduced a visual analogue scale for evaluating the severity of histopathological elements (grading). It changed the routine of endoscopic biopsy sampling by the introduction of biopsy sampling from the incisura angularis and modified corpus and antrum biopsy locations from the two opposite walls to lesser and greater curvature of both parts. The Up-dated Sydney Classification received different reactions among pathologists. Most of the pathologist agreed with the need of incisural biopsy, since the most degree of atrophy and intestinal metaplasia is found in the incisural region. That would reduce the sampling error of missing premalignant lesions and improve the diagnosis of multifocal gastritis. However, later prospective studies could not really show its benefit (Stolte & Meining, 2001). Even in our conducted study higher number of intestinal metaplasia were found in antral biopsies then in the biopsies taken from the incisura angularis (Szabo et al, 2012). After the development of the visual analogue scale according to the Up-dated Sydney System, the grading of atrophy still continued to show a considerable inter-observer variability (El-Zimaity et al, 1996). The updated system categorised chronic gastritis into ‘non-atrophic’ and ‘atrophic’ forms with the latter divided into autoimmune (diffuse corpus atrophy) and multifocal. Histological reporting of gastritis should take into account the topographical pattern (antral or corpus predominant), and the final diagnostic term should ideally combine morphology and etiology to maximize the clinical value of gastric biopsy diagnosis (Dixon et al, 1997). The up-dated system beside its major benefits in further standardizing endoscopic sampling, histological assessment and formality of reporting, still showed weaknesses specially in grading atrophy as pointed out by Johan A. Offerhaus in 1999 (see ref). His proposition was to simplify the grading system to two grades (low and high).
The clearest division of gastritis for clinicians was published by Appleman in 1994. He divided gastric inflammatory diseases to acute and chronic (see Table II). The most common form of gastritis that was called earlier as chronic diffuse antral gastritis, gastritis chronic type B, gastritis chronica active antralis, gastritis non-specifica or gastritis typus hypersecretions was named as Helicobacter pylori related gastritis. At this time lot of work proved that H. pylori infection causes chronic gastritis in the prepyloric region later leading to atrophy of glands and development of gastric adenocarcinoma and less frequently of lymphoma (Appelman, 1994, Kozlowski et al, 2011).
According to Appelman’s classification the autoimmune gastritis used to be called as gastritis autoimmunogenes, gastritis chronic atrophica typus A, gastritis chronic typus A and gastritis chronic diffusa corporis, was called to autoimmune chronic atrophic gastritis. Appelman pointed out the presence of autoantibodies against parietal cells and intrinsic factor being important in diagnosis, enterochromaffinlike (ECL) cell hyperplasia and risk of carcinoma.
Appelman’s classification of gastritis continues with the multifocal atrophic gastritis earlier called as environmental gastritis or type B chronic atrophic gastritis. At that time the cause of this form of gastritis was not clearly known. Beside known environmental factors responsible for geographic differences in its epidemiology, raising circumstantial evidences from an Italian study examining gastric distribution of H. pylori, pointed out the role of H. pylori in its generation (Rugge et al, 1993). Evidences suggested that H. pylori first infects the antrum, and later it involves the body leading to atrophic gastritis.
Appelman seeing similarity of the histological changes of patients with gastroenteric anastomosis and taking nonsteroidal anti-inflammatory (NSAID) medications, called third division of gastritis caused by bile reflux or NSAIDs to chemical gastropathies. Due to less inflammation these histological changes consisting foveolar hyperplasia, decrease of mucin in foveolar cells, superficial oedema, increase of smooth muscle fibres in the lamina propria were named as ‘gastropathies’. Recognition of this distinction of gastritis greatly helped to simply classification, although many times elements histological changes usually found in chemical gastropathy can be noticed in other forms of gastritis as well as in other gastric disease. Finding them singular and unassociated wit other changes like atrophy, intestinal metaplasia, presence of bacteria, ulcers, polyps, should raise the possibility of chemical gastritis.
Appelman kept the name of lymphotic gastritis used by his frontiers for the fourth distinctive form of gastritis (Haot et al, 1988, 1990). In this form of chronic gastritis huge lymphocytic infiltration of the surface epithelium, superficial pits and lamina propria can be observed. Others used to call this as superficial gastritis, gastritis chronic erosive or gastritis varioliformis. That time in 1990, the histological changes seen in lymphocytic gastritis was already described in patients with sprues and gluten-sensitivity. Lymphocytic gastritis tends to form “varioliform gastritis” endoscopically. This includes thick folds and small bumps with central depression seen during endoscopy. But lymphocytic gastritis also can form giant folds leading clinical symptoms (Ménétrier’s disease).
Appelman’s division of gastritis contained a miscellaneous group of gastritis. There are many gastritis forms that do not differ significantly from similar inflammations found other organs, including those that occur in syphilis, mycobacterial and cytomegalovirus, human immunodeficiency virus infections, histoplasmosis, candidiasis, cryptosporidiosis and other opportunistic fungi. There is a family of granulomatous reactions or granulomatous gastritis. Some of these are part of a systemic or focal gut granulomatous disease, such as sarcoidosis or Crohn’s disease, and some have been described as part of a systemic vasculitis syndrome or Whipple’s disease. There are still others which are not associated with any other diseases and designated as ‘isolated granulomatous gastritis’. Allergic gastritis is usually part of a gastrointestinal allergic disease. Appelman also categorized the recently described collagenous gastritis into this miscellaneous group.
\n\t\t\t\tAcute\n\t\t\t | \n\t\t\tAcute infectious gastritis (including Hp) | \n\t\t|
Erosive (caused mostly by NSAID or alcohol) | \n\t\t||
Necrotising and haemorrhagic (caused mostly by ischaemia) | \n\t\t||
\n\t\t\t\tChronic\n\t\t\t | \n\t\t\tHelicobacter pylori type | \n\t\t|
\n\t\t\t\tAtrophic\n\t\t\t | \n\t\t\tType A: autoimmune, diffuse | \n\t\t|
Type B: non-autoimmune, multifocal, enviromental | \n\t\t||
\n\t\t\t\tLymphocytic\n\t\t\t | \n\t\t\tIncluding varioliform, ’sprue-like’ and Ménétrier-like | \n\t\t|
\n\t\t\t\tChemical¤\n\t\t\t | \n\t\t\tBile reflux | \n\t\t|
NSAIDs | \n\t\t||
others (caused by other damaging agents and physical trauma) | \n\t\t||
\n\t\t\t\tMiscellaneous\n\t\t\t | \n\t\t\tGranulomatous (part of Crohn’s, Whipple’s, vasculitis, sarcoidosis or isolated granulomatous gastritis) | \n\t\t|
Allergic | \n\t\t||
Specific infectious (HIV, mycobacterial, syphilis, Cytomegalovirus, histoplasmosis, cryptosporidiosis | \n\t\t||
Collagenous | \n\t\t
Appleman’s classification of gastritis (1994)
◦ Gastropathies
Warren and Meissner describing intestinal metaplasia and recognising the clinical-pathological pattern of gastritis, described the bases of etiopathogenic relationship between gastric cancer and chronic gastritis (Warren & Meissner, 1944; Rugge et al, 2003). In 1980, Morson et al. (see ref.) defined gastric precancerous conditions as atrophic gastritis, gastric ulcer, pernicious anaemia, gastric stumps, gastric polyps, and Ménétrier\'s disease. They emphasized that epithelial dysplasia being a precancerous lesion is common in these conditions; dysplasia should be graded as mild, moderate and severe; and underlined the problems of differentiating inflammatory or regenerative changes from mild dysplasia, and intramucosal carcinoma from severe dysplasia (Morson et al, 1980). Japanese pathologists by studying serial sections of gastric mucosa obtained from gastric cancer patients described several border line lesions with histological and cytological changes. The premalignant significance of these was questioned for quite a long time; finally, the long-term follow-up studies closed this debate (Rugge et al, 1994, 1997). The high inter-observer inconsistency in histological assessment of premalignant lesions and new result supporting their neoplastic intraglandular nature obtained from genotyping studies highlighted the need of a broad consensus to re-define precancerous lesions uniformly. International group of pathologists met in Padova, Italy in April, 1998 on an international consensus conference. The conference reached an agreement on the definitions of the spectrum of gastric premalignant lesions and on common glossary for pathologist and clinicians, and applied strict diagnostic criteria (Rugge et al, 2000) (see Table III).
Negative for dysplasia | \n\t\t\t1.0 Normal | \n\t\t||
1.1 Reactive foveolar hyperplasia | \n\t\t|||
1.2 Intestinal metaplasia | \n\t\t\t1.2.1 Complete type | \n\t\t||
1.2.2 Incomplete type | \n\t\t|||
Indefinite for dysplasia | \n\t\t\t2.1 Foveolar hyperproliferation | \n\t\t||
2.2 Hyperproliferative intestinal metaplasia | \n\t\t|||
Non-invasive neoplasma (flat or elevated) | \n\t\t\t3.1 Low-grade | \n\t\t||
3.2 High-grade | \n\t\t\t3.2.1 Including suspicious for carcinoma without invasion (intraglandular) | \n\t\t||
3.2.2 Including carcinoma without invasion (intraglandular) | \n\t\t|||
Suspicious for invasive carcinoma | \n\t\t|||
Invasive carcinoma | \n\t\t
Padova Classification of gastric dysplasia and related lesions (2000)
The Sydney System and Up-dated Sydney System attempted to incorporate etiologic, topographic, and morphologic criteria into a clinically relevant scheme to reach a broad consensus in classification of gastritis. One of the most controversial issues at the Houston Workshop was the concept of atrophy. It was pointed out that "normal" was not precisely defined; the loss of appropriate glands occurs with distinct patterns and has different functional significance in antrum and corpus; the relationship between atrophy and intestinal metaplasia remained incompletely understood; and the topographic patterns of distribution and its evolution made the atrophic gastritis to the most controversial topic of gastritis (Genta, 1996). Later long-term follow-up studies have confirmed that the extent of gastric mucosal atrophy parallels gastric cancer risk (Meining et al, 2002; Sipponen et al, 1985, 1994, 1997; Stolte et al, 2000). At the same time Sydney System did not present a reporting terminology for chronic gastritis understandable and providing prognostic and therapeutic information for clinicians. Whereas, hepatitis staging had already improved useful, simple terminology for interdisciplinary communication representing disease progression and cancer risk.
Inspired by these facts, international group of gastroenterologists and pathologists named as Operative Link on Gastritis Assessment (OLGA) developed an improved histological staging system for gastric atrophy (Rugge & Genta, 2005a, 2005b). OLGA system uses the gastric biopsy sampling protocol defined by Sydney System and the visual analogue system recommended by the Up-dated Sydney System. The gastritis staging is defined from combined extent of atrophy scored histologically with the topography of atrophy identified through biopsy mapping (see Fig. 2). Long-term follow-up studies proved that gastritis OLGA staging conveys relevant information on clinic-pathological outcome of gastritis and therefore H. pylori negative patients with low OLGA stages could be confidently excluded from secondary preventive surveillance invasive procedures (Rugge et al, 2010). Whereas patients with high OLGA stages (Stages III and IV) should be considered definitely candidates for endoscopic surveillance. Significant correlation was shown between OLGA stages and pepsinogen serology (marker of gastric atrophy). The ratio of pepsinogen I and II gives adequate information on the severity of atrophy, but its measurement fails to differentiate between neoplastic and non-neoplastic disease among patients with high stages of gastric mucosal atrophy (Rugge et al, 2010).
Similar to the OLGA system another system, called the Baylor system was also introduced. The Baylor system follows the Baylor biopsy protocol (which uses Sydney System biopsy sites with two additional distal corporal biopsies) and scores the atrophy of antrum and corpus independently (Graham et al, 2006). Antral atrophy stage is an average score, but corpus atrophy stage is independent of antral atrophy, independent of individual reading in each biopsy but dependent on location. As corpus atrophy starts at the incisura and extends in continuity proximally and towards the greater curve, atrophy in a distal biopsy is early and atrophy in the most proximal location is advanced. The comparison of the two atrophy grading systems is still controversial. Although there were studies performed showing the superiority of Baylor system over OLGA in indentifying cancer risk (El-Zimaity et al, 2008), the evaluation of gastric atrophy by OLGA is more widely used, further developed and more studied.
Rugge et al. developed the OLGIM system for more precise evaluation of cancer risk. This system basically incorporates the OLGA frame, but replaces the atrophy score with an assessment of intestinal metaplasia (IM) alone. Examining a series of more than 4500 biopsies (2007-2009) showed that OLGIM staging is less sensitive than OLGA staging in the identification of patients at high risk of gastric cancer (Rugge et al, 2011). However, replacement of atrophic gastritis by intestinal metaplasia in the staging of gastritis considerably increases inter-observer agreement. The correlation with the severity of gastritis remains at least as strong. Therefore, the OLGIM may be preferred over the OLGA for the prediction of gastric cancer risk in patients with premalignant lesions (Capelle et al, 2010).
Gastritis Staging by OLGA system (Rugge & Genta, 2005a, 2005b, 2007), published in Gut in 2007. Atrophy is score in a four-tiered scale (0-3) in each compartment. The atrophy stage defined from the combination of atrophic changes assessed in gastric antral and corporal biopsies.
Even though above precursor lesions were commonly known and found in everyday practice, there were no international recommendation to guide the clinicians in management of patients with such lesions. This resulted wide heterogeneity of surveillance practice and failure in diagnosing patients with early, curable stage cancer. The European Society of Gastrointestinal Endoscopy (ESGE), the European Helicobacter Study Group (EHSG), the European Society of Pathology (ESP) and the Sociedade Portuguesa de Endoscopia Digestiva (SPED) have therefore combined efforts to develop evidence-based guideline on the management of patients with precancerous conditions and lesions in stomach (termed MAPS). Panel of European gastroenterologist pathologist and other researchers met in Barcelona, Spain in 2010, agreed on methodology, set up key questions for literature search and drafted preliminary statements. The panel divided into several subgroups searched for evidence on a certain question. Finally representatives of European national societies reviewed the evidence gathered and formed statements. Later, online sessions were held for voting and further comments; finally a second meeting held in Porto, Portugal finalized the guideline. The guideline details diagnostic assessment, treatment and follow-up of individuals with atrophic gastritis or intestinal metaplasia or dysplasia of gastric mucosa (Dinis-Ribeiro et al, 2012) (see Fig. 3).
Summary of management for patients with atrophic gastritis, gastric intestinal metaplasia and gastric epithelial dysplasia. Published in Endoscopy, 2012 (Dinis-Ribeiro et al, 2012).
The recommendations contain that conventional white light endoscopy cannot accurately differentiate between and diagnose pre-neoplastic gastric conditions/lesions. Thus, magnification chromoendoscopy or narrow-band imaging (NBI) endoscopy with or without magnification may be offered in these cases as it improves diagnosis of such lesions. In addition, at least four biopsies of the proximal and distal stomach, on the lesser and greater curvature, are needed for adequate assessment of premalignant gastric conditions. Systems for histopathological staging (e.g. OLGA or OLGIM assessment) may be useful for identifying subgroups of patients with different risks of progression to gastric cancer namely those with extensive lesions (i. e., atrophy and/or intestinal metaplasia in both antrum and corpus). Although only low potential applicability was reported by participants for this indicator, low serum pepsinogen levels can also predict this phenotype and, in such patients, H. pylori serology may also be useful for further detection of high risk individuals. Beyond a family history of gastric cancer, neither age, gender, H. pylori virulence factors, or host genetic variations change these clinical recommendations. Patients with extensive atrophy and/or extensive intestinal metaplasia should be offered endoscopic surveillance every 3 years. Patients with mild to moderate atrophy/intestinal metaplasia only in antrum do not need follow-up. If H. pylori infection is present, eradication should be offered to prevent high grade dysplasia or carcinoma. Patients with dysplasia without a visible endoscopic lesion should be closely followed up, either immediately and 6 to 12 months thereafter, or within 12 months, respectively, for those with high grade or low grade dysplasia. Those with dysplasia or cancer within an endoscopically visible lesion should undergo staging and resection (see Fig. 3.) (Dinis-Ribeiro et al, 2012).
This review critically offers and emphasizes the necessity of an international consensus meeting, which will establish a more uniform classification of gastritis respecting the wider multidisciplinary aspects (morphology, clinical picture, endoscopic view, immunology, bacteriology, molecular pharmacology, general medicine, oncology and causative factors as well as social/environmental circumstances of the people) in this field.
During the about last 150 years the knowledge on “gastritides” has enlarged enormously. The discovered new forms of gastritis, the new etiopathogenic evidences have continuously modified our views on gastritis classification. Recently, good agreement has been established among pathologist and clinicians to standardise the methodology of biopsy sampling, histological assessment and reporting leading to reproducible and clinically useful diagnosis. Recent recommendations for the management of bleeding, H. pylori infected or cancer risk patients help clinicians to endorse up-to-date therapy and follow-up. Presently there are still many unanswered questions regarding lot of segment of various forms of gastritis. Pathologist still need to issue descriptive histological report of ‘chronic non-specific gastritis’ to clinicians due to either lack of clinical information or knowledge of identifying gastric inflammations distinctive from known categories. For reducing the number of these cases further communication and consensus (as well as further consensus meetings) will be needed between pathologists and gastroenterologists. The growing information from research and clinical studies might show further new directions and require modification of classification. It is possible that at some day the presently known different types of gastritis will be known as various stages of the same disease, or partition of a present form could happen due to discovered futural diverse etiologic causes.
The majority of the world’s population works. Therefore, work plays an important role in their lives. For personal development and economic needs, it is the most important factor for people. However, working conditions and the way people approach their work life have a great impact on their quality of life and well-being. According to the literature review, workaholism is increasing rapidly compared to previous years, and thus, it seems that there is an increased interest in workaholism-related issues among researchers% [1, 2, 3]. In Norway, the recent study by Andreassen et al. [1] showed that the prevalence of workaholism was at 7.3%, but it may be that the rate of self-workaholism is much higher among the working population than it was estimated [2, 3]. Therefore, the amount of research associated with workaholism has been increasing in recent years, and the terms “work addiction”, “workaholism”, “excessively overwork” have been prevalent throughout [4, 5, 6, 7]. However, it seems that there is no common consensus about its meaning, which may very well be considered an important public issue in the future; this is because it gradually deteriorates people’s health, causing mental and physical health problems, such as coronary heart disease, anxiety, and work-related stress. For a long time now, it has also had a negative influence on people’s social lives, including family relationships and work performance—resulting in the decreasing of quality of life and well-being. Workaholics tend to spend most of their time working, leaving aside their social life, which leads to having more family conflicts and a lack of recreational activities [3, 4]. These results can be explained by the fact that they constantly feel stressed and pressured to succeed, physically harming themselves due to their work hours. Beyond that, it has been stated that workaholics are more likely to have obsessive–compulsive disorder, attention-deficit disorder, and hyperactivity disorder, showing that workaholism may be a sign of deeper psychological or emotional problems.
Although much is known about the consequences of workaholism, there is very little information about the source of workaholism [3, 4, 5].
Therefore, this review was aimed to examine definitions of “workaholism”, the factors affecting the occurrence of workaholism, and the consequences of workaholism.
It was aimed to examine a variety of approaches to define workaholism in related literature; it also seeks to define, and discuss its etiology, related factors, outcomes, prevention, and its treatment subsequently. The PubMed/Medline database was used for reviewing related studies published in English. “Workaholism”, “obsessive–compulsive behavior”, and “quality of health” were used as keywords. There were no restrictions in place regarding setting, study design, or timeline.
The term “workaholism” originally derived from the word “alcoholism”. It is seen as type of addiction, similar to gambling and sex. According to written literature, it was first coined and used in 1971 by Wayne E. Oates. It was initially described as “addiction to work, the compulsive and uncontrollable need to work incessantly”, asserting that workaholism is an addiction to work and has many common connections to alcoholism. At this time, workaholism was simply defined by Oates [3] as “a person whose need for work has become so excessive that it creates noticeable disturbance or interference with his bodily health, personal happiness, and interpersonal relationships, and with his smooth social functioning” [3]. However, compared to other common addictions, such as gambling or drug use, the definition of work addiction is still being developed through a variety of discussion, thought, or confusion [4, 5, 6]. In last half century, workaholism, as a term, has been widely used in related literature. For example, it was defined workaholism according to working hours per week. Nevertheless, this approach can easily meet resistance, particularly in developing and undeveloped countries where people commonly work more than what the definition states. At this point, some writers argue that simply focusing on the criteria of time is not enough to define people as “workaholics” [8]. Machlowitz defined “workaholism” as an approach or attitude toward working instead of explaining it with just the amount of time put in at work, since it is well known that “workaholics” keep thinking about work even when they are not there. A qualitative study was conducted with more than 100 workaholics, and the results showed that these workers were happy and satisfied with their life [9]. However, as it has been stated, there are a variety of different approaches for defining “workaholism”, with no consensus regarding the term. Some scientists present workaholism in positive terms and images by stressing the benefits from a high work investment, including extra work effort [9, 10], but others present it in negative terms and have emphasized the riskier sides, including health and “work-life conflicts” [3, 4, 5, 6, 7, 10, 11]. The writers who view workaholism negatively term interpreted “workaholism” as being equal to other addictions. Thus, they have focused on its detrimental effects. For example, Cherrington views workaholism as a preposterous dedication to extreme work [12]. On the other hand, some writers see “workaholism” as a decisive individual characteristic [13, 14, 15]. It is also possible, through the literature [16], to define “workaholism” using four distinguished aspects:
Robinson and Scott define workaholism behaviourally [13, 17], and Machlowitz, Spence, and Robinson define it attitudinally [9, 14].
Killinger, Oates, and Robinson view workaholism as an addiction [3, 18, 19].
It is acknowledged as having different types with various antecedents and outcomes [13, 14, 21, 22].
Spence and Robinson [14] define “workaholism” as a set of varied attitudes and behavioral patterns. The patterns consist of high levels of psychological involvement with work, intrinsic drive to work, and low or no work enjoyment (a high level of enjoyment describes an enthusiastic workaholic, and a low level of enjoyment describes a workaholic) [14]. According to them, the workaholic who is “highly work involved, feels compelled or driven to work because of inner pressures and is low in enjoyment of work”. Their definition of workaholism has been widely used and accepted in the literature. They have used “workaholic triad” as a measurement of workaholism. The triad consists of three dimensions: “work involvement”, “feeling driven to work”, and “work enjoyment”. They identify three types of workaholics based on the scores from the dimensions. The workaholic dimension types are “work addict”, “work enthusiast”, and “enthusiastic work addict”. For instance, the person in the “work enjoyment” category has a low work addiction score, but the “work involvement” and “feeling driven to work” dimensions have a high work addiction score. “Work enthusiasts” get a high work addiction score from the “work involvement” and “work enjoyment” dimensions, but they receive a low work addiction score from the “feeling driven to work” dimension [14]. However, “enthusiastic work addicts” get a high work addiction score from all three dimensions. They have also defined six sub-types of workaholics and non-workaholics, which are “work addicts”, “enthusiastic workaholics”, “work enthusiast”, “disenchanted workers”, “relaxed workers”, and “unengaged workers”. Each of them shows a different level of reaction based on the dimensions mentioned above [22] (see Table 1). Compared to other sub-types of the workaholics, “work addicts” are expected to be perfectionists, to experience higher levels of stress, and to complain more about physical health problems. Machlowitz has brought similar themes with her. She alleged that “what set workaholics apart is their attitude towards work, not the number of hours they work”. According to her, the definition relies on “physic income”, which is based on responsibility, sense, opportunity, and recognition (not monetary) [9]. Later, Buelens and Poelmans reiterate Spence and Robinson’s six-sub types of workaholics and developed it further, identifying the “reluctant hard worker” as an additional sub-type, while also speculating that “alienated professionals” might be an additional sub-type [21].
Workaholics’ sub-types | Dimension of workaholism | ||
---|---|---|---|
Feeling driven to work | Work enjoyment | Work involvement | |
Workaholic | High | Low | High |
Enthusiastic workaholic | High | High | High |
Work enthusiast | Low | High | High |
Relaxed worker | Low | High | Low |
Disgruntled worker | High | Low | Low |
Uninvolved worker | Low | Low | Low |
Dimension of workaholism and workaholics’ sub-types.
“Workaholism” is also defined as a person who spends an excessive amount time at work, resulting in a deterioration of family, social relationships, and recreational needs. It is argued that a workaholic has some specific characteristics, such as spending substantial unprompted time in work activities, thinking about the job when not at work, and working beyond organizational or economical requirements [14]. In their defense of the concept “Work beyond organizational or economical requirements”, they think that the organizational work pressure leads people to work more, but if this effort is beyond what is logically expected it should be considered workaholism. So, in the workaholic organization people are expected to “work hard”, but if the work expectation—based on the organization’s criteria—is not met, workers do not have many choices except leaving work or being dismissed. Thus, the result of the organizational requirement can vary. It depends on the workers, but if the workers have no choice other than accepting to meet the standards of the workaholic organization, they will be appropriately considered to be a workaholic. They stated that the workaholic may indicate one of the workaholism patterns, which have been classified by them [14]:
Compulsive-dependent workaholic: It is claimed that people who are compulsive-dependent workaholics will most likely have positive associations with the level of stress, anxiety, physical and psychological well-being, and health, but they will also have negative associations with job performance and job-life satisfaction. It can be interpreted that the more the worker is a compulsive-dependent workaholic the more the worker tends to have a poor quality of life.
Perfectionist workaholic: Generally, people who have an obsessive–compulsive disorder exhibit a perfectionist personality. So, perfectionists may be very likely to have problems in their relationships at work, with their families, and in their social lives. They hold a very high standards for themselves and for their goals; they are also success-oriented at work, and their levels of stress and anxiety are high. Shortly, perfectionists may have a low quality of life and well-being in long time. According to Scott et al., a “perfectionist workaholic” will correlate positively with the levels of physical and psychological health, stress, antagonistic interpersonal relationships, voluntary turnover and absenteeism, and low job performance and satisfaction. Naughton presents a focused approach with this pattern. He explains that “workaholism” is based on two dimensions: “obsession compulsion” and “career commitment” [23].
Achieve-oriented workaholic: It is a very likely possible to see obsessive–compulsive disorder in one’s health records. These workers relate positively to health problems, job and life satisfaction, job performance, low voluntary turnover, and pro-social behavior.
They claim that long working hours do not necessarily characterize workaholics. Douglas and Morris claim that “working long hours is a behavioural pattern, which is likely triggered by certain attitudes”. Additionally, there might be a variety of reasons for working long hours and maybe only some of them would be considered workaholism; for example, people who have a high work involvement and attitude are predisposed to work long hours and are, therefore, more inclined to suffer from workaholism [16].
Snir and Zohar define “workaholism” as an individual’s consistent and considerable designation of time to work-related activities and thoughts that are not derived from external necessities. According to them, there are some advantages to this definition over the others. For example, this definition is consistency, which means that workaholism should result from a temporary, heavy workload. Additionally, it also considers external necessities (e.g., working overtime to pay off debt or working long hours to advance one’s career), and focuses on values and attitudes [8]. It is based on the core elements of workaholism, discussed above. At this point, it is likely to see a common approach in some of the other writers’ definition of workaholism. For instance, they suggested that workaholics have three main characteristics: addiction, obsession, and driven to work due to internal needs, not external [3, 11, 18, 24]. Hakanen and Peters suggested a different approach to defining workaholism, comparing the typology of workaholics and engaged workers. They argued that workaholics are much more prone to invest their resources—such as attention, emotions, time, and energy—in work even if it hurts their social and private life. The workaholics will continue this behavioral pattern regardless of whether they fail or succeed. The workaholics’ behavior and mindset are on focused on work even when they are not at work [25]. When the “workaholism” definition is critiqued, described by variety of writers since 1971, “long working hours” is still a controversial component. In recent studies, the component has been discussed in detail. For example, the definition by Griffiths and Ng, along with the definition by Sorensen and Feldman, have developed a more contemporary definition, including a steady pattern of “high work investment”, “long working hours”, and working obsessively without organizational requirements [6, 26].
In the academic literature, the concept of long working hours generally reminds others of Japan, because the reason for working “long working hours” is simply the demand of employers or the desire of the workers—it is a part of a socio-cultural issue. For the Japanese, it is about fulfilling their duties to society, which they think they owe to themselves and their social being [27]. Recently, Robinson defined four types of workaholism: The blumic: “who makes it a point to do the job perfectly or not at all”; the relentless: “who are compulsively driven to work quickly and meet deadlines, and who find it difficult to stop working”; the savoring: “who are consumed by a preoccupation with details”; and the attention-deficit: “who start numerous projects/ventures but become easily dulled and restless, continually motivated to seek further challenges” [7]. In one of the recent definitions of workaholism, Wojdylo described it as a pathological work style and addiction disorder. Wojdylo has used the term “work craving” when defining workaholism. According to her, workaholism is comprised of a “obsessive–compulsive component”, “anticipation of self-worth compensatory incentives from work”, “anticipation of relief from negative affect or withdrawal symptoms resulting from working”, and “neurotic perfectionism” [28]. As it can be seen, “workaholism” typologies have been rarely discussed, based on theory or empirical studies.
There are a variety of factors that presumably induce and maintain workaholism. Some central theories and factors that may result in driven people falling into workaholism will be explained subsequently in the next paragraphs.
Workaholism may be associated with internal fundamental psychological needs for self-autonomy and competence. It is known that these fundamental internal needs have influence on developing people’s behavior [29]. Thus, workaholism might be correlated with these needs. For instance, when a person feels incompetent, that person will try hard to feel competent, which could be work-related, too. So, this obsession with work may be related to one’s unsatisfied needs. On the other hand, there are studies indicating that workaholism is also related to external behavior, such as the avoidance of criticism from people around them [30]. In this case, people hold high standards and ambitious work objectives, always trying to complete the best of their work, while avoiding their managers or co-workers to avoid any criticism. This approach and behavior may also relate to an obsessive–compulsive personality. Beyond that, it seems that there is a strong relationship between the personality and workaholism. Pitrowski and Vadanovich put forth that workaholism is developed from the integration of individual factors, such as personality traits and home and family characteristics; this includes roles, responsibilities, demanding internal and external factors (such as the appreciation of earning more money, either at home or at work, at first) [31]. Some studies explain the etiology of workaholism with personality traits such as “neuroticism”, “conscientiousness”, “narcissism”, and “perfectionism” [32, 33, 34, 35]. Furthermore, “obsessive-compulsion”, “achievement orientation”, “perfectionism”, and “conscientiousness” personality traits have a strong link to workaholism. “Perfectionism”, “preoccupation with orderliness”, “mental and interpersonal control”, “openness”, and “efficiency” are main characteristics of an obsessive–compulsive personality disorder [36]. A study concluded that “rigid perfectionism” is a core component of an obsessive–compulsive personality [37]. People who have an obsessive–compulsive personality chronically experience a variety of difficulties in their social and work lives. This type of personality may help lead people to becoming workaholics. In line with this, one study found that there were two aspects of an obsessive–compulsive personality that were prevalent in workaholism: feeling elevated levels of responsibility and being quietly stubborn [38]. Also, learned family values and intrinsic work values may relate to workaholism [26, 39]. Socio-cultural experiences, such as a stressful childhood and behavioral reinforcements that include tangible or intangible rewards, experiences of a “winner-takes-all system”, and an organizational environment can be precursor to workaholism [26]. “Joy in working”, “guilt and anxiety when not working”, “obsession with working”, and “working long hours” are defined as the immediate precursors to workaholism [40]. Additionally, some sociodemographic characteristics may lead to developing workaholism. For example, workaholism was found to be less likely among young blue-collar workers [41]; however, a study showed that there were no meaningful differences of workaholism found among gender, race, or age [42]. Beyond that, Beiler-May suggested that women, in reality, are more prone to workaholism than men [43]. Similar gender differences were found by other studies [14, 44]. Compared to men, women suffer from societal norms and restrictions, along with a higher responsibility for the (extra workload) [45]. Particularly, married women workers tend to have a second round of work at home by taking responsibility for the family and children. These barriers may prevent women from spending more time at work, therefore developing workaholism, as well [46, 47]. Nevertheless, it is claimed in other studies that men work relatively longer hours, which may cause them to be a workaholic [48].
Cognitive perspectives, psychological addiction models, and social and learning theories have also been used for explaining workaholism. According to the cognitive perspective, “basic cognitions”, such as supposition, expectancies, attributions, and automatic thoughts, are presumed to activate workaholic behavior [49]. Therefore, if a worker has a low-self-image and has a belief that working hard makes a person successful, the worker may then show workaholic behavior. Positive self-efficacy [50] might also be tied to the explanation of workaholism. If a worker thinks that he/she has a better positive efficacy at work more than outside (home or social life), he/she may prioritize work. Some studies tested cognitive perspective. For example, high self-efficacy was correlated with workaholism [44], driven in work was negatively regarded with self-esteem [49], and passive avoidance and depressive reactions were associated with an obsessive work drive [32]. In a study with administrative staff from a university, a cross-sectional structural model was examined. It concluded that enthusiastic workaholics high in self-efficacy showed high autonomy, mental competence, and emotional competence, but in turn it leads to subsequent workaholism [52].
Many scholars from the field of addiction obviously claim that workaholism is an addiction [16, 40, 53]. The medical addiction model explains the physical dependence on a substance. When the substance is absent, dependent people crave the substance and may show symptoms of withdrawal syndrome [43]. Thus, scholars from the addiction field claim that the concept of workaholism works with the concept of addiction [32].
The learning theory explains workaholism using normal learning principles [54]. According to the theory, if the conditions of workaholism are present, it can cause anyone to become a workaholic. The behavior of workaholics appears and is reinforced if the similar behaviors result in positive outcomes, such as praise from supervisors and a salary increase, or if it has led to negative outcomes, such as conflicts at home and bored with leisure time [7]. The social learning theory explains workaholic behavior: if a worker observes and sees the benefits in the behaviors of significant others (e.g., family members, managers, and leaders) leading to positive results, a workaholic’s behavior can be affected, mirroring them to reach desired outcomes.
Additionally, some researchers think that family perspective [55] and behavioral reinforcement, from an aetiological perspective [56], are prominent in developing workaholism. For example, family is central in an individual’s life, where one’s personality is built up and progressed. There are times when working long hours may equal that of caring for their family, which is seen as high in responsibility. Thus, this can possibly develop into workaholism. For example, in a student-led study, it was concluded that students who had a high workaholism score described their parents as hard-workers, and vice-versa for those who had a low workaholism score. On the other hand, behavioral reinforcements, such as organizational reward systems, satisfaction, complaints, and compliments, may lead to workaholism [24, 26, 56].
Workaholism has a variety of negative consequences. These are briefly related to work life, social and family life, and physical and psychological health. In the long-term, the influence of workaholism can negatively impact quality of life and well-being. In the following paragraphs, the overview of workaholism’s consequences will be discussed with reference to empirical studies.
Workaholics tend to have family problems. For example, workaholics experience a relatively high amount of work–family conflict [57, 58, 59], greater marital estrangement [60], feelings of being unsuccessful, being ineffective in solving family problems [2], rigid relationships with children and/or spouse [61], and children of workaholic parents have a higher level of psychological health problems, such as depression and external locus of control, compared to non-workaholic parents. It was reported that compared to men, female workaholics are relatively unlikely to get married [62].
Studies show that the negative life outcomes due to workaholism can be seen in all parts of life. These negative outcomes are perceived high stress [63, 64, 65, 66, 67], low self-esteem, low self-efficacy, low life-satisfaction, sleeping problems (e.g., insomnia or weak sleep) [64, 68, 69, 70], psychological distress [28], career dissatisfaction, poor job performance [51, 71], burnout [25, 72, 73], and higher amount of work–family conflict [74]. Additionally, a study conducted in Spain has supported the negative consequences discussed above. The study concluded that personality traits such as engagement, obsessive–compulsiveness, and life and life-style dissatisfaction were strong predictive factors of workaholism [75]. Furthermore, other negative consequences of workaholism include poor or worsening social functions [76], taking sick-leave [77], high blood pressure, cardiovascular risk [21, 78], obsessive–compulsive disorder, anxiety, depression [21, 79, 80], and physical pain [76, 80, 81, 82].
As a result, it appears that an internal obsessive work drive is a core element of workaholism correlated with many negative consequences. In addition, it has been found that workaholism is related to a decreasing psychological well-being, happiness in life, perceptions of health and happiness [52, 81], and self-reported work performance [81].
It seems that the occurrence of workaholism will be an increasing trend. Thus, first, it is crucial to take action to prevent workaholism. Second, effective treatment of workaholism should be applied, but related literature tends to be insufficient due to the lack of randomized and experiment-control designed studies. However, there are some prevention and treatment approaches that have been promoted in the related literature. In the following paragraphs, the approaches are given.
Prevention of workaholism among workers is an important issue. Regarding workaholism and its consequences, it could begin with increasing the awareness of academics, employers, workers, members of occupational health, and all other members of the community. Then, screening programs should be regularly applied at the workplace for diagnosing potential workaholics. Workaholics or potential workaholics should be under treatment and followed-up on regularly. Indeed, factors that are predisposed to workaholism should be found and adjusted as much as possible, especially since some factors are possibly not easily adjusted. Nevertheless, Sussman provides a systematic approach in the prevention of workaholism. He suggested that prevention of workaholism should comprise all extents of life, including levels of society, organization or organizational roles, and individual characteristics. Possible examples of effective prevention at the society level include providing the possibility of protecting and highlighting the importance of “work-family-personal life” balance, making employers close the workplace during national holidays in order to promote the need for recreation and personal interests, while using public service advertisements and virtual campaigns that combat workaholism. From the organizational level, an “Employee Assistance Program” can be used in the workplace. Workers should be encouraged to use vacation time, providing an opportunity for better engagement with the workplace and flexible roles in life [73, 83]. Periodic assessment can be applied at the workplace for examining workers’ happiness, job satisfaction, and needs, which can be used for addressing situations before they get worse. From the view of the individual, features that are predisposed to workaholism should be addressed and effective correction programs should be applied. For instance, one useful approach may be for employers to promote opportunities for recreation that restrict “work-family-personal” life overlap. Another important argument for preventing workaholism is the effects on children of workaholic parents. These children should be taught how to watch themselves for any indications of developing “workaholism”—being involved in group discussions might be helpful.
There are several treatment approaches that have been discussed in the related literature, summarized in a study by Andreassen [7]. Firstly, a clinical assessment should be completed for treating workaholism. After that, among treatment approaches used for workaholism, “Cognitive Behavioral Therapy” is well-documented and found to be effective for behavioral addictions [84]. It helps workaholics by setting limits; for instance, time-management principles can be used. A second treatment method is “Motivational Interviewing” [85]. The “Motivational Interviewing” program consists of ground principles— “show empathy, develop discrepancy, role with resistance, avoid argumentation and confrontation, support efficacy” —and communication skills— “open questions, affirmations, reflections and summations”, and strategies [7]. Another treatment method is “Positive psychology” [86]. This method focuses on strengths and positive human qualities rather than on inadequacy and negativity. The fourth and last treatment method is “Anonymous Workaholic”. It consists of a 12-step program. This method can be found worldwide on the internet, and people can benefit by attending online and offline meetings [87].
An overview of workaholism has been provided in this section. Despite a high prevalence of workaholism among the working population, not much is known about the issue. There is still not a consensus on its definition from the basis of science. The reasons people are driven into workaholism are relatively numerous and quite complex, including obsessive-compulsiveness, perfectionism, narcissism, sociocultural environment, and family and organizational characteristics (and so on). It appears that there is a great need for longitudinal and randomized control design studies for observing and examining the behaviors and health of workaholics.
There are no known direct or indirect potential competing interests relating to this work from any of the listed authors.
The study was not supported or funded by any company.
As an Open Access publisher, IntechOpen is dedicated to maintaining the highest ethical standards and principles in publishing. In addition, IntechOpen promotes the highest standards of integrity and ethical behavior in scientific research and peer-review. To maintain these principles IntechOpen has developed basic guidelines to facilitate the avoidance of Conflicts of Interest.
",metaTitle:"Conflicts of Interest Policy",metaDescription:"As an Open Access publisher, IntechOpen is dedicated to maintaining the highest ethical standards and principles in publishing. In addition, IntechOpen promotes the highest standards of integrity and ethical behavior in scientific research and peer-review.",metaKeywords:null,canonicalURL:"/page/conflicts-of-interest-policy",contentRaw:'[{"type":"htmlEditorComponent","content":"In each instance of a possible Conflict of Interest, IntechOpen aims to disclose the situation in as transparent a way as possible in order to allow readers to judge whether a particular potential Conflict of Interest has influenced the Work of any individual Author, Editor, or Reviewer. IntechOpen takes all possible Conflicts of Interest into account during the review process and ensures maximum transparency in implementing its policies.
\\n\\nA Conflict of Interest is a situation in which a person's professional judgment may be influenced by a range of factors, including financial gain, material interest, or some other personal or professional interest. For IntechOpen as a publisher, it is essential that all possible Conflicts of Interest are avoided. Each contributor, whether an Author, Editor, or Reviewer, who suspects they may have a Conflict of Interest, is obliged to declare that concern in order to make the publisher and the readership aware of any potential influence on the work being undertaken.
\\n\\nA Conflict of Interest can be identified at different phases of the publishing process.
\\n\\nIntechOpen requires:
\\n\\nCONFLICT OF INTEREST - AUTHOR
\\n\\nAll Authors are obliged to declare every existing or potential Conflict of Interest, including financial or personal factors, as well as any relationship which could influence their scientific work. Authors must declare Conflicts of Interest at the time of manuscript submission, although they may exceptionally do so at any point during manuscript review. For jointly prepared manuscripts, the corresponding Author is obliged to declare potential Conflicts of Interest of any other Authors who have contributed to the manuscript.
\\n\\nCONFLICT OF INTEREST – ACADEMIC EDITOR
\\n\\nEditors can also have Conflicts of Interest. Editors are expected to maintain the highest standards of conduct, which are outlined in our Best Practice Guidelines (templates for Best Practice Guidelines). Among other obligations, it is essential that Editors make transparent declarations of any possible Conflicts of Interest that they might have.
\\n\\nAvoidance Measures for Academic Editors of Conflicts of Interest:
\\n\\nFor manuscripts submitted by the Academic Editor (or a scientific advisor), an appropriate person will be appointed to handle and evaluate the manuscript. The appointed handling Editor's identity will not be disclosed to the Author in order to maintain impartiality and anonymity of the review.
\\n\\nIf a manuscript is submitted by an Author who is a member of an Academic Editor's family or is personally or professionally related to the Academic Editor in any way, either as a friend, colleague, student or mentor, the work will be handled by a different Academic Editor who is not in any way connected to the Author.
\\n\\nCONFLICT OF INTEREST - REVIEWER
\\n\\nAll Reviewers are required to declare possible Conflicts of Interest at the beginning of the evaluation process. If a Reviewer feels he or she might have any material, financial or any other conflict of interest with regards to the manuscript being reviewed, he or she is required to declare such concern and, if necessary, request exclusion from any further involvement in the evaluation process. A Reviewer's potential Conflicts of Interest are declared in the review report and presented to the Academic Editor, who then assesses whether or not the declared potential or actual Conflicts of Interest had, or could be perceived to have had, any significant impact on the review itself.
\\n\\nEXAMPLES OF CONFLICTS OF INTEREST:
\\n\\nFINANCIAL AND MATERIAL
\\n\\nNON-FINANCIAL
\\n\\nAuthors are required to declare all potentially relevant non-financial, financial and material Conflicts of Interest that may have had an influence on their scientific work.
\\n\\nAcademic Editors and Reviewers are required to declare any non-financial, financial and material Conflicts of Interest that could influence their fair and balanced evaluation of manuscripts. If such conflict exists with regards to a submitted manuscript, Academic Editors and Reviewers should exclude themselves from handling it.
\\n\\nAll Authors, Academic Editors, and Reviewers are required to declare all possible financial and material Conflicts of Interest in the last five years, although it is advisable to declare less recent Conflicts of Interest as well.
\\n\\nEXAMPLES:
\\n\\nAuthors should declare if they were or they still are Academic Editors of the publications in which they wish to publish their work.
\\n\\nAuthors should declare if they are board members of an organization that could benefit financially or materially from the publication of their work.
\\n\\nAcademic Editors should declare if they were coauthors or they have worked on the research project with the Author who has submitted a manuscript.
\\n\\nAcademic Editors should declare if the Author of a submitted manuscript is affiliated with the same department, faculty, institute, or company as they are.
\\n\\nPolicy last updated: 2016-06-09
\\n"}]'},components:[{type:"htmlEditorComponent",content:"In each instance of a possible Conflict of Interest, IntechOpen aims to disclose the situation in as transparent a way as possible in order to allow readers to judge whether a particular potential Conflict of Interest has influenced the Work of any individual Author, Editor, or Reviewer. IntechOpen takes all possible Conflicts of Interest into account during the review process and ensures maximum transparency in implementing its policies.
\n\nA Conflict of Interest is a situation in which a person's professional judgment may be influenced by a range of factors, including financial gain, material interest, or some other personal or professional interest. For IntechOpen as a publisher, it is essential that all possible Conflicts of Interest are avoided. Each contributor, whether an Author, Editor, or Reviewer, who suspects they may have a Conflict of Interest, is obliged to declare that concern in order to make the publisher and the readership aware of any potential influence on the work being undertaken.
\n\nA Conflict of Interest can be identified at different phases of the publishing process.
\n\nIntechOpen requires:
\n\nCONFLICT OF INTEREST - AUTHOR
\n\nAll Authors are obliged to declare every existing or potential Conflict of Interest, including financial or personal factors, as well as any relationship which could influence their scientific work. Authors must declare Conflicts of Interest at the time of manuscript submission, although they may exceptionally do so at any point during manuscript review. For jointly prepared manuscripts, the corresponding Author is obliged to declare potential Conflicts of Interest of any other Authors who have contributed to the manuscript.
\n\nCONFLICT OF INTEREST – ACADEMIC EDITOR
\n\nEditors can also have Conflicts of Interest. Editors are expected to maintain the highest standards of conduct, which are outlined in our Best Practice Guidelines (templates for Best Practice Guidelines). Among other obligations, it is essential that Editors make transparent declarations of any possible Conflicts of Interest that they might have.
\n\nAvoidance Measures for Academic Editors of Conflicts of Interest:
\n\nFor manuscripts submitted by the Academic Editor (or a scientific advisor), an appropriate person will be appointed to handle and evaluate the manuscript. The appointed handling Editor's identity will not be disclosed to the Author in order to maintain impartiality and anonymity of the review.
\n\nIf a manuscript is submitted by an Author who is a member of an Academic Editor's family or is personally or professionally related to the Academic Editor in any way, either as a friend, colleague, student or mentor, the work will be handled by a different Academic Editor who is not in any way connected to the Author.
\n\nCONFLICT OF INTEREST - REVIEWER
\n\nAll Reviewers are required to declare possible Conflicts of Interest at the beginning of the evaluation process. If a Reviewer feels he or she might have any material, financial or any other conflict of interest with regards to the manuscript being reviewed, he or she is required to declare such concern and, if necessary, request exclusion from any further involvement in the evaluation process. A Reviewer's potential Conflicts of Interest are declared in the review report and presented to the Academic Editor, who then assesses whether or not the declared potential or actual Conflicts of Interest had, or could be perceived to have had, any significant impact on the review itself.
\n\nEXAMPLES OF CONFLICTS OF INTEREST:
\n\nFINANCIAL AND MATERIAL
\n\nNON-FINANCIAL
\n\nAuthors are required to declare all potentially relevant non-financial, financial and material Conflicts of Interest that may have had an influence on their scientific work.
\n\nAcademic Editors and Reviewers are required to declare any non-financial, financial and material Conflicts of Interest that could influence their fair and balanced evaluation of manuscripts. If such conflict exists with regards to a submitted manuscript, Academic Editors and Reviewers should exclude themselves from handling it.
\n\nAll Authors, Academic Editors, and Reviewers are required to declare all possible financial and material Conflicts of Interest in the last five years, although it is advisable to declare less recent Conflicts of Interest as well.
\n\nEXAMPLES:
\n\nAuthors should declare if they were or they still are Academic Editors of the publications in which they wish to publish their work.
\n\nAuthors should declare if they are board members of an organization that could benefit financially or materially from the publication of their work.
\n\nAcademic Editors should declare if they were coauthors or they have worked on the research project with the Author who has submitted a manuscript.
\n\nAcademic Editors should declare if the Author of a submitted manuscript is affiliated with the same department, faculty, institute, or company as they are.
\n\nPolicy last updated: 2016-06-09
\n"}]},successStories:{items:[]},authorsAndEditors:{filterParams:{sort:"featured,name"},profiles:[{id:"105746",title:"Dr.",name:"A.W.M.M.",middleName:null,surname:"Koopman-van Gemert",slug:"a.w.m.m.-koopman-van-gemert",fullName:"A.W.M.M. Koopman-van Gemert",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/105746/images/5803_n.jpg",biography:"Dr. Anna Wilhelmina Margaretha Maria Koopman-van Gemert MD, PhD, became anaesthesiologist-intensivist from the Radboud University Nijmegen (the Netherlands) in 1987. She worked for a couple of years also as a blood bank director in Nijmegen and introduced in the Netherlands the Cell Saver and blood transfusion alternatives. She performed research in perioperative autotransfusion and obtained the degree of PhD in 1993 publishing Peri-operative autotransfusion by means of a blood cell separator.\nBlood transfusion had her special interest being the president of the Haemovigilance Chamber TRIP and performing several tasks in local and national blood bank and anticoagulant-blood transfusion guidelines committees. Currently, she is working as an associate professor and up till recently was the dean at the Albert Schweitzer Hospital Dordrecht. She performed (inter)national tasks as vice-president of the Concilium Anaesthesia and related committees. \nShe performed research in several fields, with over 100 publications in (inter)national journals and numerous papers on scientific conferences. \nShe received several awards and is a member of Honour of the Dutch Society of Anaesthesia.",institutionString:null,institution:{name:"Albert Schweitzer Hospital",country:{name:"Gabon"}}},{id:"83089",title:"Prof.",name:"Aaron",middleName:null,surname:"Ojule",slug:"aaron-ojule",fullName:"Aaron Ojule",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Port Harcourt",country:{name:"Nigeria"}}},{id:"295748",title:"Mr.",name:"Abayomi",middleName:null,surname:"Modupe",slug:"abayomi-modupe",fullName:"Abayomi Modupe",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/no_image.jpg",biography:null,institutionString:null,institution:{name:"Landmark University",country:{name:"Nigeria"}}},{id:"94191",title:"Prof.",name:"Abbas",middleName:null,surname:"Moustafa",slug:"abbas-moustafa",fullName:"Abbas Moustafa",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/94191/images/96_n.jpg",biography:"Prof. Moustafa got his doctoral degree in earthquake engineering and structural safety from Indian Institute of Science in 2002. He is currently an associate professor at Department of Civil Engineering, Minia University, Egypt and the chairman of Department of Civil Engineering, High Institute of Engineering and Technology, Giza, Egypt. He is also a consultant engineer and head of structural group at Hamza Associates, Giza, Egypt. Dr. Moustafa was a senior research associate at Vanderbilt University and a JSPS fellow at Kyoto and Nagasaki Universities. He has more than 40 research papers published in international journals and conferences. He acts as an editorial board member and a reviewer for several regional and international journals. His research interest includes earthquake engineering, seismic design, nonlinear dynamics, random vibration, structural reliability, structural health monitoring and uncertainty modeling.",institutionString:null,institution:{name:"Minia University",country:{name:"Egypt"}}},{id:"84562",title:"Dr.",name:"Abbyssinia",middleName:null,surname:"Mushunje",slug:"abbyssinia-mushunje",fullName:"Abbyssinia Mushunje",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"University of Fort Hare",country:{name:"South Africa"}}},{id:"202206",title:"Associate Prof.",name:"Abd Elmoniem",middleName:"Ahmed",surname:"Elzain",slug:"abd-elmoniem-elzain",fullName:"Abd Elmoniem Elzain",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Kassala University",country:{name:"Sudan"}}},{id:"98127",title:"Dr.",name:"Abdallah",middleName:null,surname:"Handoura",slug:"abdallah-handoura",fullName:"Abdallah Handoura",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"École Supérieure des Télécommunications",country:{name:"Morocco"}}},{id:"91404",title:"Prof.",name:"Abdecharif",middleName:null,surname:"Boumaza",slug:"abdecharif-boumaza",fullName:"Abdecharif Boumaza",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Abbès Laghrour University of Khenchela",country:{name:"Algeria"}}},{id:"105795",title:"Prof.",name:"Abdel Ghani",middleName:null,surname:"Aissaoui",slug:"abdel-ghani-aissaoui",fullName:"Abdel Ghani Aissaoui",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/105795/images/system/105795.jpeg",biography:"Abdel Ghani AISSAOUI is a Full Professor of electrical engineering at University of Bechar (ALGERIA). He was born in 1969 in Naama, Algeria. He received his BS degree in 1993, the MS degree in 1997, the PhD degree in 2007 from the Electrical Engineering Institute of Djilali Liabes University of Sidi Bel Abbes (ALGERIA). He is an active member of IRECOM (Interaction Réseaux Electriques - COnvertisseurs Machines) Laboratory and IEEE senior member. He is an editor member for many international journals (IJET, RSE, MER, IJECE, etc.), he serves as a reviewer in international journals (IJAC, ECPS, COMPEL, etc.). He serves as member in technical committee (TPC) and reviewer in international conferences (CHUSER 2011, SHUSER 2012, PECON 2012, SAI 2013, SCSE2013, SDM2014, SEB2014, PEMC2014, PEAM2014, SEB (2014, 2015), ICRERA (2015, 2016, 2017, 2018,-2019), etc.). His current research interest includes power electronics, control of electrical machines, artificial intelligence and Renewable energies.",institutionString:"University of Béchar",institution:{name:"University of Béchar",country:{name:"Algeria"}}},{id:"99749",title:"Dr.",name:"Abdel Hafid",middleName:null,surname:"Essadki",slug:"abdel-hafid-essadki",fullName:"Abdel Hafid Essadki",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"École Nationale Supérieure de Technologie",country:{name:"Algeria"}}},{id:"101208",title:"Prof.",name:"Abdel Karim",middleName:"Mohamad",surname:"El Hemaly",slug:"abdel-karim-el-hemaly",fullName:"Abdel Karim El Hemaly",position:null,profilePictureURL:"https://mts.intechopen.com/storage/users/101208/images/733_n.jpg",biography:"OBGYN.net Editorial Advisor Urogynecology.\nAbdel Karim M. A. El-Hemaly, MRCOG, FRCS � Egypt.\n \nAbdel Karim M. A. El-Hemaly\nProfessor OB/GYN & Urogynecology\nFaculty of medicine, Al-Azhar University \nPersonal Information: \nMarried with two children\nWife: Professor Laila A. Moussa MD.\nSons: Mohamad A. M. El-Hemaly Jr. MD. Died March 25-2007\nMostafa A. M. El-Hemaly, Computer Scientist working at Microsoft Seatle, USA. \nQualifications: \n1.\tM.B.-Bch Cairo Univ. June 1963. \n2.\tDiploma Ob./Gyn. Cairo Univ. April 1966. \n3.\tDiploma Surgery Cairo Univ. Oct. 1966. \n4.\tMRCOG London Feb. 1975. \n5.\tF.R.C.S. Glasgow June 1976. \n6.\tPopulation Study Johns Hopkins 1981. \n7.\tGyn. Oncology Johns Hopkins 1983. \n8.\tAdvanced Laparoscopic Surgery, with Prof. Paulson, Alexandria, Virginia USA 1993. \nSocieties & Associations: \n1.\t Member of the Royal College of Ob./Gyn. London. \n2.\tFellow of the Royal College of Surgeons Glasgow UK. \n3.\tMember of the advisory board on urogyn. FIGO. \n4.\tMember of the New York Academy of Sciences. \n5.\tMember of the American Association for the Advancement of Science. \n6.\tFeatured in �Who is Who in the World� from the 16th edition to the 20th edition. \n7.\tFeatured in �Who is Who in Science and Engineering� in the 7th edition. \n8.\tMember of the Egyptian Fertility & Sterility Society. \n9.\tMember of the Egyptian Society of Ob./Gyn. \n10.\tMember of the Egyptian Society of Urogyn. \n\nScientific Publications & Communications:\n1- Abdel Karim M. El Hemaly*, Ibrahim M. Kandil, Asim Kurjak, Ahmad G. Serour, Laila A. S. Mousa, Amr M. Zaied, Khalid Z. El Sheikha. \nImaging the Internal Urethral Sphincter and the Vagina in Normal Women and Women Suffering from Stress Urinary Incontinence and Vaginal Prolapse. Gynaecologia Et Perinatologia, Vol18, No 4; 169-286 October-December 2009.\n2- Abdel Karim M. El Hemaly*, Laila A. S. Mousa Ibrahim M. Kandil, Fatma S. El Sokkary, Ahmad G. Serour, Hossam Hussein.\nFecal Incontinence, A Novel Concept: The Role of the internal Anal sphincter (IAS) in defecation and fecal incontinence. Gynaecologia Et Perinatologia, Vol19, No 2; 79-85 April -June 2010.\n3- Abdel Karim M. El Hemaly*, Laila A. S. Mousa Ibrahim M. Kandil, Fatma S. El Sokkary, Ahmad G. Serour, Hossam Hussein.\nSurgical Treatment of Stress Urinary Incontinence, Fecal Incontinence and Vaginal Prolapse By A Novel Operation \n"Urethro-Ano-Vaginoplasty"\n Gynaecologia Et Perinatologia, Vol19, No 3; 129-188 July-September 2010.\n4- Abdel Karim M. El Hemaly*, Ibrahim M. Kandil, Laila A. S. Mousa and Mohamad A.K.M.El Hemaly.\nUrethro-vaginoplasty, an innovated operation for the treatment of: Stress Urinary Incontinence (SUI), Detursor Overactivity (DO), Mixed Urinary Incontinence and Anterior Vaginal Wall Descent. \nhttp://www.obgyn.net/urogyn/urogyn.asp?page=/urogyn/articles/ urethro-vaginoplasty_01\n\n5- Abdel Karim M. El Hemaly, Ibrahim M Kandil, Mohamed M. Radwan.\n Urethro-raphy a new technique for surgical management of Stress Urinary Incontinence.\nhttp://www.obgyn.net/urogyn/urogyn.asp?page=/urogyn/articles/\nnew-tech-urethro\n\n6- Abdel Karim M. El Hemaly, Ibrahim M Kandil, Mohamad A. Rizk, Nabil Abdel Maksoud H., Mohamad M. Radwan, Khalid Z. El Shieka, Mohamad A. K. M. El Hemaly, and Ahmad T. El Saban.\nUrethro-raphy The New Operation for the treatment of stress urinary incontinence, SUI, detrusor instability, DI, and mixed-type of urinary incontinence; short and long term results. \nhttp://www.obgyn.net/urogyn/urogyn.asp?page=urogyn/articles/\nurethroraphy-09280\n\n7-Abdel Karim M. El Hemaly, Ibrahim M Kandil, and Bahaa E. El Mohamady. Menopause, and Voiding troubles. \nhttp://www.obgyn.net/displayppt.asp?page=/English/pubs/features/presentations/El-Hemaly03/el-hemaly03-ss\n\n8-El Hemaly AKMA, Mousa L.A. Micturition and Urinary\tContinence. Int J Gynecol Obstet 1996; 42: 291-2. \n\n9-Abdel Karim M. El Hemaly.\n Urinary incontinence in gynecology, a review article.\nhttp://www.obgyn.net/urogyn/urogyn.asp?page=/urogyn/articles/abs-urinary_incotinence_gyn_ehemaly \n\n10-El Hemaly AKMA. Nocturnal Enuresis: Pathogenesis and Treatment. \nInt Urogynecol J Pelvic Floor Dysfunct 1998;9: 129-31.\n \n11-El Hemaly AKMA, Mousa L.A.E. Stress Urinary Incontinence, a New Concept. Eur J Obstet Gynecol Reprod Biol 1996; 68: 129-35. \n\n12- El Hemaly AKMA, Kandil I. M. Stress Urinary Incontinence SUI facts and fiction. Is SUI a puzzle?! http://www.obgyn.net/displayppt.asp?page=/English/pubs/features/presentations/El-Hemaly/el-hemaly-ss\n\n13-Abdel Karim El Hemaly, Nabil Abdel Maksoud, Laila A. Mousa, Ibrahim M. Kandil, Asem Anwar, M.A.K El Hemaly and Bahaa E. El Mohamady. \nEvidence based Facts on the Pathogenesis and Management of SUI. http://www.obgyn.net/displayppt.asp?page=/English/pubs/features/presentations/El-Hemaly02/el-hemaly02-ss\n\n14- Abdel Karim M. El Hemaly*, Ibrahim M. Kandil, Mohamad A. Rizk and Mohamad A.K.M.El Hemaly.\n Urethro-plasty, a Novel Operation based on a New Concept, for the Treatment of Stress Urinary Incontinence, S.U.I., Detrusor Instability, D.I., and Mixed-type of Urinary Incontinence.\nhttp://www.obgyn.net/urogyn/urogyn.asp?page=/urogyn/articles/urethro-plasty_01\n\n15-Ibrahim M. Kandil, Abdel Karim M. El Hemaly, Mohamad M. Radwan: Ultrasonic Assessment of the Internal Urethral Sphincter in Stress Urinary Incontinence. The Internet Journal of Gynecology and Obstetrics. 2003. Volume 2 Number 1. \n\n\n16-Abdel Karim M. El Hemaly. Nocturnal Enureses: A Novel Concept on its pathogenesis and Treatment.\nhttp://www.obgyn.net/urogynecolgy/?page=articles/nocturnal_enuresis\n\n17- Abdel Karim M. El Hemaly. Nocturnal Enureses: An Update on the pathogenesis and Treatment.\nhttp://www.obgyn.net/urogynecology/?page=/ENHLIDH/PUBD/FEATURES/\nPresentations/ Nocturnal_Enuresis/nocturnal_enuresis\n\n18-Maternal Mortality in Egypt, a cry for help and attention. The Second International Conference of the African Society of Organization & Gestosis, 1998, 3rd Annual International Conference of Ob/Gyn Department � Sohag Faculty of Medicine University. Feb. 11-13. Luxor, Egypt. \n19-Postmenopausal Osteprosis. The 2nd annual conference of Health Insurance Organization on Family Planning and its role in primary health care. Zagaziz, Egypt, February 26-27, 1997, Center of Complementary Services for Maternity and childhood care. \n20-Laparoscopic Assisted vaginal hysterectomy. 10th International Annual Congress Modern Trends in Reproductive Techniques 23-24 March 1995. Alexandria, Egypt. \n21-Immunological Studies in Pre-eclamptic Toxaemia. Proceedings of 10th Annual Ain Shams Medical Congress. Cairo, Egypt, March 6-10, 1987. \n22-Socio-demographic factorse affecting acceptability of the long-acting contraceptive injections in a rural Egyptian community. Journal of Biosocial Science 29:305, 1987. \n23-Plasma fibronectin levels hypertension during pregnancy. The Journal of the Egypt. Soc. of Ob./Gyn. 13:1, 17-21, Jan. 1987. \n24-Effect of smoking on pregnancy. Journal of Egypt. Soc. of Ob./Gyn. 12:3, 111-121, Sept 1986. \n25-Socio-demographic aspects of nausea and vomiting in early pregnancy. Journal of the Egypt. Soc. of Ob./Gyn. 12:3, 35-42, Sept. 1986. \n26-Effect of intrapartum oxygen inhalation on maternofetal blood gases and pH. Journal of the Egypt. Soc. of Ob./Gyn. 12:3, 57-64, Sept. 1986. \n27-The effect of severe pre-eclampsia on serum transaminases. The Egypt. J. Med. Sci. 7(2): 479-485, 1986. \n28-A study of placental immunoreceptors in pre-eclampsia. The Egypt. J. Med. Sci. 7(2): 211-216, 1986. \n29-Serum human placental lactogen (hpl) in normal, toxaemic and diabetic pregnant women, during pregnancy and its relation to the outcome of pregnancy. Journal of the Egypt. Soc. of Ob./Gyn. 12:2, 11-23, May 1986. \n30-Pregnancy specific B1 Glycoprotein and free estriol in the serum of normal, toxaemic and diabetic pregnant women during pregnancy and after delivery. Journal of the Egypt. Soc. of Ob./Gyn. 12:1, 63-70, Jan. 1986. Also was accepted and presented at Xith World Congress of Gynecology and Obstetrics, Berlin (West), September 15-20, 1985. \n31-Pregnancy and labor in women over the age of forty years. Accepted and presented at Al-Azhar International Medical Conference, Cairo 28-31 Dec. 1985. \n32-Effect of Copper T intra-uterine device on cervico-vaginal flora. Int. J. Gynaecol. Obstet. 23:2, 153-156, April 1985. \n33-Factors affecting the occurrence of post-Caesarean section febrile morbidity. Population Sciences, 6, 139-149, 1985. \n34-Pre-eclamptic toxaemia and its relation to H.L.A. system. Population Sciences, 6, 131-139, 1985. \n35-The menstrual pattern and occurrence of pregnancy one year after discontinuation of Depo-medroxy progesterone acetate as a postpartum contraceptive. Population Sciences, 6, 105-111, 1985. \n36-The menstrual pattern and side effects of Depo-medroxy progesterone acetate as postpartum contraceptive. Population Sciences, 6, 97-105, 1985. \n37-Actinomyces in the vaginas of women with and without intrauterine contraceptive devices. Population Sciences, 6, 77-85, 1985. \n38-Comparative efficacy of ibuprofen and etamsylate in the treatment of I.U.D. menorrhagia. Population Sciences, 6, 63-77, 1985. \n39-Changes in cervical mucus copper and zinc in women using I.U.D.�s. Population Sciences, 6, 35-41, 1985. \n40-Histochemical study of the endometrium of infertile women. Egypt. J. Histol. 8(1) 63-66, 1985. \n41-Genital flora in pre- and post-menopausal women. Egypt. J. Med. Sci. 4(2), 165-172, 1983. \n42-Evaluation of the vaginal rugae and thickness in 8 different groups. Journal of the Egypt. Soc. of Ob./Gyn. 9:2, 101-114, May 1983. \n43-The effect of menopausal status and conjugated oestrogen therapy on serum cholesterol, triglycerides and electrophoretic lipoprotein patterns. Al-Azhar Medical Journal, 12:2, 113-119, April 1983. \n44-Laparoscopic ventrosuspension: A New Technique. Int. J. Gynaecol. Obstet., 20, 129-31, 1982. \n45-The laparoscope: A useful diagnostic tool in general surgery. Al-Azhar Medical Journal, 11:4, 397-401, Oct. 1982. \n46-The value of the laparoscope in the diagnosis of polycystic ovary. Al-Azhar Medical Journal, 11:2, 153-159, April 1982. \n47-An anaesthetic approach to the management of eclampsia. Ain Shams Medical Journal, accepted for publication 1981. \n48-Laparoscopy on patients with previous lower abdominal surgery. Fertility management edited by E. Osman and M. Wahba 1981. \n49-Heart diseases with pregnancy. Population Sciences, 11, 121-130, 1981. \n50-A study of the biosocial factors affecting perinatal mortality in an Egyptian maternity hospital. Population Sciences, 6, 71-90, 1981. \n51-Pregnancy Wastage. Journal of the Egypt. Soc. of Ob./Gyn. 11:3, 57-67, Sept. 1980. \n52-Analysis of maternal deaths in Egyptian maternity hospitals. Population Sciences, 1, 59-65, 1979. \nArticles published on OBGYN.net: \n1- Abdel Karim M. El Hemaly*, Ibrahim M. Kandil, Laila A. S. Mousa and Mohamad A.K.M.El Hemaly.\nUrethro-vaginoplasty, an innovated operation for the treatment of: Stress Urinary Incontinence (SUI), Detursor Overactivity (DO), Mixed Urinary Incontinence and Anterior Vaginal Wall Descent. \nhttp://www.obgyn.net/urogyn/urogyn.asp?page=/urogyn/articles/ urethro-vaginoplasty_01\n\n2- Abdel Karim M. El Hemaly, Ibrahim M Kandil, Mohamed M. Radwan.\n Urethro-raphy a new technique for surgical management of Stress Urinary Incontinence.\nhttp://www.obgyn.net/urogyn/urogyn.asp?page=/urogyn/articles/\nnew-tech-urethro\n\n3- Abdel Karim M. El Hemaly, Ibrahim M Kandil, Mohamad A. Rizk, Nabil Abdel Maksoud H., Mohamad M. Radwan, Khalid Z. El Shieka, Mohamad A. K. M. El Hemaly, and Ahmad T. El Saban.\nUrethro-raphy The New Operation for the treatment of stress urinary incontinence, SUI, detrusor instability, DI, and mixed-type of urinary incontinence; short and long term results. \nhttp://www.obgyn.net/urogyn/urogyn.asp?page=urogyn/articles/\nurethroraphy-09280\n\n4-Abdel Karim M. El Hemaly, Ibrahim M Kandil, and Bahaa E. El Mohamady. Menopause, and Voiding troubles. \nhttp://www.obgyn.net/displayppt.asp?page=/English/pubs/features/presentations/El-Hemaly03/el-hemaly03-ss\n\n5-El Hemaly AKMA, Mousa L.A. Micturition and Urinary\tContinence. Int J Gynecol Obstet 1996; 42: 291-2. \n\n6-Abdel Karim M. El Hemaly.\n Urinary incontinence in gynecology, a review article.\nhttp://www.obgyn.net/urogyn/urogyn.asp?page=/urogyn/articles/abs-urinary_incotinence_gyn_ehemaly \n\n7-El Hemaly AKMA. Nocturnal Enuresis: Pathogenesis and Treatment. \nInt Urogynecol J Pelvic Floor Dysfunct 1998;9: 129-31.\n \n8-El Hemaly AKMA, Mousa L.A.E. Stress Urinary Incontinence, a New Concept. Eur J Obstet Gynecol Reprod Biol 1996; 68: 129-35. \n\n9- El Hemaly AKMA, Kandil I. M. Stress Urinary Incontinence SUI facts and fiction. Is SUI a puzzle?! http://www.obgyn.net/displayppt.asp?page=/English/pubs/features/presentations/El-Hemaly/el-hemaly-ss\n\n10-Abdel Karim El Hemaly, Nabil Abdel Maksoud, Laila A. Mousa, Ibrahim M. Kandil, Asem Anwar, M.A.K El Hemaly and Bahaa E. El Mohamady. \nEvidence based Facts on the Pathogenesis and Management of SUI. http://www.obgyn.net/displayppt.asp?page=/English/pubs/features/presentations/El-Hemaly02/el-hemaly02-ss\n\n11- Abdel Karim M. El Hemaly*, Ibrahim M. Kandil, Mohamad A. Rizk and Mohamad A.K.M.El Hemaly.\n Urethro-plasty, a Novel Operation based on a New Concept, for the Treatment of Stress Urinary Incontinence, S.U.I., Detrusor Instability, D.I., and Mixed-type of Urinary Incontinence.\nhttp://www.obgyn.net/urogyn/urogyn.asp?page=/urogyn/articles/urethro-plasty_01\n\n12-Ibrahim M. Kandil, Abdel Karim M. El Hemaly, Mohamad M. Radwan: Ultrasonic Assessment of the Internal Urethral Sphincter in Stress Urinary Incontinence. The Internet Journal of Gynecology and Obstetrics. 2003. Volume 2 Number 1. \n\n13-Abdel Karim M. El Hemaly. Nocturnal Enureses: A Novel Concept on its pathogenesis and Treatment.\nhttp://www.obgyn.net/urogynecolgy/?page=articles/nocturnal_enuresis\n\n14- Abdel Karim M. El Hemaly. Nocturnal Enureses: An Update on the pathogenesis and Treatment.\nhttp://www.obgyn.net/urogynecology/?page=/ENHLIDH/PUBD/FEATURES/\nPresentations/ Nocturnal_Enuresis/nocturnal_enuresis",institutionString:null,institution:{name:"Al Azhar University",country:{name:"Egypt"}}},{id:"113313",title:"Dr.",name:"Abdel-Aal",middleName:null,surname:"Mantawy",slug:"abdel-aal-mantawy",fullName:"Abdel-Aal Mantawy",position:null,profilePictureURL:"//cdnintech.com/web/frontend/www/assets/author.svg",biography:null,institutionString:null,institution:{name:"Ain Shams University",country:{name:"Egypt"}}}],filtersByRegion:[{group:"region",caption:"North America",value:1,count:5681},{group:"region",caption:"Middle and South America",value:2,count:5161},{group:"region",caption:"Africa",value:3,count:1683},{group:"region",caption:"Asia",value:4,count:10200},{group:"region",caption:"Australia and Oceania",value:5,count:886},{group:"region",caption:"Europe",value:6,count:15610}],offset:12,limit:12,total:1683},chapterEmbeded:{data:{}},editorApplication:{success:null,errors:{}},ofsBooks:{filterParams:{hasNoEditors:"1",sort:"dateEndThirdStepPublish",topicId:"6,13,16"},books:[{type:"book",id:"10231",title:"Proton Therapy",subtitle:null,isOpenForSubmission:!0,hash:"f4a9009287953c8d1d89f0fa9b7597b0",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10231.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10707",title:"Primary Care",subtitle:null,isOpenForSubmission:!0,hash:"bdb1aeb61b1eb116c1bdb09d25593686",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10707.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10715",title:"Brain MRI",subtitle:null,isOpenForSubmission:!0,hash:"6d56c88c53776966959f41f8b75daafd",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10715.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10723",title:"Brachial Plexus Injury",subtitle:null,isOpenForSubmission:!0,hash:"441fb315d751efcdc4ae3fdb03808b46",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10723.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10731",title:"Cannabinoids",subtitle:null,isOpenForSubmission:!0,hash:"1d2e090ecf2415b8d3c9fba15856b7b1",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10731.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10747",title:"Parvoviridae",subtitle:null,isOpenForSubmission:!0,hash:"694a3c1bc3af4d00d994fc83b527eacc",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10747.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10712",title:"Thrombectomy",subtitle:null,isOpenForSubmission:!0,hash:"853e71d74c3dd5007277d3770e639d47",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10712.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10721",title:"Preeclampsia",subtitle:null,isOpenForSubmission:!0,hash:"d23fca4321fbc65c3e5c3e0d377c6e1f",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10721.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10729",title:"Sepsis",subtitle:null,isOpenForSubmission:!0,hash:"3981e82a4ab305272c07784a8f7298fb",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10729.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10745",title:"Nematodes",subtitle:null,isOpenForSubmission:!0,hash:"3b04a8befc32e564599c44178d8a8152",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10745.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10708",title:"Regional Anesthesia",subtitle:null,isOpenForSubmission:!0,hash:"b481b3c45dfcce8c4f048ce08f520763",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10708.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10717",title:"Gestational Diabetes",subtitle:null,isOpenForSubmission:!0,hash:"9e38724c0e4f2bd852444e9b6f0facc8",slug:null,bookSignature:"",coverURL:"https://cdn.intechopen.com/books/images_new/10717.jpg",editedByType:null,editors:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],filtersByTopic:[{group:"topic",caption:"Agricultural and Biological Sciences",value:5,count:16},{group:"topic",caption:"Biochemistry, Genetics and Molecular Biology",value:6,count:9},{group:"topic",caption:"Business, Management and Economics",value:7,count:8},{group:"topic",caption:"Chemistry",value:8,count:4},{group:"topic",caption:"Computer and Information Science",value:9,count:9},{group:"topic",caption:"Earth and Planetary Sciences",value:10,count:7},{group:"topic",caption:"Engineering",value:11,count:13},{group:"topic",caption:"Environmental Sciences",value:12,count:6},{group:"topic",caption:"Immunology and Microbiology",value:13,count:7},{group:"topic",caption:"Materials Science",value:14,count:2},{group:"topic",caption:"Mathematics",value:15,count:2},{group:"topic",caption:"Medicine",value:16,count:45},{group:"topic",caption:"Nanotechnology and Nanomaterials",value:17,count:1},{group:"topic",caption:"Neuroscience",value:18,count:3},{group:"topic",caption:"Pharmacology, Toxicology and Pharmaceutical Science",value:19,count:3},{group:"topic",caption:"Physics",value:20,count:2},{group:"topic",caption:"Psychology",value:21,count:3},{group:"topic",caption:"Robotics",value:22,count:4},{group:"topic",caption:"Social Sciences",value:23,count:6},{group:"topic",caption:"Veterinary Medicine and Science",value:25,count:1}],offset:12,limit:12,total:61},popularBooks:{featuredBooks:[{type:"book",id:"9208",title:"Welding",subtitle:"Modern Topics",isOpenForSubmission:!1,hash:"7d6be076ccf3a3f8bd2ca52d86d4506b",slug:"welding-modern-topics",bookSignature:"Sadek Crisóstomo Absi Alfaro, Wojciech Borek and Błażej Tomiczek",coverURL:"https://cdn.intechopen.com/books/images_new/9208.jpg",editors:[{id:"65292",title:"Prof.",name:"Sadek Crisostomo Absi",middleName:"C. Absi",surname:"Alfaro",slug:"sadek-crisostomo-absi-alfaro",fullName:"Sadek Crisostomo Absi Alfaro"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9139",title:"Topics in Primary Care Medicine",subtitle:null,isOpenForSubmission:!1,hash:"ea774a4d4c1179da92a782e0ae9cde92",slug:"topics-in-primary-care-medicine",bookSignature:"Thomas F. Heston",coverURL:"https://cdn.intechopen.com/books/images_new/9139.jpg",editors:[{id:"217926",title:"Dr.",name:"Thomas F.",middleName:null,surname:"Heston",slug:"thomas-f.-heston",fullName:"Thomas F. Heston"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"8697",title:"Virtual Reality and Its Application in Education",subtitle:null,isOpenForSubmission:!1,hash:"ee01b5e387ba0062c6b0d1e9227bda05",slug:"virtual-reality-and-its-application-in-education",bookSignature:"Dragan Cvetković",coverURL:"https://cdn.intechopen.com/books/images_new/8697.jpg",editors:[{id:"101330",title:"Dr.",name:"Dragan",middleName:"Mladen",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9785",title:"Endometriosis",subtitle:null,isOpenForSubmission:!1,hash:"f457ca61f29cf7e8bc191732c50bb0ce",slug:"endometriosis",bookSignature:"Courtney Marsh",coverURL:"https://cdn.intechopen.com/books/images_new/9785.jpg",editors:[{id:"255491",title:"Dr.",name:"Courtney",middleName:null,surname:"Marsh",slug:"courtney-marsh",fullName:"Courtney Marsh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9343",title:"Trace Metals in the Environment",subtitle:"New Approaches and Recent Advances",isOpenForSubmission:!1,hash:"ae07e345bc2ce1ebbda9f70c5cd12141",slug:"trace-metals-in-the-environment-new-approaches-and-recent-advances",bookSignature:"Mario Alfonso Murillo-Tovar, Hugo Saldarriaga-Noreña and Agnieszka Saeid",coverURL:"https://cdn.intechopen.com/books/images_new/9343.jpg",editors:[{id:"255959",title:"Dr.",name:"Mario Alfonso",middleName:null,surname:"Murillo-Tovar",slug:"mario-alfonso-murillo-tovar",fullName:"Mario Alfonso Murillo-Tovar"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"7831",title:"Sustainability in Urban Planning and Design",subtitle:null,isOpenForSubmission:!1,hash:"c924420492c8c2c9751e178d025f4066",slug:"sustainability-in-urban-planning-and-design",bookSignature:"Amjad Almusaed, Asaad Almssad and Linh Truong - Hong",coverURL:"https://cdn.intechopen.com/books/images_new/7831.jpg",editors:[{id:"110471",title:"Dr.",name:"Amjad",middleName:"Zaki",surname:"Almusaed",slug:"amjad-almusaed",fullName:"Amjad Almusaed"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"8468",title:"Sheep Farming",subtitle:"An Approach to Feed, Growth and Sanity",isOpenForSubmission:!1,hash:"838f08594850bc04aa14ec873ed1b96f",slug:"sheep-farming-an-approach-to-feed-growth-and-sanity",bookSignature:"António Monteiro",coverURL:"https://cdn.intechopen.com/books/images_new/8468.jpg",editors:[{id:"190314",title:"Prof.",name:"António",middleName:"Cardoso",surname:"Monteiro",slug:"antonio-monteiro",fullName:"António Monteiro"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"8816",title:"Financial Crises",subtitle:"A Selection of Readings",isOpenForSubmission:!1,hash:"6f2f49fb903656e4e54280c79fabd10c",slug:"financial-crises-a-selection-of-readings",bookSignature:"Stelios Markoulis",coverURL:"https://cdn.intechopen.com/books/images_new/8816.jpg",editors:[{id:"237863",title:"Dr.",name:"Stelios",middleName:null,surname:"Markoulis",slug:"stelios-markoulis",fullName:"Stelios Markoulis"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9376",title:"Contemporary Developments and Perspectives in International Health Security",subtitle:"Volume 1",isOpenForSubmission:!1,hash:"b9a00b84cd04aae458fb1d6c65795601",slug:"contemporary-developments-and-perspectives-in-international-health-security-volume-1",bookSignature:"Stanislaw P. Stawicki, Michael S. Firstenberg, Sagar C. Galwankar, Ricardo Izurieta and Thomas Papadimos",coverURL:"https://cdn.intechopen.com/books/images_new/9376.jpg",editors:[{id:"181694",title:"Dr.",name:"Stanislaw P.",middleName:null,surname:"Stawicki",slug:"stanislaw-p.-stawicki",fullName:"Stanislaw P. Stawicki"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"7769",title:"Medical Isotopes",subtitle:null,isOpenForSubmission:!1,hash:"f8d3c5a6c9a42398e56b4e82264753f7",slug:"medical-isotopes",bookSignature:"Syed Ali Raza Naqvi and Muhammad Babar Imrani",coverURL:"https://cdn.intechopen.com/books/images_new/7769.jpg",editors:[{id:"259190",title:"Dr.",name:"Syed Ali Raza",middleName:null,surname:"Naqvi",slug:"syed-ali-raza-naqvi",fullName:"Syed Ali Raza Naqvi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9279",title:"Concepts, Applications and Emerging Opportunities in Industrial Engineering",subtitle:null,isOpenForSubmission:!1,hash:"9bfa87f9b627a5468b7c1e30b0eea07a",slug:"concepts-applications-and-emerging-opportunities-in-industrial-engineering",bookSignature:"Gary Moynihan",coverURL:"https://cdn.intechopen.com/books/images_new/9279.jpg",editors:[{id:"16974",title:"Dr.",name:"Gary",middleName:null,surname:"Moynihan",slug:"gary-moynihan",fullName:"Gary Moynihan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"7807",title:"A Closer Look at Organizational Culture in Action",subtitle:null,isOpenForSubmission:!1,hash:"05c608b9271cc2bc711f4b28748b247b",slug:"a-closer-look-at-organizational-culture-in-action",bookSignature:"Süleyman Davut Göker",coverURL:"https://cdn.intechopen.com/books/images_new/7807.jpg",editors:[{id:"190035",title:"Associate Prof.",name:"Süleyman Davut",middleName:null,surname:"Göker",slug:"suleyman-davut-goker",fullName:"Süleyman Davut Göker"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],offset:12,limit:12,total:5126},hotBookTopics:{hotBooks:[],offset:0,limit:12,total:null},publish:{},publishingProposal:{success:null,errors:{}},books:{featuredBooks:[{type:"book",id:"9208",title:"Welding",subtitle:"Modern Topics",isOpenForSubmission:!1,hash:"7d6be076ccf3a3f8bd2ca52d86d4506b",slug:"welding-modern-topics",bookSignature:"Sadek Crisóstomo Absi Alfaro, Wojciech Borek and Błażej Tomiczek",coverURL:"https://cdn.intechopen.com/books/images_new/9208.jpg",editors:[{id:"65292",title:"Prof.",name:"Sadek Crisostomo Absi",middleName:"C. Absi",surname:"Alfaro",slug:"sadek-crisostomo-absi-alfaro",fullName:"Sadek Crisostomo Absi Alfaro"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9139",title:"Topics in Primary Care Medicine",subtitle:null,isOpenForSubmission:!1,hash:"ea774a4d4c1179da92a782e0ae9cde92",slug:"topics-in-primary-care-medicine",bookSignature:"Thomas F. Heston",coverURL:"https://cdn.intechopen.com/books/images_new/9139.jpg",editors:[{id:"217926",title:"Dr.",name:"Thomas F.",middleName:null,surname:"Heston",slug:"thomas-f.-heston",fullName:"Thomas F. Heston"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"8697",title:"Virtual Reality and Its Application in Education",subtitle:null,isOpenForSubmission:!1,hash:"ee01b5e387ba0062c6b0d1e9227bda05",slug:"virtual-reality-and-its-application-in-education",bookSignature:"Dragan Cvetković",coverURL:"https://cdn.intechopen.com/books/images_new/8697.jpg",editors:[{id:"101330",title:"Dr.",name:"Dragan",middleName:"Mladen",surname:"Cvetković",slug:"dragan-cvetkovic",fullName:"Dragan Cvetković"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9785",title:"Endometriosis",subtitle:null,isOpenForSubmission:!1,hash:"f457ca61f29cf7e8bc191732c50bb0ce",slug:"endometriosis",bookSignature:"Courtney Marsh",coverURL:"https://cdn.intechopen.com/books/images_new/9785.jpg",editors:[{id:"255491",title:"Dr.",name:"Courtney",middleName:null,surname:"Marsh",slug:"courtney-marsh",fullName:"Courtney Marsh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9343",title:"Trace Metals in the Environment",subtitle:"New Approaches and Recent Advances",isOpenForSubmission:!1,hash:"ae07e345bc2ce1ebbda9f70c5cd12141",slug:"trace-metals-in-the-environment-new-approaches-and-recent-advances",bookSignature:"Mario Alfonso Murillo-Tovar, Hugo Saldarriaga-Noreña and Agnieszka Saeid",coverURL:"https://cdn.intechopen.com/books/images_new/9343.jpg",editors:[{id:"255959",title:"Dr.",name:"Mario Alfonso",middleName:null,surname:"Murillo-Tovar",slug:"mario-alfonso-murillo-tovar",fullName:"Mario Alfonso Murillo-Tovar"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"8468",title:"Sheep Farming",subtitle:"An Approach to Feed, Growth and Sanity",isOpenForSubmission:!1,hash:"838f08594850bc04aa14ec873ed1b96f",slug:"sheep-farming-an-approach-to-feed-growth-and-sanity",bookSignature:"António Monteiro",coverURL:"https://cdn.intechopen.com/books/images_new/8468.jpg",editors:[{id:"190314",title:"Prof.",name:"António",middleName:"Cardoso",surname:"Monteiro",slug:"antonio-monteiro",fullName:"António Monteiro"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"8816",title:"Financial Crises",subtitle:"A Selection of Readings",isOpenForSubmission:!1,hash:"6f2f49fb903656e4e54280c79fabd10c",slug:"financial-crises-a-selection-of-readings",bookSignature:"Stelios Markoulis",coverURL:"https://cdn.intechopen.com/books/images_new/8816.jpg",editors:[{id:"237863",title:"Dr.",name:"Stelios",middleName:null,surname:"Markoulis",slug:"stelios-markoulis",fullName:"Stelios Markoulis"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"7831",title:"Sustainability in Urban Planning and Design",subtitle:null,isOpenForSubmission:!1,hash:"c924420492c8c2c9751e178d025f4066",slug:"sustainability-in-urban-planning-and-design",bookSignature:"Amjad Almusaed, Asaad Almssad and Linh Truong - Hong",coverURL:"https://cdn.intechopen.com/books/images_new/7831.jpg",editors:[{id:"110471",title:"Dr.",name:"Amjad",middleName:"Zaki",surname:"Almusaed",slug:"amjad-almusaed",fullName:"Amjad Almusaed"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"9376",title:"Contemporary Developments and Perspectives in International Health Security",subtitle:"Volume 1",isOpenForSubmission:!1,hash:"b9a00b84cd04aae458fb1d6c65795601",slug:"contemporary-developments-and-perspectives-in-international-health-security-volume-1",bookSignature:"Stanislaw P. Stawicki, Michael S. Firstenberg, Sagar C. Galwankar, Ricardo Izurieta and Thomas Papadimos",coverURL:"https://cdn.intechopen.com/books/images_new/9376.jpg",editors:[{id:"181694",title:"Dr.",name:"Stanislaw P.",middleName:null,surname:"Stawicki",slug:"stanislaw-p.-stawicki",fullName:"Stanislaw P. Stawicki"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}},{type:"book",id:"7769",title:"Medical Isotopes",subtitle:null,isOpenForSubmission:!1,hash:"f8d3c5a6c9a42398e56b4e82264753f7",slug:"medical-isotopes",bookSignature:"Syed Ali Raza Naqvi and Muhammad Babar Imrani",coverURL:"https://cdn.intechopen.com/books/images_new/7769.jpg",editors:[{id:"259190",title:"Dr.",name:"Syed Ali Raza",middleName:null,surname:"Naqvi",slug:"syed-ali-raza-naqvi",fullName:"Syed Ali Raza Naqvi"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],latestBooks:[{type:"book",id:"8468",title:"Sheep Farming",subtitle:"An Approach to Feed, Growth and Sanity",isOpenForSubmission:!1,hash:"838f08594850bc04aa14ec873ed1b96f",slug:"sheep-farming-an-approach-to-feed-growth-and-sanity",bookSignature:"António Monteiro",coverURL:"https://cdn.intechopen.com/books/images_new/8468.jpg",editedByType:"Edited by",editors:[{id:"190314",title:"Prof.",name:"António",middleName:"Cardoso",surname:"Monteiro",slug:"antonio-monteiro",fullName:"António Monteiro"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9523",title:"Oral and Maxillofacial Surgery",subtitle:null,isOpenForSubmission:!1,hash:"5eb6ec2db961a6c8965d11180a58d5c1",slug:"oral-and-maxillofacial-surgery",bookSignature:"Gokul Sridharan",coverURL:"https://cdn.intechopen.com/books/images_new/9523.jpg",editedByType:"Edited by",editors:[{id:"82453",title:"Dr.",name:"Gokul",middleName:null,surname:"Sridharan",slug:"gokul-sridharan",fullName:"Gokul Sridharan"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9785",title:"Endometriosis",subtitle:null,isOpenForSubmission:!1,hash:"f457ca61f29cf7e8bc191732c50bb0ce",slug:"endometriosis",bookSignature:"Courtney Marsh",coverURL:"https://cdn.intechopen.com/books/images_new/9785.jpg",editedByType:"Edited by",editors:[{id:"255491",title:"Dr.",name:"Courtney",middleName:null,surname:"Marsh",slug:"courtney-marsh",fullName:"Courtney Marsh"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9018",title:"Some RNA Viruses",subtitle:null,isOpenForSubmission:!1,hash:"a5cae846dbe3692495fc4add2f60fd84",slug:"some-rna-viruses",bookSignature:"Yogendra Shah and Eltayb Abuelzein",coverURL:"https://cdn.intechopen.com/books/images_new/9018.jpg",editedByType:"Edited by",editors:[{id:"278914",title:"Ph.D.",name:"Yogendra",middleName:null,surname:"Shah",slug:"yogendra-shah",fullName:"Yogendra Shah"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"8816",title:"Financial Crises",subtitle:"A Selection of Readings",isOpenForSubmission:!1,hash:"6f2f49fb903656e4e54280c79fabd10c",slug:"financial-crises-a-selection-of-readings",bookSignature:"Stelios Markoulis",coverURL:"https://cdn.intechopen.com/books/images_new/8816.jpg",editedByType:"Edited by",editors:[{id:"237863",title:"Dr.",name:"Stelios",middleName:null,surname:"Markoulis",slug:"stelios-markoulis",fullName:"Stelios Markoulis"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9585",title:"Advances in Complex Valvular Disease",subtitle:null,isOpenForSubmission:!1,hash:"ef64f11e211621ecfe69c46e60e7ca3d",slug:"advances-in-complex-valvular-disease",bookSignature:"Michael S. Firstenberg and Imran Khan",coverURL:"https://cdn.intechopen.com/books/images_new/9585.jpg",editedByType:"Edited by",editors:[{id:"64343",title:null,name:"Michael S.",middleName:"S",surname:"Firstenberg",slug:"michael-s.-firstenberg",fullName:"Michael S. Firstenberg"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"10150",title:"Smart Manufacturing",subtitle:"When Artificial Intelligence Meets the Internet of Things",isOpenForSubmission:!1,hash:"87004a19de13702d042f8ff96d454698",slug:"smart-manufacturing-when-artificial-intelligence-meets-the-internet-of-things",bookSignature:"Tan Yen Kheng",coverURL:"https://cdn.intechopen.com/books/images_new/10150.jpg",editedByType:"Edited by",editors:[{id:"78857",title:"Dr.",name:"Tan Yen",middleName:null,surname:"Kheng",slug:"tan-yen-kheng",fullName:"Tan Yen Kheng"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9386",title:"Direct Numerical Simulations",subtitle:"An Introduction and Applications",isOpenForSubmission:!1,hash:"158a3a0fdba295d21ff23326f5a072d5",slug:"direct-numerical-simulations-an-introduction-and-applications",bookSignature:"Srinivasa Rao",coverURL:"https://cdn.intechopen.com/books/images_new/9386.jpg",editedByType:"Edited by",editors:[{id:"6897",title:"Dr.",name:"Srinivasa",middleName:"P",surname:"Rao",slug:"srinivasa-rao",fullName:"Srinivasa Rao"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9139",title:"Topics in Primary Care Medicine",subtitle:null,isOpenForSubmission:!1,hash:"ea774a4d4c1179da92a782e0ae9cde92",slug:"topics-in-primary-care-medicine",bookSignature:"Thomas F. Heston",coverURL:"https://cdn.intechopen.com/books/images_new/9139.jpg",editedByType:"Edited by",editors:[{id:"217926",title:"Dr.",name:"Thomas F.",middleName:null,surname:"Heston",slug:"thomas-f.-heston",fullName:"Thomas F. Heston"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"9208",title:"Welding",subtitle:"Modern Topics",isOpenForSubmission:!1,hash:"7d6be076ccf3a3f8bd2ca52d86d4506b",slug:"welding-modern-topics",bookSignature:"Sadek Crisóstomo Absi Alfaro, Wojciech Borek and Błażej Tomiczek",coverURL:"https://cdn.intechopen.com/books/images_new/9208.jpg",editedByType:"Edited by",editors:[{id:"65292",title:"Prof.",name:"Sadek Crisostomo Absi",middleName:"C. Absi",surname:"Alfaro",slug:"sadek-crisostomo-absi-alfaro",fullName:"Sadek Crisostomo Absi Alfaro"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}]},subject:{topic:{id:"506",title:"Environmental Chemistry",slug:"chemistry-physical-chemistry-environmental-chemistry",parent:{title:"Physical Chemistry",slug:"chemistry-physical-chemistry"},numberOfBooks:2,numberOfAuthorsAndEditors:42,numberOfWosCitations:124,numberOfCrossrefCitations:49,numberOfDimensionsCitations:155,videoUrl:null,fallbackUrl:null,description:null},booksByTopicFilter:{topicSlug:"chemistry-physical-chemistry-environmental-chemistry",sort:"-publishedDate",limit:12,offset:0},booksByTopicCollection:[{type:"book",id:"2351",title:"Hydrocarbon",subtitle:null,isOpenForSubmission:!1,hash:"3c36253544ea6a0c636f352cd71eb746",slug:"hydrocarbon",bookSignature:"Vladimir Kutcherov and Anton Kolesnikov",coverURL:"https://cdn.intechopen.com/books/images_new/2351.jpg",editedByType:"Edited by",editors:[{id:"134096",title:"Prof.",name:"Vladimir",middleName:null,surname:"Kutcherov",slug:"vladimir-kutcherov",fullName:"Vladimir Kutcherov"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}},{type:"book",id:"1529",title:"Green Chemistry",subtitle:"Environmentally Benign Approaches",isOpenForSubmission:!1,hash:"399f5102c2934a2ea8484fe4fd6313dc",slug:"green-chemistry-environmentally-benign-approaches",bookSignature:"Mazaahir Kidwai and Neeraj Kumar Mishra",coverURL:"https://cdn.intechopen.com/books/images_new/1529.jpg",editedByType:"Edited by",editors:[{id:"105309",title:"Dr.",name:"Neeraj Kumar",middleName:null,surname:"Mishra",slug:"neeraj-kumar-mishra",fullName:"Neeraj Kumar Mishra"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter",authoredCaption:"Edited by"}}],booksByTopicTotal:2,mostCitedChapters:[{id:"41885",doi:"10.5772/48176",title:"Polycyclic Aromatic Hydrocarbons a Constituent of Petroleum: Presence and Influence in the Aquatic Environment",slug:"polycyclic-aromatic-hydrocarbons-a-constituent-of-petroleum-presence-and-influence-in-the-aquatic-en",totalDownloads:8950,totalCrossrefCites:20,totalDimensionsCites:82,book:{slug:"hydrocarbon",title:"Hydrocarbon",fullTitle:"Hydrocarbon"},signatures:"Daniela M. Pampanin and Magne O. Sydnes",authors:[{id:"139987",title:"Dr",name:null,middleName:null,surname:"Sydnes",slug:"sydnes",fullName:"Sydnes"},{id:"143899",title:"Dr.",name:"Daniela",middleName:null,surname:"Pampanin",slug:"daniela-pampanin",fullName:"Daniela Pampanin"}]},{id:"41886",doi:"10.5772/50108",title:"Petroleum Hydrocarbon Biodegradability in Soil – Implications for Bioremediation",slug:"petroleum-hydrocarbon-biodegradability-in-soil-implications-for-bioremediation",totalDownloads:9850,totalCrossrefCites:4,totalDimensionsCites:15,book:{slug:"hydrocarbon",title:"Hydrocarbon",fullTitle:"Hydrocarbon"},signatures:"Snežana Maletić, Božo Dalmacija and Srđan Rončevic",authors:[{id:"139471",title:"Dr.",name:"Snežana",middleName:null,surname:"Maletić",slug:"snezana-maletic",fullName:"Snežana Maletić"},{id:"143525",title:"Prof.",name:"Božo",middleName:null,surname:"Dalmacija",slug:"bozo-dalmacija",fullName:"Božo Dalmacija"},{id:"143527",title:"Dr.",name:"Srđan",middleName:null,surname:"Rončević",slug:"srdjan-roncevic",fullName:"Srđan Rončević"}]},{id:"41890",doi:"10.5772/51591",title:"Remediation of Contaminated Sites",slug:"remediation-of-contaminated-sites",totalDownloads:6688,totalCrossrefCites:4,totalDimensionsCites:14,book:{slug:"hydrocarbon",title:"Hydrocarbon",fullTitle:"Hydrocarbon"},signatures:"Arezoo Dadrasnia, N. Shahsavari and C. U. Emenike",authors:[{id:"139848",title:"Dr.",name:"Arezoo",middleName:null,surname:"Dadrasnia",slug:"arezoo-dadrasnia",fullName:"Arezoo Dadrasnia"}]}],mostDownloadedChaptersLast30Days:[{id:"41886",title:"Petroleum Hydrocarbon Biodegradability in Soil – Implications for Bioremediation",slug:"petroleum-hydrocarbon-biodegradability-in-soil-implications-for-bioremediation",totalDownloads:9850,totalCrossrefCites:4,totalDimensionsCites:15,book:{slug:"hydrocarbon",title:"Hydrocarbon",fullTitle:"Hydrocarbon"},signatures:"Snežana Maletić, Božo Dalmacija and Srđan Rončevic",authors:[{id:"139471",title:"Dr.",name:"Snežana",middleName:null,surname:"Maletić",slug:"snezana-maletic",fullName:"Snežana Maletić"},{id:"143525",title:"Prof.",name:"Božo",middleName:null,surname:"Dalmacija",slug:"bozo-dalmacija",fullName:"Božo Dalmacija"},{id:"143527",title:"Dr.",name:"Srđan",middleName:null,surname:"Rončević",slug:"srdjan-roncevic",fullName:"Srđan Rončević"}]},{id:"41885",title:"Polycyclic Aromatic Hydrocarbons a Constituent of Petroleum: Presence and Influence in the Aquatic Environment",slug:"polycyclic-aromatic-hydrocarbons-a-constituent-of-petroleum-presence-and-influence-in-the-aquatic-en",totalDownloads:8950,totalCrossrefCites:20,totalDimensionsCites:82,book:{slug:"hydrocarbon",title:"Hydrocarbon",fullTitle:"Hydrocarbon"},signatures:"Daniela M. Pampanin and Magne O. Sydnes",authors:[{id:"139987",title:"Dr",name:null,middleName:null,surname:"Sydnes",slug:"sydnes",fullName:"Sydnes"},{id:"143899",title:"Dr.",name:"Daniela",middleName:null,surname:"Pampanin",slug:"daniela-pampanin",fullName:"Daniela Pampanin"}]},{id:"41888",title:"Characterizing Microbial Activity and Diversity of Hydrocarbon-Contaminated Sites",slug:"characterizing-microbial-activity-and-diversity-of-hydrocarbon-contaminated-sites",totalDownloads:2695,totalCrossrefCites:5,totalDimensionsCites:6,book:{slug:"hydrocarbon",title:"Hydrocarbon",fullTitle:"Hydrocarbon"},signatures:"Aizhong Ding, Yujiao Sun, Junfeng Dou, Lirong Cheng, Lin Jiang, Dan Zhang and Xiaohui Zhao",authors:[{id:"141653",title:"Prof.",name:"Aizhong",middleName:null,surname:"Ding",slug:"aizhong-ding",fullName:"Aizhong Ding"}]},{id:"41890",title:"Remediation of Contaminated Sites",slug:"remediation-of-contaminated-sites",totalDownloads:6688,totalCrossrefCites:4,totalDimensionsCites:14,book:{slug:"hydrocarbon",title:"Hydrocarbon",fullTitle:"Hydrocarbon"},signatures:"Arezoo Dadrasnia, N. Shahsavari and C. U. Emenike",authors:[{id:"139848",title:"Dr.",name:"Arezoo",middleName:null,surname:"Dadrasnia",slug:"arezoo-dadrasnia",fullName:"Arezoo Dadrasnia"}]},{id:"33320",title:"Green Chemistry – Aspects for the Knoevenagel Reaction",slug:"green-chemistry-aspects-for-knoevenagel-reaction-",totalDownloads:20524,totalCrossrefCites:2,totalDimensionsCites:5,book:{slug:"green-chemistry-environmentally-benign-approaches",title:"Green Chemistry",fullTitle:"Green Chemistry - Environmentally Benign Approaches"},signatures:"Ricardo Menegatti",authors:[{id:"108535",title:"Dr.",name:"Ricardo",middleName:null,surname:"Menegatti",slug:"ricardo-menegatti",fullName:"Ricardo Menegatti"}]},{id:"41889",title:"Abiogenic Deep Origin of Hydrocarbons and Oil and Gas Deposits Formation",slug:"abiogenic-deep-origin-of-hydrocarbons-and-oil-and-gas-deposits-formation",totalDownloads:6891,totalCrossrefCites:2,totalDimensionsCites:5,book:{slug:"hydrocarbon",title:"Hydrocarbon",fullTitle:"Hydrocarbon"},signatures:"Vladimir G. Kutcherov",authors:[{id:"134096",title:"Prof.",name:"Vladimir",middleName:null,surname:"Kutcherov",slug:"vladimir-kutcherov",fullName:"Vladimir Kutcherov"}]},{id:"33319",title:"Greenwashing and Cleaning",slug:"greenwashing-and-cleaning",totalDownloads:1897,totalCrossrefCites:0,totalDimensionsCites:0,book:{slug:"green-chemistry-environmentally-benign-approaches",title:"Green Chemistry",fullTitle:"Green Chemistry - Environmentally Benign Approaches"},signatures:"Develter Dirk and Malaise Peter",authors:[{id:"115269",title:"Mr.",name:"Dirk",middleName:null,surname:"Develter",slug:"dirk-develter",fullName:"Dirk Develter"},{id:"115270",title:"Mr.",name:"Peter",middleName:null,surname:"Malaise",slug:"peter-malaise",fullName:"Peter Malaise"}]},{id:"41882",title:"Thermogenic Methane with Secondary Alteration in Gases Released from Terrestrial Mud Volcanoes",slug:"thermogenic-methane-with-secondary-alteration-in-gases-released-from-terrestrial-mud-volcanoes",totalDownloads:2540,totalCrossrefCites:0,totalDimensionsCites:0,book:{slug:"hydrocarbon",title:"Hydrocarbon",fullTitle:"Hydrocarbon"},signatures:"Ryoichi Nakada and Yoshio Takahashi",authors:[{id:"140819",title:"Dr.",name:"Ryoichi",middleName:null,surname:"Nakada",slug:"ryoichi-nakada",fullName:"Ryoichi Nakada"},{id:"154768",title:"Prof.",name:"Yoshio",middleName:null,surname:"Takahashi",slug:"yoshio-takahashi",fullName:"Yoshio Takahashi"}]},{id:"41891",title:"Phenanthrene Removal from Soil by a Strain of Aspergillus niger Producing Manganese Peroxidase of Phanerochaete chrysosporium",slug:"phenanthrene-removal-from-soil-by-a-strain-of-aspergillus-niger-producing-manganese-peroxidase-of-ph",totalDownloads:3326,totalCrossrefCites:0,totalDimensionsCites:5,book:{slug:"hydrocarbon",title:"Hydrocarbon",fullTitle:"Hydrocarbon"},signatures:"Diana V. Cortés-Espinosa and Ángel E. Absalón",authors:[{id:"141081",title:"Prof.",name:"Diana",middleName:"V.",surname:"Cortés-Espinosa",slug:"diana-cortes-espinosa",fullName:"Diana Cortés-Espinosa"},{id:"144099",title:"Dr.",name:"Angel E.",middleName:null,surname:"Absalón",slug:"angel-e.-absalon",fullName:"Angel E. Absalón"}]},{id:"33324",title:"Greener Solvent-Free Reactions on ZnO",slug:"greener-solvent-free-reactions-on-zno-",totalDownloads:6607,totalCrossrefCites:0,totalDimensionsCites:0,book:{slug:"green-chemistry-environmentally-benign-approaches",title:"Green Chemistry",fullTitle:"Green Chemistry - Environmentally Benign Approaches"},signatures:"Mona Hosseini-Sarvari",authors:[{id:"98172",title:"Dr.",name:"Mona",middleName:null,surname:"Hosseini-Sarvari",slug:"mona-hosseini-sarvari",fullName:"Mona Hosseini-Sarvari"}]}],onlineFirstChaptersFilter:{topicSlug:"chemistry-physical-chemistry-environmental-chemistry",limit:3,offset:0},onlineFirstChaptersCollection:[],onlineFirstChaptersTotal:0},preDownload:{success:null,errors:{}},aboutIntechopen:{},privacyPolicy:{},peerReviewing:{},howOpenAccessPublishingWithIntechopenWorks:{},sponsorshipBooks:{sponsorshipBooks:[{type:"book",id:"10176",title:"Microgrids and Local Energy Systems",subtitle:null,isOpenForSubmission:!0,hash:"c32b4a5351a88f263074b0d0ca813a9c",slug:null,bookSignature:"Prof. Nick Jenkins",coverURL:"https://cdn.intechopen.com/books/images_new/10176.jpg",editedByType:null,editors:[{id:"55219",title:"Prof.",name:"Nick",middleName:null,surname:"Jenkins",slug:"nick-jenkins",fullName:"Nick Jenkins"}],equalEditorOne:null,equalEditorTwo:null,equalEditorThree:null,productType:{id:"1",chapterContentType:"chapter"}}],offset:8,limit:8,total:1},route:{name:"profile.detail",path:"/profiles/306841/francisco-perez-martinez",hash:"",query:{},params:{id:"306841",slug:"francisco-perez-martinez"},fullPath:"/profiles/306841/francisco-perez-martinez",meta:{},from:{name:null,path:"/",hash:"",query:{},params:{},fullPath:"/",meta:{}}}},function(){var e;(e=document.currentScript||document.scripts[document.scripts.length-1]).parentNode.removeChild(e)}()