This chapter presents the volume fraction distribution of kerosene-water two-phase flow in vertical and inclined pipes. The study of liquid-liquid two-phase flow is very significant to oil industry and many other processes in industry where two liquids are mixed and flow together. Pitot tube and optical probes are used for the measurement of velocity of water and volume fraction. The experimental measurements of the local parameters demonstrate that the single-phase and two-phase flows reached the fully developed axisymmetric conditions at L/D ≥ 48 (L, pipe length; D, pipe diameter). The results also showed the severe asymmetry distributions of the volume fraction at the entrance region (L/D = 1) downstream the bend and in the inclined pipe. The comparison of volume fraction profiles with void fraction profiles indicated a significant difference in their shapes. The results also showed that the kerosene accumulated at the upper wall of the inclined pipe and the distribution improved by increasing the volumetric quality.