Aflatoxin B1 (AFB1) is harmful to human health, mainly resulting from its toxic effects on the liver. AFB1 can lead to liver cell necrosis, hemorrhage, fibrosis, cirrhosis, etc. Acute AFB1 exposure at high levels can lead to hepatitis, whereas chronic exposure can result in liver cancer. In the past decades, a series of methods and techniques for detecting AFB1, including enzyme-linked immunosorbent assay (ELISA), high-performance liquid chromatography (HPLC), and thin-layer chromatography (TLC), have been developed. This study reviewed the detection methods of AFB1 and the corresponding utilization and summarizes all methods for evaluating the toxification of AFB1.
Part of the book: Aflatoxin B1 Occurrence, Detection and Toxicological Effects