Brucellosis, a prevalent zoonosis disease in different countries, can involve the kidney during infection and also present in the complicated form in hemodialysis (HD), peritoneal dialysis (PD), and kidney transplant (Tx) patient. In spite of few reports of kidney involvements in the literature, this infection can imitate a wide range of glomerular disease from minimal change, membranous glomeropathy, focal and diffuse proliferative glomerular disease to rapidly progressive glomerulonephritis. Cryoglobulinemia, thrombotic microangiopathy, and ANCA-associated glomerular disease are vasculitis form of the disease. Tubulointerstitial involvement, electrolyte disorder, renal abscess, and pyelonephritis can present the same as other Gram-negative infections. Moreover, peritonitis in PD patient, spondyloarthropathy in HD, and severe infection in kidney Tx patients have been reported. Infection recurrence and infection from kidney donors are another dilemma in renal recipients. Brucellosis as a multifaced disease can mimic a wide range of presentations in nephrology. Clinicians should keep in mind the diverse pictures of the disease, especially when they practice in the endemic area.
Part of the book: New Insight into Brucella Infection and Foodborne Diseases