Osteosarcoma accounts for 3% of all malignant tumors, 35–50% of all malignant bone tumors in pediatric patients. The chapter contains statistical data describing the incidence of the child population of osteosarcomas, classification of osteosarcomas, staging principles, a description of the main localizations, as well as a detailed description of the existing treatment protocols for children with osteosarcomas, including personalized therapy. The literature data are described in detail—the results of treatment of children with osteosarcoma with various courses of chemotherapy, as well as new approaches in treatment, including personalized therapy. But the results of treatment of children with primary metastatic osteosarcoma, relapse, and refractory course of the disease remain unsatisfactory.
Part of the book: Osteosarcoma