Chapters authored
Risk-Benefit Events Associated with the Use of Aspirin for Primary Prevention of Cardiovascular Disorders
Aspirin had been introduced as a nonsteroidal anti-inflammatory molecule. As further research on aspirin started, other therapeutic effects have been revealed. Now, this molecule has become the polychrest in medical science. Aspirin has served as a drug of choice for the primary prevention of cardiovascular disease (CVD) for the last few decades. However, recent trials have raised questions on the use of aspirin for CVD prevention due to some life-threatening adverse drug events. In spite of that, outcomes of trials will surely assist to frame a guideline for anoxic administration regimen of aspirin in order to prevent CVD.
Part of the book: Drug Repurposing
Revisiting the Medicinal Value of Terpenes and Terpenoids
Nowadays, plant-based chemicals have drawn the attention of pharmacy researchers due to their potent biological activity against various ailments. In this series, terpenes and terpenoids are gaining popularity among drug researchers gradually. Terpenes are naturally occurring large and varied class of hydrocarbons substances produced by a wide variety of plants including fruits, vegetables, flowers and some animals. Their concentration is generally high in plants. A broad range of the biological properties of terpenoids includes cancer chemo-preventive effects, antimicrobial, antifungal, antiviral, anti-hyperglycemic, anti-inflammatory, anti-parasitic activities and memory enhancers. Terpenoids are usually cyclic unsaturated hydrocarbons, with the altered number of oxygen moieties in the constituent groups attached to the basic isoprene skeleton. Terpenoids are a group of substances that occur in nearly every natural food. Terpenoids display a wide range of biological activities against cancer, malaria, inflammation, tuberculosis and a variety of infectious diseases including viral as well as bacterial. In this chapter, we have emphasized the proven and expected medicinal value of both terpenes and terpenoids.
Part of the book: Revisiting Plant Biostimulants