Melatonin (MLT) was isolated as a hormone by Lerner in 1958, and since then, intense studies have been under way with respect to its action and possibilities of application in various fields of medicine. Despite the existence of multiple antiepileptic medications and progress that has taken place in neurosurgical treatment of epilepsy, drug-resistant epilepsy continues to be a phenomenon that occurs in 30–35% children treated for epileptic seizures. Reports presented in the study have shown that children with epilepsy suffer from sleep disorders. Sleep deprivation may cause seizures, and on the other hand, an increased frequency of seizures may lead to sleep disturbances.
Part of the book: Melatonin