Inga Zerr

Augusta UniversityUnited States of America

Inga Zerr is Professor at the Department of Neurology and Chair of the Clinical Dementia Center at the University Medical School, Göttingen. She received her habilitation (venia legendi for neurology) in 2001 for her work on cerebrospinal fluid in human prion diseases. With over 180 publications, Inga Zerr\'s current research interests include clinicopathological characterisation of molecular disease subtypes in neurodegenerative dementia (such as prion diseases, Alzheimer’s disease) and the understanding of the molecular basis which leads to the phenotypic diversity in these pathological conditions.

2books edited

2chapters authored

Latest work with IntechOpen by Inga Zerr

There is a wide scope of clinical phenomenology in Alzheimers disease, regarding the age of onset, presenting features, rate of progression and appearance of other clinical manifestation. Although clinical appearance and neuropathological hallmarks have been defining AD since its first description, major factors which trigger pathology are still unknown. The role of comorbidity is discussed controversially. Important environmental risk factors in AD development are continuous stress, low education and cardiovascular risk factors such as alcohol intake, smoking, hypertension. The role of lipids and cholesterol has been recognized, but the relevant pathogenetic steps are still to be identified. There is an urgent need to understand molecular disease pathogenesis in order to develop early therapeutic targets for the disease.

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