Renos Savva

Birkbeck, University of London

Renos Savva is a Senior Lecturer at Birkbeck, University of London. His research interests are in the interactions of viruses with their cellular host environments, particularly those of viral proteins with nucleic acids, and with host-encoded proteins. Dr. Savva’s research concerns the nature of viral survival mechanisms, such as viral replicative switches, evasion of host restriction factors, and the adaptation and sequence plasticity of virus-encoded proteins. Dr. Savva’s published research includes insights from the structural biology of phage-encoded inhibitors of the ubiquitous family-1 uracil-DNA glycosylase, Ung. His research also extends to questions of protein sequence plasticity, which crosses over into synthetic biology collaborations: On the one hand, how adaptable are essential phage proteins, and on the other, how interchangeable are structural components of phage from closely related genomic families.